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Publikationer i urvalet

12 träffar

Bibliografisk träff 2023-07-19

A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.

Sutherland JJ, Yonchev D, Fekete A, Urban L.

Nat Commun · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/s41467-023-40064-9

Bibliografisk träff 2017-03-16

Recent updates of carbapenem antibiotics.

El-Gamal MI, Brahim I, Hisham N, Aladdin R, Mohammed H, Bahaaeldin A.

Eur J Med Chem · review; journal article · DOI 10.1016/j.ejmech.2017.03.022

Bibliografisk träff 2013-08-16

A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.

Morgan RE, van Staden CJ, Chen Y, Kalyanaraman N, Kalanzi J, Dunn RT, Afshari CA, Hamadeh HK.

Toxicol Sci · journal article · DOI 10.1093/toxsci/kft176

Bibliografisk träff 2013-04-09

Structure-based identification of OATP1B1/3 inhibitors.

De Bruyn T, van Westen GJ, Ijzerman AP, Stieger B, de Witte P, Augustijns PF, Annaert PP.

Mol Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1124/mol.112.084152

Bibliografisk träff 2011-04-28

Elucidation of common pharmacophores from analysis of targeted metabolites transported by the multispecific drug transporter-Organic anion transporter1 (Oat1).

Kouznetsova VL, Tsigelny IF, Nagle MA, Nigam SK.

Bioorg Med Chem · research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.bmc.2011.04.045

Bibliografisk träff 2010-09-09

Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.

Morgan RE, Trauner M, van Staden CJ, Lee PH, Ramachandran B, Eschenberg M, Afshari CA, Qualls CW, Lightfoot-Dunn R, Hamadeh HK.

Toxicol Sci · journal article · DOI 10.1093/toxsci/kfq269

Bibliografisk träff 2008-04-21

Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.

Obach RS, Lombardo F, Waters NJ.

Drug Metab Dispos · journal article · DOI 10.1124/dmd.108.020479

Bibliografisk träff 2005-07-01

Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.

Jolivette LJ, Ward KW.

J Pharm Sci · comparative study; journal article · DOI 10.1002/jps.20373

Bibliografisk träff 2004-02-01

Interactions of human- and rat-organic anion transporters with pravastatin and cimetidine.

Khamdang S, Takeda M, Shimoda M, Noshiro R, Narikawa S, Huang XL, Enomoto A, Piyachaturawat P, Endou H.

J Pharmacol Sci · comparative study; research support, non-u.s. gov't; journal article · DOI 10.1254/jphs.94.197

Bibliografisk träff 2002-06-01

Interaction of human organic anion transporters 2 and 4 with organic anion transport inhibitors.

Enomoto A, Takeda M, Shimoda M, Narikawa S, Kobayashi Y, Kobayashi Y, Yamamoto T, Sekine T, Cha SH, Niwa T, Endou H.

J Pharmacol Exp Ther · comparative study; research support, non-u.s. gov't; journal article · DOI 10.1124/jpet.301.3.797

Bibliografisk träff 2001-05-01

Characterization of organic anion transport inhibitors using cells stably expressing human organic anion transporters.

Takeda M, Narikawa S, Hosoyamada M, Cha SH, Sekine T, Endou H.

Eur J Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1016/s0014-2999(01)00962-1

Bibliografisk träff 2000-10-01

Nonsteroidal anti-inflammatory drugs efficiently reduce the transport and cytotoxicity of adefovir mediated by the human renal organic anion transporter 1.

Mulato AS, Ho ES, Cihlar T.

J Pharmacol Exp Ther · journal article · DOI 10.1016/s0022-3565(24)38862-7