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Publikationer i urvalet

23 träffar

Bibliografisk träff 2024-08-29

Ferulic acid suppresses the inflammation and apoptosis in Kawasaki disease through activating the AMPK/mTOR/NF-κB pathway.

Wu H, Wang Y, Tan P, Ran Y, Guan Y, Qian S, Feng X, Jiang Y, Peng Y, Sheng K, Xi H, Ji W, Guo X.

Front Pharmacol · research-article; journal article · DOI 10.3389/fphar.2024.1420602

Bibliografisk träff 2024-07-31

Senolytics and Senomorphics Targeting p38MAPK/NF-κB Pathway Protect Endothelial Cells from Oxidative Stress-Mediated Premature Senescence.

Ya J, Bayraktutan U.

Cells · research-article; journal article · DOI 10.3390/cells13151292

Bibliografisk träff 2024-01-01

Fatty acid binding protein 4 (FABP4) induces chondrocyte degeneration via activation of the NF-κb signaling pathway.

Zhang C, Lin Y, Li H, Hu H, Chen Y, Huang Y, Huang Z, Fang X, Zhang W, Lin Y.

FASEB J · research support, non-u.s. gov't; journal article · DOI 10.1096/fj.202301882r

Bibliografisk träff 2023-05-15

A quinazoline derivative suppresses B cell hyper-activation and ameliorates the severity of systemic lupus erythematosus in mice.

Zhang G, Yang F, Li J, Chen S, Kong Y, Mo C, Leng X, Liu Y, Xu Y, Wang Y.

Front Pharmacol · research-article; journal article · DOI 10.3389/fphar.2023.1159075

Bibliografisk träff 2023-04-25

Chemical Genetics Screen of EVP4593 Sensitivity in Budding Yeast Identifies Effects on Mitochondrial Structure and Function.

Hiestand L, Shen S, Sloan W, Nasiri H, Lashley D, Kerscher O.

MicroPubl Biol · brief-report; journal article · DOI 10.17912/micropub.biology.000806

Bibliografisk träff 2023-04-22

Synergistic Effect of QNZ, an Inhibitor of NF-κB Signaling, and Bone Morphogenetic Protein 2 on Osteogenic Differentiation in Mesenchymal Stem Cells through Fibroblast-Induced Yes-Associated Protein Activation.

Huang F, Wang H, Zhang Y, Wei G, Xie Y, Wu G.

Int J Mol Sci · research-article; journal article · DOI 10.3390/ijms24097707

Bibliografisk träff 2023-02-16

QNZ exposure induces development toxicity and mechanisms of hatching inhibition in large-scale loach (Paramisgurnus dabryanus) embryos.

Xia X, Ma X, Liang N, Duan X, Wang S, Guo W, Chang Z.

Ecotoxicol Environ Saf · journal article · DOI 10.1016/j.ecoenv.2023.114663

Bibliografisk träff 2022-12-15

Drug Repurposing Using Gene Co-Expression and Module Preservation Analysis in Acute Respiratory Distress Syndrome (ARDS), Systemic Inflammatory Response Syndrome (SIRS), Sepsis, and COVID-19.

Mailem RC, Tayo LL.

Biology (Basel) · research-article; journal article · DOI 10.3390/biology11121827

Bibliografisk träff 2022-12-11

The Mystery of EVP4593: Perspectives of the Quinazoline-Derived Compound in the Treatment of Huntington's Disease and Other Human Pathologies.

Grekhnev DA, Kruchinina AA, Vigont VA, Kaznacheyeva EV.

Int J Mol Sci · review-article; review; journal article · DOI 10.3390/ijms232415724

Bibliografisk träff 2022-11-09

NDUFS3 knockout cancer cells and molecular docking reveal specificity and mode of action of anti-cancer respiratory complex I inhibitors.

Kurelac I, Cavina B, Sollazzo M, Miglietta S, Fornasa A, De Luise M, Iorio M, Lama E, Traversa D, Nasiri HR, Ghelli A, Musiani F, Porcelli AM, Iommarini L, Gasparre G.

Open Biol · research support, non-u.s. gov't; research-article; journal article · DOI 10.1098/rsob.220198

Bibliografisk träff 2022-07-01

[Effect of the NF-κB/iNOS Signaling Pathway on Spiral Ganglion in Mouse Model of Sensorineural Hearing Loss].

Chen K, Zhao R, Zhou L, Long LL, Tang YD.

