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Publikationer i urvalet

32 träffar

Bibliografisk träff 2025-04-02

Molecular insights into the α6β4 nicotinic acetylcholine receptor function and ligand recognition.

Su J, Yu Z, Yin Z, Zhang Z, Zhao J, Meng Y, Li R, Gao Y, Zhang H, Yu R, Zhao Y.

Nat Commun · research-article; journal article · DOI 10.1038/s41467-025-58333-0

Bibliografisk träff 2020-05-01

Countering Opioid-induced Respiratory Depression in Male Rats with Nicotinic Acetylcholine Receptor Partial Agonists Varenicline and ABT 594.

Ren J, Ding X, Greer JJ.

Anesthesiology · research support, non-u.s. gov't; journal article · DOI 10.1097/aln.0000000000003128

Bibliografisk träff 2018-10-25

Optical probing of acetylcholine receptors on neurons in the medial habenula with a novel caged nicotine drug analogue.

Passlick S, Thapaliya ER, Chen Z, Richers MT, Ellis-Davies GCR.

J Physiol · research support, non-u.s. gov't; journal article; research support, n.i.h., extramural · DOI 10.1113/jp276615

Bibliografisk träff 2018-01-13

Profiling attention and cognition enhancing drugs in a rat touchscreen-based continuous performance test.

Ding Z, Brown JW, Rueter LE, Mohler EG.

Psychopharmacology (Berl) · research support, non-u.s. gov't; journal article · DOI 10.1007/s00213-017-4827-y

Bibliografisk träff 2016-12-07

Antinociceptive effect of tebanicline for various noxious stimuli-induced behaviours in mice.

Hayashi T, Katsuyama S, Orito T, Suzuki T, Sakurada S.

Neurosci Lett · journal article · DOI 10.1016/j.neulet.2016.12.013

Bibliografisk träff 2013-08-08

Discriminative-stimulus effects of NS9283, a nicotinic α4β2* positive allosteric modulator, in nicotine-discriminating rats.

Mohler EG, Franklin SR, Rueter LE.

Psychopharmacology (Berl) · research support, non-u.s. gov't; journal article · DOI 10.1007/s00213-013-3207-5

Bibliografisk träff 2012-02-11

Population analyses of efficacy and safety of ABT-594 in subjects with diabetic peripheral neuropathic pain.

Dutta S, Hosmane BS, Awni WM.

AAPS J · clinical trial, phase ii; research support, non-u.s. gov't; research-article; multicenter study; randomized controlled trial; journal article · DOI 10.1208/s12248-012-9328-7

Bibliografisk träff 2011-12-07

Population pharmacokinetics of ABT-594 in subjects with diabetic peripheral neuropathic pain.

Dutta S, Awni W.

J Clin Pharm Ther · comparative study; multicenter study; randomized controlled trial; journal article · DOI 10.1111/j.1365-2710.2011.01325.x

Bibliografisk träff 2011-05-17

Potentiation of analgesic efficacy but not side effects: co-administration of an α4β2 neuronal nicotinic acetylcholine receptor agonist and its positive allosteric modulator in experimental models of pain in rats.

Zhu CZ, Chin CL, Rustay NR, Zhong C, Mikusa J, Chandran P, Salyers A, Gomez E, Simler G, Lewis LG, Gauvin D, Baker S, Pai M, Tovcimak A, Brown J, Komater V, Fox GB, Decker MW, Jacobson PB, Gopalakrishnan M, Lee CH, Honore P.

Biochem Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bcp.2011.05.007

Bibliografisk träff 2010-06-01

Selective potentiation of gabapentin-mediated antinociception in the rat formalin test by the nicotinic acetylcholine receptor agonist ABT-594.

Munro G, Dyhr H, Grunnet M.

Neuropharmacology · research support, non-u.s. gov't; journal article · DOI 10.1016/j.neuropharm.2010.05.010

Bibliografisk träff 2010-01-11

ABT-594 improves performance in the 5-choice serial reaction time task under conditions of increased difficulty, sub-chronic dosing, and in poorly-performing subjects.

