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Publikationer i urvalet

26 träffar

Bibliografisk träff 2024-12-07

Quantification of 11 kratom alkaloids including mitragynine and its main metabolites in human plasma using LC-MS/MS.

Sempio C, Campos-Palomino J, Klawitter J, Zhao W, Huestis MA, Christians U, Klawitter J.

Anal Bioanal Chem · validation study; journal article · DOI 10.1007/s00216-024-05689-9

Bibliografisk träff 2024-11-09

Kratom Alkaloids: A Blood-Brain Barrier Specific Membrane Permeability Assay-Guided Isolation and Cyclodextrin Complexation Study.

Dohárszky A, Vági EM, Könczöl Á, Simon A, Várnagy E, Muratov M, Steiger KI, Várnai B, Béni S, Riethmüller E, Fejős I.

Molecules · research-article; journal article · DOI 10.3390/molecules29225302

Bibliografisk träff 2024-07-09

In-vitro hepatotoxic activity of mitragynine and paynantheine isolated from the leaves of Mitragyna speciosa Korth. (Kratom).

Karunakaran T, Ganasan J, Rusmadi NN, Santhanam R, Mordi MN.

Nat Prod Res · journal article · DOI 10.1080/14786419.2024.2375760

Bibliografisk träff 2024-06-06

Phytochemical analysis of water and ethanol liquid extracts prepared using freshly harvested leaves of Mitragyna speciosa (Korth.).

Karunakaran T, Vicknasingam B, Chawarski MC.

Nat Prod Res · journal article · DOI 10.1080/14786419.2024.2362428

Bibliografisk träff 2024-03-13

Paynantheine more effectively reverses multidrug resistance in malignant EPG85.257RDB and MCF7MX cells than morphine and speciociliatine.

Abdali N, Nadipour Borujeni M, Hosseini SA, Malekzadeh R, Abolhasani M, Mirzaei SA, Elahian F.

Cell Biol Int · journal article · DOI 10.1002/cbin.12152

Bibliografisk träff 2024-03-01

Testing for Kratom alkaloids in fingernail clippings - not only mitragynine.

Ameline A, Gheddar L, Arbouche N, Blanchot A, Raul JS, Kintz P.

J Pharm Biomed Anal · journal article · DOI 10.1016/j.jpba.2024.116078

Bibliografisk träff 2023-09-15

An in vitro evaluation of kratom (Mitragyna speciosa) on the catalytic activity of carboxylesterase 1 (CES1).

Melchert PW, Zhang Q, Mukhopadhyay S, Kanumuri SRR, McCurdy CR, Markowitz JS.

Chem Biol Interact · research-article; journal article · DOI 10.1016/j.cbi.2023.110715

Bibliografisk träff 2023-02-19

Seasonal and Geographic Variation in Alkaloid Content of Kratom (Mitragyna speciosa (Korth.) Havil.) from Thailand.

Sengnon N, Vonghirundecha P, Chaichan W, Juengwatanatrakul T, Onthong J, Kitprasong P, Sriwiriyajan S, Chittrakarn S, Limsuwanchote S, Wungsintaweekul J.

Plants (Basel) · research-article; journal article · DOI 10.3390/plants12040949

Bibliografisk träff 2022-04-26

Plant growth and phytoactive alkaloid synthesis in kratom [Mitragyna speciosa (Korth.)] in response to varying radiance.

Zhang M, Sharma A, León F, Avery B, Kjelgren R, McCurdy CR, Pearson BJ.

PLoS One · research-article; journal article; research support, n.i.h., extramural · DOI 10.1371/journal.pone.0259326

Bibliografisk träff 2022-04-25

Kratom (Mitragyna speciosa) Validation: Quantitative Analysis of Indole and Oxindole Alkaloids Reveals Chemotypes of Plants and Products.

Manwill PK, Flores-Bocanegra L, Khin M, Raja HA, Cech NB, Oberlies NH, Todd DA.

Planta Med · research-article; journal article · DOI 10.1055/a-1795-5876

Bibliografisk träff 2022-03-11

Clinical Pharmacokinetic Assessment of Kratom (Mitragyna speciosa), a Botanical Product with Opioid-like Effects, in Healthy Adult Participants.

Tanna RS, Nguyen JT, Hadi DL, Manwill PK, Flores-Bocanegra L, Layton ME, White JR, Cech NB, Oberlies NH, Rettie AE, Thummel KE, Paine MF.

Pharmaceutics · research-article; journal article · DOI 10.3390/pharmaceutics14030620

Bibliografisk träff 2021-11-03

Evaluation of Kratom Opioid Derivatives as Potential Treatment Option for Alcohol Use Disorder.