Sichuan Da Xue Xue Bao Yi Xue Ban · research-article; journal article · DOI 10.12182/20220760206

Bibliografisk träff 2021-10-18

New targets of morphine postconditioning protection of the myocardium in ischemia/reperfusion injury: Involvement of HSP90/Akt and C5a/NF-κB.

Tu RH, Wang DX, Zhong GQ, Meng JJ, Wen H, Jie-Feng, Bi Q, He Y.

Open Med (Wars) · research-article; journal article · DOI 10.1515/med-2021-0340

Bibliografisk träff 2021-09-24

QNZ alleviated hepatocellular carcinoma by targeting inflammatory pathways in a rat model.

Al-Gayyar MMH, Alattar A, Alshaman R, Hamdan AM.

Cytokine · journal article · DOI 10.1016/j.cyto.2021.155710

Bibliografisk träff 2020-05-01

NF-κB inhibitor QNZ protects human chondrocyte degeneration by promoting glucose uptake through Glut4 activation.

Zhu SB, Xu YQ, Gao H, Deng Y.

Eur Rev Med Pharmacol Sci · journal article · DOI 10.26355/eurrev_202005_21150

Bibliografisk träff 2019-05-02

Antagonist of neuronal store-operated calcium entry exerts beneficial effects in neurons expressing PSEN1ΔE9 mutant linked to familial Alzheimer disease.

Chernyuk D, Zernov N, Kabirova M, Bezprozvanny I, Popugaeva E.

Neuroscience · research support, non-u.s. gov't; journal article · DOI 10.1016/j.neuroscience.2019.04.043

Bibliografisk träff 2019-01-30

High-Throughput Screening Identified Compounds Sensitizing Tumor Cells to Glucose Starvation in Culture and VEGF Inhibitors In Vivo.

Marciano R, Prasad M, Ievy T, Tzadok S, Leprivier G, Elkabets M, Rotblat B.

Cancers (Basel) · research-article; journal article · DOI 10.3390/cancers11020156

Bibliografisk träff 2018-12-07

Screening of a drug repurposing library with a nematode motility assay identifies promising anthelmintic hits against Cooperia oncophora and other ruminant parasites.

Liu M, Landuyt B, Klaassen H, Geldhof P, Luyten W.

Vet Parasitol · journal article · DOI 10.1016/j.vetpar.2018.11.014

Bibliografisk träff 2018-09-01

Fluoxetine Inhibits DNA Repair and NF-ĸB-modulated Metastatic Potential in Non-small Cell Lung Cancer.

Wu JY, Lin SS, Hsu FT, Chung JG.

Anticancer Res · journal article · DOI 10.21873/anticanres.12843

Bibliografisk träff 2017-05-09

Regorafenib diminishes the expression and secretion of angiogenesis and metastasis associated proteins and inhibits cell invasion via NF-κB inactivation in SK-Hep1 cells.

Liu YC, Wu RH, Wang WS.

Oncol Lett · research-article; journal article · DOI 10.3892/ol.2017.6142

Bibliografisk träff 2017-03-14

A novel quinazoline-based analog induces G2/M cell cycle arrest and apoptosis in human A549 lung cancer cells via a ROS-dependent mechanism.

Shi H, Li Y, Ren X, Zhang Y, Yang Z, Qi C.

Biochem Biophys Res Commun · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bbrc.2017.03.034

Bibliografisk träff 2017-02-20

Identification of 4-<i>N</i>-[2-(4-phenoxyphenyl)ethyl]quinazoline-4,6-diamine as a novel, highly potent and specific inhibitor of mitochondrial complex I.

Krishnathas R, Bonke E, Dröse S, Zickermann V, Nasiri HR.

Medchemcomm · research-article; journal article · DOI 10.1039/c6md00655h

Bibliografisk träff 2016-12-20

Regorafenib induces extrinsic and intrinsic apoptosis through inhibition of ERK/NF-κB activation in hepatocellular carcinoma cells.

Tsai JJ, Pan PJ, Hsu FT.

Oncol Rep · journal article · DOI 10.3892/or.2016.5328

Bibliografisk träff 2011-06-01

Neuronal store-operated calcium entry pathway as a novel therapeutic target for Huntington's disease treatment.

Wu J, Shih HP, Vigont V, Hrdlicka L, Diggins L, Singh C, Mahoney M, Chesworth R, Shapiro G, Zimina O, Chen X, Wu Q, Glushankova L, Ahlijanian M, Koenig G, Mozhayeva GN, Kaznacheyeva E, Bezprozvanny I.

Chem Biol · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.chembiol.2011.04.012