Applications of protein ubiquitylation and deubiquitylation in drug discovery.
Chen Y, Xue H, Jin J.
J Biol Chem · research support, non-u.s. gov't; review-article; review; journal article · DOI 10.1016/j.jbc.2024.107264 PUBLIKATIONSREGISTRET
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Nat Chem Biol · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1038/s41589-023-01409-zMolecular Glues: Capable Protein-Binding Small Molecules That Can Change Protein-Protein Interactions and Interactomes for the Potential Treatment of Human Cancer and Neurodegenerative Diseases.
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Nat Rev Cancer · research support, non-u.s. gov't; research-article; review; journal article; research support, n.i.h., extramural · DOI 10.1038/s41568-021-00365-xRational discovery of molecular glue degraders via scalable chemical profiling.
Mayor-Ruiz C, Bauer S, Brand M, Kozicka Z, Siklos M, Imrichova H, Kaltheuner IH, Hahn E, Seiler K, Koren A, Petzold G, Fellner M, Bock C, Müller AC, Zuber J, Geyer M, Thomä NH, Kubicek S, Winter GE.
Nat Chem Biol · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/s41589-020-0594-x