Gutridge AM, Chakraborty S, Varga BR, Rhoda ES, French AR, Blaine AT, Royer QH, Cui H, Yuan J, Cassell RJ, Szabó M, Majumdar S, van Rijn RM.

Front Pharmacol · research-article; journal article · DOI 10.3389/fphar.2021.764885

Bibliografisk träff 2021-09-01

Activity of Mitragyna speciosa ("Kratom") Alkaloids at Serotonin Receptors.

León F, Obeng S, Mottinelli M, Chen Y, King TI, Berthold EC, Kamble SH, Restrepo LF, Patel A, Gamez-Jimenez LR, Lopera-Londoño C, Hiranita T, Sharma A, Hampson AJ, Canal CE, McMahon LR, McCurdy CR.

J Med Chem · research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/acs.jmedchem.1c00726

Bibliografisk träff 2021-08-13

Rapid spheroid assays in a 3-dimensional cell culture chip.

Teh JL, Abdul Rahman SF, Domnic G, Satiyasilan L, Chear NJY, Singh D, Mohana-Kumaran N.

BMC Res Notes · brief-report; journal article · DOI 10.1186/s13104-021-05727-0

Bibliografisk träff 2021-07-02

Combinations of indole based alkaloids from Mitragyna speciosa (Kratom) and cisplatin inhibit cell proliferation and migration of nasopharyngeal carcinoma cell lines.

Domnic G, Jeng-Yeou Chear N, Abdul Rahman SF, Ramanathan S, Lo KW, Singh D, Mohana-Kumaran N.

J Ethnopharmacol · journal article · DOI 10.1016/j.jep.2021.114391

Bibliografisk träff 2021-06-17

Accelerated Solvent Extractions (ASE) of Mitragyna speciosa Korth. (Kratom) Leaves: Evaluation of Its Cytotoxicity and Antinociceptive Activity.

Goh YS, Karunakaran T, Murugaiyah V, Santhanam R, Abu Bakar MH, Ramanathan S.

Molecules · research-article; journal article · DOI 10.3390/molecules26123704

Bibliografisk träff 2021-02-23

Pharmacokinetics of Eleven Kratom Alkaloids Following an Oral Dose of Either Traditional or Commercial Kratom Products in Rats.

Kamble SH, Berthold EC, King TI, Raju Kanumuri SR, Popa R, Herting JR, León F, Sharma A, McMahon LR, Avery BA, McCurdy CR.

J Nat Prod · research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/acs.jnatprod.0c01163

Bibliografisk träff 2020-05-01

Temperature and pH-Dependent Stability of Mitragyna Alkaloids.

Basiliere S, Kerrigan S.

J Anal Toxicol · journal article · DOI 10.1093/jat/bkz103

Bibliografisk träff 2020-04-14

Development of an ELISA for detection of mitragynine and its metabolites in human urine.

Lee MJ, Ramanathan S, Mansor SM, Tan SC.

Anal Biochem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ab.2020.113733

Bibliografisk träff 2019-11-07

Exploration of cytochrome P450 inhibition mediated drug-drug interaction potential of kratom alkaloids.

Kamble SH, Sharma A, King TI, Berthold EC, León F, Meyer PKL, Kanumuri SRR, McMahon LR, McCurdy CR, Avery BA.

Toxicol Lett · research-article; journal article · DOI 10.1016/j.toxlet.2019.11.005

Bibliografisk träff 2019-05-15

Simultaneous quantification of ten key Kratom alkaloids in Mitragyna speciosa leaf extracts and commercial products by ultra-performance liquid chromatography-tandem mass spectrometry.

Sharma A, Kamble SH, León F, Chear NJ, King TI, Berthold EC, Ramanathan S, McCurdy CR, Avery BA.

Drug Test Anal · research-article; journal article · DOI 10.1002/dta.2604

Bibliografisk träff 2018-02-13

Identification of five Mitragyna alkaloids in urine using liquid chromatography-quadrupole/time of flight mass spectrometry.

Basiliere S, Bryand K, Kerrigan S.

J Chromatogr B Analyt Technol Biomed Life Sci · journal article · DOI 10.1016/j.jchromb.2018.02.010

Bibliografisk träff 2014-08-21

Development of indirect competitive ELISA for quantification of mitragynine in Kratom (Mitragyna speciosa (Roxb.) Korth.).

Limsuwanchote S, Wungsintaweekul J, Keawpradub N, Putalun W, Morimoto S, Tanaka H.

Forensic Sci Int · research support, non-u.s. gov't; journal article · DOI 10.1016/j.forsciint.2014.08.011

Bibliografisk träff 2012-12-01

Total syntheses of mitragynine, paynantheine and speciogynine via an enantioselective thiourea-catalysed Pictet-Spengler reaction.

Kerschgens IP, Claveau E, Wanner MJ, Ingemann S, van Maarseveen JH, Hiemstra H.

