The induction mechanism of the flavonoid-responsive regulator FrrA.
Werner N, Werten S, Hoppen J, Palm GJ, Göttfert M, Hinrichs W.
FEBS J · journal article · DOI 10.1111/febs.16141 PUBLIKATIONSREGISTRET
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Publikationer i urvalet
32 träffarStructural basis for inhibition of 17β-hydroxysteroid dehydrogenases by phytoestrogens: The case of fungal 17β-HSDcl.
Cassetta A, Stojan J, Krastanova I, Kristan K, Brunskole Švegelj M, Lamba D, Lanišnik Rižner T.
J Steroid Biochem Mol Biol · journal article · DOI 10.1016/j.jsbmb.2017.02.020Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells.
Keller AN, Eckle SB, Xu W, Liu L, Hughes VA, Mak JY, Meehan BS, Pediongco T, Birkinshaw RW, Chen Z, Wang H, D'Souza C, Kjer-Nielsen L, Gherardin NA, Godfrey DI, Kostenko L, Corbett AJ, Purcell AW, Fairlie DP, McCluskey J, Rossjohn J.
Nat Immunol · research support, non-u.s. gov't; journal article · DOI 10.1038/ni.3679Structural Insight into the Interactions between Death-Associated Protein Kinase 1 and Natural Flavonoids.
Yokoyama T, Kosaka Y, Mizuguchi M.
J Med Chem · journal article · DOI 10.1021/acs.jmedchem.5b00893Genistein from Vigna angularis Extends Lifespan in Caenorhabditis elegans.
Lee EB, Ahn D, Kim BJ, Lee SY, Seo HW, Cha YS, Jeon H, Eun JS, Cha DS, Kim DK.
Biomol Ther (Seoul) · research-article; journal article · DOI 10.4062/biomolther.2014.075Genistein exhibits anti-cancer effects via down-regulating FoxM1 in H446 small-cell lung cancer cells.
Tian T, Li J, Li B, Wang Y, Li M, Ma D, Wang X.
Tumour Biol · research support, non-u.s. gov't; journal article · DOI 10.1007/s13277-013-1542-0Genistein attenuates cancer stem cell characteristics in gastric cancer through the downregulation of Gli1.
Yu D, Shin HS, Lee YS, Lee D, Kim S, Lee YC.
Oncol Rep · research support, non-u.s. gov't; journal article · DOI 10.3892/or.2013.2893The human urine metabolome.
Bouatra S, Aziat F, Mandal R, Guo AC, Wilson MR, Knox C, Bjorndahl TC, Krishnamurthy R, Saleem F, Liu P, Dame ZT, Poelzer J, Huynh J, Yallou FS, Psychogios N, Dong E, Bogumil R, Roehring C, Wishart DS.
PLoS One · research support, non-u.s. gov't; research-article; journal article · DOI 10.1371/journal.pone.0073076Design and optimization of a novel method for extraction of genistein.
Pandit NT, Patravale VB.
Indian J Pharm Sci · research-article; journal article · DOI 10.4103/0250-474x.91583Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: implications to tetramer stability and ligand-binding.
Trivella DB, Bleicher L, Palmieri Lde C, Wiggers HJ, Montanari CA, Kelly JW, Lima LM, Foguel D, Polikarpov I.
J Struct Biol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.jsb.2010.03.002Genistein suppresses adipogenesis of 3T3-L1 cells via multiple signal pathways.
Zhang M, Ikeda K, Xu JW, Yamori Y, Gao XM, Zhang BL.
Phytother Res · research support, non-u.s. gov't; journal article · DOI 10.1002/ptr.2724Genistein, a soybean isoflavone, reduces the production of pro-inflammatory and adhesion molecules induced by hemolysate in brain microvascular endothelial cells.
Lu H, Shi JX, Zhang DM, Chen HL, Qi M, Yin HX.
Acta Neurol Belg · research support, non-u.s. gov't; journal articlePhytoestrogens and breast cancer: a complex story.
Helferich WG, Andrade JE, Hoagland MS.
Inflammopharmacology · review; journal article · DOI 10.1007/s10787-008-8020-0Genistein inhibits rat aortic smooth muscle cell proliferation through the induction of p27kip1.
Yu JY, Lee JJ, Lim Y, Kim TJ, Jin YR, Sheen YY, Yun YP.
J Pharmacol Sci · research support, non-u.s. gov't; journal article · DOI 10.1254/jphs.08001fpGenistein induces the p21WAF1/CIP1 and p16INK4a tumor suppressor genes in prostate cancer cells by epigenetic mechanisms involving active chromatin modification.
