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Publikationer i urvalet

50 träffar

Bibliografisk träff 2012-09-24

Synthesis and structure-activity relationship of berberine analogues in LDLR up-regulation and AMPK activation.

Wang YX, Kong WJ, Li YH, Tang S, Li Z, Li YB, Shan YQ, Bi CW, Jiang JD, Song DQ.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2012.09.029

Bibliografisk träff 2011-11-17

Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery.

Meister S, Plouffe DM, Kuhen KL, Bonamy GM, Wu T, Barnes SW, Bopp SE, Borboa R, Bright AT, Che J, Cohen S, Dharia NV, Gagaring K, Gettayacamin M, Gordon P, Groessl T, Kato N, Lee MC, McNamara CW, Fidock DA, Nagle A, Nam TG, Richmond W, Roland J, Rottmann M, Zhou B, Froissard P, Glynne RJ, Mazier D, Sattabongkot J, Schultz PG, Tuntland T, Walker JR, Zhou Y, Chatterjee A, Diagana TT, Winzeler EA.

Science · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1126/science.1211936

Bibliografisk träff 2011-10-08

Benzenediol-berberine hybrids: multifunctional agents for Alzheimer's disease.

Jiang H, Wang X, Huang L, Luo Z, Su T, Ding K, Ding K, Li X.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2011.09.040

Bibliografisk träff 2011-04-17

Selective cholinesterase inhibition by lanostane triterpenes from fruiting bodies of Ganoderma lucidum.

Lee I, Ahn B, Choi J, Hattori M, Min B, Bae K.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2011.04.042

Bibliografisk träff 2011-03-14

Differential gene expression in rat vascular smooth muscle cells following treatment with coptisine exerts a selective antiproliferative effect.

Suzuki H, Tanabe H, Mizukami H, Inoue M.

J Nat Prod · journal article · DOI 10.1021/np100645d

Bibliografisk träff 2011-02-22

Quinolino-benzo-[5, 6]-dihydroisoquindolium compounds derived from berberine: a new class of highly selective ligands for G-quadruplex DNA in c-myc oncogene.

Ma Y, Ou TM, Tan JH, Hou JQ, Huang SL, Gu LQ, Huang ZS.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2011.02.020

Bibliografisk träff 2011-02-18

Synthesis, biological evaluation and molecular modeling of novel triazole-containing berberine derivatives as acetylcholinesterase and β-amyloid aggregation inhibitors.

Shi A, Huang L, Lu C, He F, Li X.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2011.02.025

Bibliografisk träff 2011-01-21

Synthesis of 9-substituted derivatives of berberine as anti-HIV agents.

Bodiwala HS, Sabde S, Mitra D, Bhutani KK, Singh IP.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2011.01.016

Bibliografisk träff 2010-09-15

Berberine derivatives, with substituted amino groups linked at the 9-position, as inhibitors of acetylcholinesterase/butyrylcholinesterase.

Huang L, Luo Z, He F, Shi A, Qin F, Li X.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2010.09.013

Bibliografisk träff 2010-08-10

Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.

Puri N, Prakash O, Manoharlal R, Sharma M, Ghosh I, Prasad R.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2010.07.050

Bibliografisk träff 2010-07-30

Design, synthesis, and cholesterol-lowering efficacy for prodrugs of berberrubine.

Li YH, Li Y, Yang P, Kong WJ, You XF, Ren G, Deng HB, Wang YM, Wang YX, Jiang JD, Song DQ.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2010.06.106

Bibliografisk träff 2010-06-12

Benzylisoquinoline alkaloids from the tubers of Corydalis ternata and their cytotoxicity.

Kim KH, Lee IK, Piao CJ, Choi SU, Lee JH, Kim YS, Lee KR.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2010.06.035

Bibliografisk träff 2010-05-24

Berberine-INF55 (5-nitro-2-phenylindole) hybrid antimicrobials: effects of varying the relative orientation of the berberine and INF55 components.

Tomkiewicz D, Casadei G, Larkins-Ford J, Moy TI, Garner J, Bremner JB, Ausubel FM, Lewis K, Kelso MJ.

Antimicrob Agents Chemother · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1128/aac.01715-09

Bibliografisk träff 2010-05-01

Inhibitors of prolyl oligopeptidases for the therapy of human diseases: defining diseases and inhibitors.

Lawandi J, Gerber-Lemaire S, Juillerat-Jeanneret L, Moitessier N.

J Med Chem · research support, non-u.s. gov't; review; journal article · DOI 10.1021/jm901104g

Bibliografisk träff 2010-04-27

Synthesis and biological evaluation of a new series of berberine derivatives as dual inhibitors of acetylcholinesterase and butyrylcholinesterase.

Huang L, Luo Z, He F, Lu J, Li X.

Bioorg Med Chem · journal article · DOI 10.1016/j.bmc.2010.04.063

Bibliografisk träff 2010-03-01

Membrane transporters in drug development.

International Transporter Consortium, Giacomini KM, Huang SM, Tweedie DJ, Benet LZ, Brouwer KL, Chu X, Dahlin A, Evers R, Fischer V, Hillgren KM, Hoffmaster KA, Ishikawa T, Keppler D, Kim RB, Lee CA, Niemi M, Polli JW, Sugiyama Y, Swaan PW, Ware JA, Wright SH, Yee SW, Zamek-Gliszczynski MJ, Zhang L.