Mohler EG, Franklin SR, Rueter LE, Fox GB, Decker MW, Browman KE.

Pharmacol Biochem Behav · journal article · DOI 10.1016/j.pbb.2009.12.019

Bibliografisk träff 2009-07-24

A randomized, double-blind, placebo-controlled trial evaluating the efficacy and safety of ABT-594 in patients with diabetic peripheral neuropathic pain.

Rowbotham MC, Duan RW, Thomas J, Nothaft W, Backonja MM.

Pain · clinical trial, phase ii; research support, non-u.s. gov't; multicenter study; randomized controlled trial; journal article · DOI 10.1016/j.pain.2009.06.013

Bibliografisk träff 2009-02-04

Preparation and characterization of N-(3-pyridinyl) spirocyclic diamines as ligands for nicotinic acetylcholine receptors.

Sippy KB, Anderson DJ, Bunnelle WH, Hutchins CW, Schrimpf MR.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2009.01.099

Bibliografisk träff 2007-12-21

Morphine and ABT-594 (a nicotinic acetylcholine agonist) exert centrally mediated antinociception in the rat cyclophosphamide cystitis model of visceral pain.

Joshi SK, Mikusa JP, Weaver B, Honore P.

J Pain · research support, non-u.s. gov't; journal article · DOI 10.1016/j.jpain.2007.09.004

Bibliografisk träff 2007-07-14

Profile of nicotinic acetylcholine receptor agonists ABT-594 and A-582941, with differential subtype selectivity, on delayed matching accuracy by young monkeys.

Buccafusco JJ, Terry AV, Decker MW, Gopalakrishnan M.

Biochem Pharmacol · research support, non-u.s. gov't; research support, u.s. gov't, non-p.h.s.; journal article · DOI 10.1016/j.bcp.2007.07.010

Bibliografisk träff 2006-01-18

Synthesis and analgesic activity of secondary amine analogues of pyridylmethylamine and positional isomeric analogues of ABT-594.

Zhang CX, Ge ZM, Cheng TM, Li RT.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2005.12.073

Bibliografisk träff 2005-11-14

Mapping brain activity following administration of a nicotinic acetylcholine receptor agonist, ABT-594, using functional magnetic resonance imaging in awake rats.

Skoubis PD, Hradil V, Chin CL, Luo Y, Fox GB, McGaraughty S.

Neuroscience · journal article · DOI 10.1016/j.neuroscience.2005.08.072

Bibliografisk träff 2005-02-01

ABT-594 (a nicotinic acetylcholine agonist): anti-allodynia in a rat chemotherapy-induced pain model.

Lynch JJ, Wade CL, Mikusa JP, Decker MW, Honore P.

Eur J Pharmacol · comparative study; journal article · DOI 10.1016/j.ejphar.2004.12.034

Bibliografisk träff 2004-11-12

Nicotinic acetylcholine receptor-mediated [3H]dopamine release from hippocampus.

Cao YJ, Surowy CS, Puttfarcken PS.

J Pharmacol Exp Ther · journal article · DOI 10.1124/jpet.104.076794

Bibliografisk träff 2003-11-01

Thermodynamic conformational analysis and structural stability of the nicotinic analgesic ABT-594.

Mora M, Muñoz-Caro C, Niño A.

J Comput Aided Mol Des · research support, non-u.s. gov't; journal article · DOI 10.1023/b:jcam.0000017485.97656.58

Bibliografisk träff 2003-05-01

Morphine vs. ABT-594: a reexamination by the principle of double effect.

Clark PA.

Linacre Q · journal article · DOI 10.1080/20508549.2003.11877668

Bibliografisk träff 2000-05-01

Analgesic profile of the nicotinic acetylcholine receptor agonists, (+)-epibatidine and ABT-594 in models of persistent inflammatory and neuropathic pain.

