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Publikationer i urvalet

10 träffar

Bibliografisk träff 2024-07-23

NS8593 inhibits chondrocyte ferroptosis and alleviates cartilage injury in rat adjuvant arthritis through TRPM7 / HO-1 pathway.

Hao W, Zhu R, Zhang H, Chen Y, Li S, Zhou F, Hu W, Zhou R.

Int J Biochem Cell Biol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.biocel.2024.106618

Bibliografisk träff 2024-05-16

NS8593 inhibits sodium nitroprusside-induced chondrocyte apoptosis by mediating the STING signaling pathway.

Zhu R, Hao W, Li S, Chen Y, Zhou F, Zhou R, Hu W.

Heliyon · research-article; journal article · DOI 10.1016/j.heliyon.2024.e31375

Bibliografisk träff 2020-09-23

Mapping TRPM7 Function by NS8593.

Chubanov V, Gudermann T.

Int J Mol Sci · review-article; review; journal article · DOI 10.3390/ijms21197017

Bibliografisk träff 2020-08-01

The Small Conductance Calcium-Activated Potassium Channel Inhibitors NS8593 and UCL1684 Prevent the Development of Atrial Fibrillation Through Atrial-Selective Inhibition of Sodium Channel Activity.

Burashnikov A, Barajas-Martinez H, Hu D, Robinson VM, Grunnet M, Antzelevitch C.

J Cardiovasc Pharmacol · comparative study; research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1097/fjc.0000000000000855

Bibliografisk träff 2019-10-15

NS8593 inhibits Ca<sup>2+</sup> permeant channels reversing mouse airway smooth muscle contraction.

Liu BB, Peng YB, Zhang WJ, Zhao XX, Chen LP, Liu MS, Wang GG, Liu YJ, Shen J, Zhao P, Xue L, Yu MF, Chen W, Ma LQ, Qin G, Dai J, Liu QH.

Life Sci · journal article · DOI 10.1016/j.lfs.2019.116953

Bibliografisk träff 2019-08-19

The <i>Drosophila</i> Trpm channel mediates calcium influx during egg activation.

Hu Q, Wolfner MF.

Proc Natl Acad Sci U S A · research support, non-u.s. gov't; research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1073/pnas.1906967116

Bibliografisk träff 2014-12-24

Pharmacologic inhibition of small-conductance calcium-activated potassium (SK) channels by NS8593 reveals atrial antiarrhythmic potential in horses.

Haugaard MM, Hesselkilde EZ, Pehrson S, Carstensen H, Flethøj M, Præstegaard KF, Sørensen US, Diness JG, Grunnet M, Buhl R, Jespersen T.

Heart Rhythm · research support, non-u.s. gov't; journal article · DOI 10.1016/j.hrthm.2014.12.028

Bibliografisk träff 2012-06-01

Natural and synthetic modulators of SK (K(ca)2) potassium channels inhibit magnesium-dependent activity of the kinase-coupled cation channel TRPM7.

Chubanov V, Mederos y Schnitzler M, Meißner M, Schäfer S, Abstiens K, Hofmann T, Gudermann T.

Br J Pharmacol · research support, non-u.s. gov't; research-article; journal article · DOI 10.1111/j.1476-5381.2012.01855.x

Bibliografisk träff 2011-03-01

Negative gating modulation by (R)-N-(benzimidazol-2-yl)-1,2,3,4-tetrahydro-1-naphthylamine (NS8593) depends on residues in the inner pore vestibule: pharmacological evidence of deep-pore gating of K(Ca)2 channels.

Jenkins DP, Strøbæk D, Hougaard C, Jensen ML, Hummel R, Sørensen US, Christophersen P, Wulff H.

Mol Pharmacol · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1124/mol.110.069807

Bibliografisk träff 2006-08-22

Inhibitory gating modulation of small conductance Ca2+-activated K+ channels by the synthetic compound (R)-N-(benzimidazol-2-yl)-1,2,3,4-tetrahydro-1-naphtylamine (NS8593) reduces afterhyperpolarizing current in hippocampal CA1 neurons.

Strøbaek D, Hougaard C, Johansen TH, Sørensen US, Nielsen EØ, Nielsen KS, Taylor RD, Pedarzani P, Christophersen P.

Mol Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1124/mol.106.027110