Majid S, Kikuno N, Nelles J, Noonan E, Tanaka Y, Kawamoto K, Hirata H, Li LC, Zhao H, Okino ST, Place RF, Pookot D, Dahiya R.
Cancer Res · research support, non-u.s. gov't; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1158/0008-5472.can-07-2290NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses.
Nettles KW, Bruning JB, Gil G, Nowak J, Sharma SK, Sharma SK, Hahm JB, Kulp K, Hochberg RB, Zhou H, Katzenellenbogen JA, Katzenellenbogen BS, Kim Y, Joachmiak A, Greene GL.
Nat Chem Biol · comparative study; research support, non-u.s. gov't; research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1038/nchembio.76Phytochemical genistein in the regulation of vascular function: new insights.
Si H, Liu D.
Curr Med Chem · research support, non-u.s. gov't; review; journal article · DOI 10.2174/092986707782023325Sulfation of the isoflavones genistein and daidzein in human and rat liver and gastrointestinal tract.
Ronis MJ, Little JM, Barone GW, Chen G, Radominska-Pandya A, Badger TM.
J Med Food · research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1089/jmf.2006.9.348Genistein, a dietary isoflavone, down-regulates the MDM2 oncogene at both transcriptional and posttranslational levels.
Li M, Zhang Z, Hill DL, Chen X, Wang H, Zhang R.
Cancer Res · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1158/0008-5472.can-05-1302Inactivation of nuclear factor kappaB by soy isoflavone genistein contributes to increased apoptosis induced by chemotherapeutic agents in human cancer cells.
Li Y, Ahmed F, Ali S, Philip PA, Kucuk O, Sarkar FH.
Cancer Res · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article; research support, n.i.h., extramural · DOI 10.1158/0008-5472.can-04-4604Influence of dietary genistein levels on tissue genistein deposition and on the physical, chemical, and sensory quality of rainbow trout, Oncorhynchus mykiss.
D'Souza N, Skonberg DI, Camire ME, Guthrie KE, Malison J, Lima L.
J Agric Food Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jf0484024Genistein inhibits p38 map kinase activation, matrix metalloproteinase type 2, and cell invasion in human prostate epithelial cells.
Huang X, Chen S, Xu L, Liu Y, Deb DK, Platanias LC, Bergan RC.
Cancer Res · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article; research support, n.i.h., extramural · DOI 10.1158/0008-5472.can-04-2807Effects of the phytoestrogen genistein on cardiovascular risk factors in postmenopausal women.
Crisafulli A, Altavilla D, Marini H, Bitto A, Cucinotta D, Frisina N, Corrado F, D'Anna R, Squadrito G, Adamo EB, Marini R, Romeo A, Cancellieri F, Buemi M, Squadrito F.
Menopause · clinical trial; randomized controlled trial; journal article · DOI 10.1097/00042192-200512020-00013Understanding the selectivity of genistein for human estrogen receptor-beta using X-ray crystallography and computational methods.
Manas ES, Xu ZB, Unwalla RJ, Somers WS.
Structure · journal article · DOI 10.1016/j.str.2004.09.015The soy isoflavone, genistein, protects human cortical neuronal cells from oxidative stress.
Sonee M, Sum T, Wang C, Mukherjee SK.
Neurotoxicology · research support, non-u.s. gov't; research support, u.s. gov't, non-p.h.s.; journal article · DOI 10.1016/j.neuro.2003.11.001Genistein enhances expression of genes involved in fatty acid catabolism through activation of PPARalpha.
Kim S, Shin HJ, Kim SY, Kim JH, Lee YS, Kim DH, Lee MO.
Mol Cell Endocrinol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.mce.2004.03.011Genistein administration decreases serum corticosterone and testosterone levels in rats.
Ohno S, Nakajima Y, Inoue K, Nakazawa H, Nakajin S.
Life Sci · research support, non-u.s. gov't; journal article · DOI 10.1016/j.lfs.2003.04.006Exposure to genistein during gestation and lactation demasculinizes the reproductive system in rats.
Wisniewski AB, Klein SL, Lakshmanan Y, Gearhart JP.
J Urol · comparative study; research support, u.s. gov't, p.h.s.; journal article · DOI 10.1097/01.ju.0000046780.23389.e0Genistein, a soybean isoflavone, inhibits inward rectifier K(+) channels in rat osteoclasts.
Okamoto F, Okabe K, Kajiya H.
Jpn J Physiol · research support, non-u.s. gov't; journal article · DOI 10.2170/jjphysiol.51.501p21CIP1 is dispensable for the G2 arrest caused by genistein in human melanoma cells.
Casagrande F, Darbon JM.
Exp Cell Res · research support, non-u.s. gov't; journal article · DOI 10.1006/excr.2000.4914