Chem Commun (Camb) · research support, non-u.s. gov't; journal article · DOI 10.1039/c2cc37023a

Bibliografisk träff 2011-03-29

Metabolism studies of the Kratom alkaloids mitraciliatine and isopaynantheine, diastereomers of the main alkaloids mitragynine and paynantheine, in rat and human urine using liquid chromatography-linear ion trap-mass spectrometry.

Philipp AA, Wissenbach DK, Weber AA, Zapp J, Maurer HH.

J Chromatogr B Analyt Technol Biomed Life Sci · journal article · DOI 10.1016/j.jchromb.2011.03.005

Bibliografisk träff 2009-11-10

Use of liquid chromatography coupled to low- and high-resolution linear ion trap mass spectrometry for studying the metabolism of paynantheine, an alkaloid of the herbal drug Kratom in rat and human urine.

Philipp AA, Wissenbach DK, Weber AA, Zapp J, Zoerntlein SW, Kanogsunthornrat J, Maurer HH.

Anal Bioanal Chem · journal article · DOI 10.1007/s00216-009-3239-1

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Publikationer i urvalet

Quantification of 11 kratom alkaloids including mitragynine and its main metabolites in human plasma using LC-MS/MS.

Kratom Alkaloids: A Blood-Brain Barrier Specific Membrane Permeability Assay-Guided Isolation and Cyclodextrin Complexation Study.

<i>In-vitro</i> hepatotoxic activity of mitragynine and paynantheine isolated from the leaves of <i>Mitragyna speciosa</i> Korth. (Kratom).

Phytochemical analysis of water and ethanol liquid extracts prepared using freshly harvested leaves of <i>Mitragyna speciosa</i> (Korth.).

Paynantheine more effectively reverses multidrug resistance in malignant EPG85.257RDB and MCF7MX cells than morphine and speciociliatine.

Testing for Kratom alkaloids in fingernail clippings - not only mitragynine.

An in vitro evaluation of kratom (Mitragyna speciosa) on the catalytic activity of carboxylesterase 1 (CES1).

Seasonal and Geographic Variation in Alkaloid Content of Kratom (<i>Mitragyna speciosa</i> (Korth.) Havil.) from Thailand.

Plant growth and phytoactive alkaloid synthesis in kratom [Mitragyna speciosa (Korth.)] in response to varying radiance.

Kratom (Mitragyna speciosa) Validation: Quantitative Analysis of Indole and Oxindole Alkaloids Reveals Chemotypes of Plants and Products.

Clinical Pharmacokinetic Assessment of Kratom (<i>Mitragyna speciosa</i>), a Botanical Product with Opioid-like Effects, in Healthy Adult Participants.

Evaluation of Kratom Opioid Derivatives as Potential Treatment Option for Alcohol Use Disorder.

Activity of <i>Mitragyna speciosa</i> ("Kratom") Alkaloids at Serotonin Receptors.

Rapid spheroid assays in a 3-dimensional cell culture chip.

Combinations of indole based alkaloids from Mitragyna speciosa (Kratom) and cisplatin inhibit cell proliferation and migration of nasopharyngeal carcinoma cell lines.

Accelerated Solvent Extractions (ASE) of <i>Mitragyna speciosa</i> Korth. (Kratom) Leaves: Evaluation of Its Cytotoxicity and Antinociceptive Activity.

Pharmacokinetics of Eleven Kratom Alkaloids Following an Oral Dose of Either Traditional or Commercial Kratom Products in Rats.

Temperature and pH-Dependent Stability of Mitragyna Alkaloids.

Development of an ELISA for detection of mitragynine and its metabolites in human urine.

Exploration of cytochrome P450 inhibition mediated drug-drug interaction potential of kratom alkaloids.

Simultaneous quantification of ten key Kratom alkaloids in Mitragyna speciosa leaf extracts and commercial products by ultra-performance liquid chromatography-tandem mass spectrometry.

Identification of five Mitragyna alkaloids in urine using liquid chromatography-quadrupole/time of flight mass spectrometry.

Development of indirect competitive ELISA for quantification of mitragynine in Kratom (Mitragyna speciosa (Roxb.) Korth.).

Total syntheses of mitragynine, paynantheine and speciogynine via an enantioselective thiourea-catalysed Pictet-Spengler reaction.

Metabolism studies of the Kratom alkaloids mitraciliatine and isopaynantheine, diastereomers of the main alkaloids mitragynine and paynantheine, in rat and human urine using liquid chromatography-linear ion trap-mass spectrometry.

Use of liquid chromatography coupled to low- and high-resolution linear ion trap mass spectrometry for studying the metabolism of paynantheine, an alkaloid of the herbal drug Kratom in rat and human urine.