Kesingland AC, Gentry CT, Panesar MS, Bowes MA, Vernier JM, Cube R, Walker K, Urban L.

Pain · journal article · DOI 10.1016/s0304-3959(00)00233-5

Bibliografisk träff 2000-04-01

Analgesic and toxic effects of ABT-594 resemble epibatidine and nicotine in rats.

Boyce S, Webb JK, Shepheard SL, Russell MGN, Hill RG, Rupniak NMJ.

Pain · comparative study; journal article · DOI 10.1016/s0304-3959(99)00303-6

Bibliografisk träff 1999-12-01

The nicotinic acetylcholine receptor agonist ABT-594 increases FGF-2 expression in various rat brain regions.

Belluardo N, Mudò G, Caniglia G, Cheng Q, Blum M, Fuxe K.

Neuroreport · research support, non-u.s. gov't; journal article · DOI 10.1097/00001756-199912160-00034

Bibliografisk träff 1998-08-01

ABT-594, a novel cholinergic channel modulator, is efficacious in nerve ligation and diabetic neuropathy models of neuropathic pain.

Bannon AW, Decker MW, Kim DJ, Campbell JE, Arneric SP.

Brain Res · comparative study; journal article · DOI 10.1016/s0006-8993(98)00596-4

Bibliografisk träff 1998-07-01

Role of the nucleus raphe magnus in antinociception produced by ABT-594: immediate early gene responses possibly linked to neuronal nicotinic acetylcholine receptors on serotonergic neurons.

Bitner RS, Nikkel AL, Curzon P, Arneric SP, Bannon AW, Decker MW.

J Neurosci · research support, non-u.s. gov't; research-article; journal article · DOI 10.1523/jneurosci.18-14-05426.1998

Bibliografisk träff 1998-06-01

The role of neuronal nicotinic acetylcholine receptors in antinociception: effects of ABT-594.

Decker MW, Curzon P, Holladay MW, Nikkel AL, Bitner RS, Bannon AW, Donnelly-Roberts DL, Puttfarcken PS, Kuntzweiler TA, Briggs CA, Williams M, Arneric SP.

J Physiol Paris · review; journal article · DOI 10.1016/s0928-4257(98)80014-4

Bibliografisk träff 1998-05-01

ABT-594 [(R)-5-(2-azetidinylmethoxy)-2-chloropyridine]: a novel, orally effective analgesic acting via neuronal nicotinic acetylcholine receptors: I. In vitro characterization.

Donnelly-Roberts DL, Puttfarcken PS, Kuntzweiler TA, Briggs CA, Anderson DJ, Campbell JE, Piattoni-Kaplan M, McKenna DG, Wasicak JT, Holladay MW, Williams M, Arneric SP.

J Pharmacol Exp Ther · journal article · DOI 10.1016/s0022-3565(24)37422-1

Bibliografisk träff 1998-05-01

ABT-594 [(R)-5-(2-azetidinylmethoxy)-2-chloropyridine]: a novel, orally effective antinociceptive agent acting via neuronal nicotinic acetylcholine receptors: II. In vivo characterization.

Bannon AW, Decker MW, Curzon P, Buckley MJ, Kim DJ, Radek RJ, Lynch JK, Wasicak JT, Lin NH, Arnold WH, Holladay MW, Williams M, Arneric SP.

J Pharmacol Exp Ther · journal article · DOI 10.1016/s0022-3565(24)37423-3

Bibliografisk träff 1998-04-01

Antinociceptive effects of the novel neuronal nicotinic acetylcholine receptor agonist, ABT-594, in mice.

Decker MW, Bannon AW, Buckley MJ, Kim DJ, Holladay MW, Ryther KB, Lin NH, Wasicak JT, Williams M, Arneric SP.

Eur J Pharmacol · journal article · DOI 10.1016/s0014-2999(98)00042-9