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Publikationer i urvalet

14 träffar

Bibliografisk träff 2025-02-09

Brain-penetrant histone deacetylase inhibitor RG2833 improves spatial memory in females of an Alzheimer's disease rat model.

Ndukwe K, Serrano PA, Rockwell P, Xie L, Figueiredo-Pereira ME.

J Alzheimers Dis · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1177/13872877251314777

Bibliografisk träff 2024-11-01

Correction to: Histone Deacetylase Inhibitor RGFP109 Overcomes Temozolomide Resistance by Blocking NF-κB-Dependent Transcription in Glioblastoma Cell Lines.

Li ZY, Li QZ, Chen L, Chen BD, Wang B, Zhang XJ, Li WP, Res N.

Neurochem Res · published erratum · DOI 10.1007/s11064-024-04237-2

Bibliografisk träff 2023-05-01

Epigenetic upregulation of Schlafen11 renders  WNT- and SHH-activated medulloblastomas sensitive to cisplatin.

Nakata S, Murai J, Okada M, Takahashi H, Findlay TH, Malebranche K, Parthasarathy A, Miyashita S, Gabdulkhaev R, Benkimoun I, Druillennec S, Chabi S, Hawkins E, Miyahara H, Tateishi K, Yamashita S, Yamada S, Saito T, On J, Watanabe J, Tsukamoto Y, Yoshimura J, Oishi M, Nakano T, Imamura M, Imai C, Yamamoto T, Takeshima H, Sasaki AT, Rodriguez FJ, Nobusawa S, Varlet P, Pouponnot C, Osuka S, Pommier Y, Kakita A, Fujii Y, Raabe EH, Eberhart CG, Natsumeda M.

Neuro Oncol · research support, n.i.h., intramural; research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1093/neuonc/noac243

Bibliografisk träff 2023-04-25

HDAC1 mediates epithelial-mesenchymal transition and promotes cancer cell invasion in glioblastoma.

Cheng Z, Li S, Yuan J, Li Y, Cheng S, Huang S, Dong J.

Pathol Res Pract · journal article · DOI 10.1016/j.prp.2023.154481

Bibliografisk träff 2022-09-15

Histone deacetylase 1 and 3 inhibitors alleviate colon inflammation by inhibiting Th17 cell differentiation.

Gu Z, Chen X, Zhu D, Wu S, Yu C.

J Clin Lab Anal · research-article; journal article · DOI 10.1002/jcla.24699

Bibliografisk träff 2021-11-25

Epigenetic Heterogeneity in Friedreich Ataxia Underlies Variable <i>FXN</i> Reactivation.

Rodden LN, Gilliam KM, Lam C, Lynch DR, Bidichandani SI.

Front Neurosci · research-article; journal article · DOI 10.3389/fnins.2021.752921

Bibliografisk träff 2021-06-10

LMK235, a small molecule inhibitor of HDAC4/5, protects dopaminergic neurons against neurotoxin- and α-synuclein-induced degeneration in cellular models of Parkinson's disease.

Mazzocchi M, Goulding SR, Wyatt SL, Collins LM, Sullivan AM, O'Keeffe GW.

Mol Cell Neurosci · research support, non-u.s. gov't; journal article · DOI 10.1016/j.mcn.2021.103642

Bibliografisk träff 2021-03-13

Drosophila RASopathy models identify disease subtype differences and biomarkers of drug efficacy.

Das TK, Gatto J, Mirmira R, Hourizadeh E, Kaufman D, Gelb BD, Cagan R.

iScience · research-article; journal article · DOI 10.1016/j.isci.2021.102306

Bibliografisk träff 2021-02-17

The Effects of Selective Inhibition of Histone Deacetylase 1 and 3 in Huntington's Disease Mice.

Hecklau K, Mueller S, Koch SP, Mehkary MH, Kilic B, Harms C, Boehm-Sturm P, Yildirim F.

Front Mol Neurosci · research-article; journal article · DOI 10.3389/fnmol.2021.616886

Bibliografisk träff 2020-01-03

Depending on the stress, histone deacetylase inhibitors act as heat shock protein co-inducers in motor neurons and potentiate arimoclomol, exerting neuroprotection through multiple mechanisms in ALS models.

Kuta R, Larochelle N, Fernandez M, Pal A, Minotti S, Tibshirani M, St Louis K, Gentil BJ, Nalbantoglu JN, Hermann A, Durham HD.

Cell Stress Chaperones · research support, non-u.s. gov't; research-article; journal article · DOI 10.1007/s12192-019-01064-1

Bibliografisk träff 2016-09-08

Histone Deacetylase Inhibitor RGFP109 Overcomes Temozolomide Resistance by Blocking NF-κB-Dependent Transcription in Glioblastoma Cell Lines.

Li ZY, Li QZ, Chen L, Chen BD, Wang B, Zhang XJ, Li WP.

Neurochem Res · journal article · DOI 10.1007/s11064-016-2043-5

Bibliografisk träff 2014-09-16

Epigenetic therapy for Friedreich ataxia.

Soragni E, Miao W, Iudicello M, Jacoby D, De Mercanti S, Clerico M, Longo F, Piga A, Ku S, Campau E, Du J, Penalver P, Rai M, Madara JC, Nazor K, O'Connor M, Maximov A, Loring JF, Pandolfo M, Durelli L, Gottesfeld JM, Rusche JR.

Ann Neurol · research support, non-u.s. gov't; research-article; clinical trial, phase i; randomized controlled trial; journal article; research support, n.i.h., extramural · DOI 10.1002/ana.24260

Bibliografisk träff 2012-08-14

RGFP109, a histone deacetylase inhibitor attenuates L-DOPA-induced dyskinesia in the MPTP-lesioned marmoset: a proof-of-concept study.

Johnston TH, Huot P, Damude S, Fox SH, Jones SW, Rusche JR, Brotchie JM.

Parkinsonism Relat Disord · research support, non-u.s. gov't; journal article · DOI 10.1016/j.parkreldis.2012.07.001

Bibliografisk träff 2010-01-21

Two new pimelic diphenylamide HDAC inhibitors induce sustained frataxin upregulation in cells from Friedreich's ataxia patients and in a mouse model.

Rai M, Soragni E, Chou CJ, Barnes G, Jones S, Rusche JR, Gottesfeld JM, Pandolfo M.

PLoS One · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1371/journal.pone.0008825