Dual NADPH oxidases DUOX1 and DUOX2 synthesize NAADP and are necessary for Ca<sup>2+</sup> signaling during T cell activation.
Gu F, Krüger A, Roggenkamp HG, Alpers R, Lodygin D, Jaquet V, Möckl F, Hernandez C LC, Winterberg K, Bauche A, Rosche A, Grasberger H, Kao JY, Schetelig D, Werner R, Schröder K, Carty M, Bowie AG, Huber S, Meier C, Mittrücker HW, Heeren J, Krause KH, Flügel A, Diercks BP, Guse AH.
Sci Signal · research support, non-u.s. gov't; journal article; research support, n.i.h., extramural · DOI 10.1126/scisignal.abe3800