Nat Rev Drug Discov · research-article; review; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1038/nrd3028

Bibliografisk träff 2010-02-14

Synthesis, anticancer and antioxidant activities of 7-methoxyisoflavanone and 2,3-diarylchromanones.

Kanagalakshmi K, Premanathan M, Priyanka R, Hemalatha B, Vanangamudi A.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2010.02.028

Bibliografisk träff 2009-12-16

Synthesis, biological evaluation, and molecular modeling of berberine derivatives as potent acetylcholinesterase inhibitors.

Huang L, Shi A, He F, Li X.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2009.12.035

Bibliografisk träff 2009-09-19

Synthesis and biological evaluation of berberine analogues as novel up-regulators for both low-density-lipoprotein receptor and insulin receptor.

Wang YX, Wang YP, Zhang H, Kong WJ, Li YH, Liu F, Gao RM, Liu T, Jiang JD, Song DQ.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2009.09.059

Bibliografisk träff 2009-08-13

Structure-activity relationship of isoform selective inhibitors of Rac1/1b GTPase nucleotide binding.

Beausoleil E, Chauvignac C, Taverne T, Lacombe S, Pognante L, Leblond B, Pallares D, Oliveira CD, Bachelot F, Carton R, Peillon H, Coutadeur S, Picard V, Lambeng N, Désiré L, Schweighoffer F.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2009.08.037

Bibliografisk träff 2009-05-14

Synthesis and evaluation of 9-O-substituted berberine derivatives containing aza-aromatic terminal group as highly selective telomeric G-quadruplex stabilizing ligands.

Ma Y, Ou TM, Tan JH, Hou JQ, Huang SL, Gu LQ, Huang ZS.

Bioorg Med Chem Lett · research support, non-u.s. gov't; research support, u.s. gov't, non-p.h.s.; journal article · DOI 10.1016/j.bmcl.2009.05.030

Bibliografisk träff 2009-04-19

Antibacterial activity of berberine-NorA pump inhibitor hybrids with a methylene ether linking group.

Samosorn S, Tanwirat B, Muhamad N, Casadei G, Tomkiewicz D, Lewis K, Suksamrarn A, Prammananan T, Gornall KC, Beck JL, Bremner JB.

Bioorg Med Chem · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.bmc.2009.04.028

Bibliografisk träff 2009-02-13

Probing of the cis-5-phenyl proline scaffold as a platform for the synthesis of mechanism-based inhibitors of the Staphylococcus aureus sortase SrtA isoform.

Kudryavtsev KV, Bentley ML, McCafferty DG.

Bioorg Med Chem · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.bmc.2009.02.008

Bibliografisk träff 2009-01-01

Berberine analogues as a novel class of the low-density-lipoprotein receptor up-regulators: synthesis, structure-activity relationships, and cholesterol-lowering efficacy.

Li YH, Yang P, Kong WJ, Wang YX, Hu CQ, Zuo ZY, Wang YM, Gao H, Gao LM, Feng YC, Du NN, Liu Y, Song DQ, Jiang JD.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm801157z

Bibliografisk träff 2008-11-27

Synthesis and structure-activity relationships of novel, substituted 5,6-dihydrodibenzo[a,g]quinolizinium P2X7 antagonists.

Lee GE, Lee HS, Lee SD, Kim JH, Kim WK, Kim YC.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2008.11.088

Bibliografisk träff 2008-07-18

9-N-Substituted berberine derivatives: stabilization of G-quadruplex DNA and down-regulation of oncogene c-myc.

Ma Y, Ou TM, Hou JQ, Lu YJ, Tan JH, Gu LQ, Huang ZS.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2008.07.029

Bibliografisk träff 2008-07-09

Synthesis and structure-activity relationships of berberine analogues as a novel class of low-density-lipoprotein receptor up-regulators.

Yang P, Song DQ, Li YH, Kong WJ, Wang YX, Gao LM, Liu SY, Cao RQ, Jiang JD.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2008.07.005

Bibliografisk träff 2008-07-02

Structure-activity relationships of 2-aryl-1H-indole inhibitors of the NorA efflux pump in Staphylococcus aureus.

Ambrus JI, Kelso MJ, Bremner JB, Ball AR, Casadei G, Lewis K.

Bioorg Med Chem Lett · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.bmcl.2008.06.093

Bibliografisk träff 2008-06-30

Functional cloning and characterization of the multidrug efflux pumps NorM from Neisseria gonorrhoeae and YdhE from Escherichia coli.

Long F, Rouquette-Loughlin C, Shafer WM, Yu EW.

Antimicrob Agents Chemother · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1128/aac.00475-08

Bibliografisk träff 2008-06-25

In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen.

Plouffe D, Brinker A, McNamara C, Henson K, Kato N, Kuhen K, Nagle A, Adrián F, Matzen JT, Anderson P, Nam TG, Gray NS, Chatterjee A, Janes J, Yan SF, Trager R, Caldwell JS, Schultz PG, Zhou Y, Winzeler EA.

Proc Natl Acad Sci U S A · research support, non-u.s. gov't; research-article; journal article · DOI 10.1073/pnas.0802982105