Structure and function of SARS-CoV and SARS-CoV-2 main proteases and their inhibition: A comprehensive review.
Li X, Song Y.
Eur J Med Chem · research-article; review; journal article · DOI 10.1016/j.ejmech.2023.115772 PUBLIKATIONSREGISTRET
Gå till forskningen.
Publikationsdata från Europe PMC och PubMed. Följ källhänvisningar från ämnesregistret till originalpublikationerna.
Publikationer som ChEBI hänvisar till för Carmofur. Visa hela publikationsregistret
En publikationsträff är inte en slutsats. Publikationslistan visar bibliografiska uppgifter. Eventuella forskningsutdrag visas separat med originalunderlag. En källhänvisning visar inte i sig effekt, dosering eller säkerhet.
Publikationer i urvalet
17 träffarDiscovery of antiviral SARS-CoV-2 main protease inhibitors by structure-guided hit-to-lead optimization of carmofur.
Kang KM, Jang Y, Lee SS, Jin MS, Jun CD, Kim M, Kim YC.
Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2023.115720A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.
Sutherland JJ, Yonchev D, Fekete A, Urban L.
Nat Commun · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/s41467-023-40064-9The research progress of SARS-CoV-2 main protease inhibitors from 2020 to 2022.
Pang X, Xu W, Liu Y, Li H, Chen L.
Eur J Med Chem · review-article; review; journal article · DOI 10.1016/j.ejmech.2023.115491Structure-Guided Discovery of the Novel Covalent Allosteric Site and Covalent Inhibitors of Fructose-1,6-Bisphosphate Aldolase to Overcome the Azole Resistance of <i>Candidiasis</i>.
Wen W, Cao H, Huang Y, Tu J, Wan C, Wan J, Han X, Chen H, Liu J, Rao L, Su C, Peng C, Sheng C, Ren Y.
J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jmedchem.1c02102A review of the latest research on M<sup>pro</sup> targeting SARS-COV inhibitors.
Yang H, Yang J.
RSC Med Chem · review-article; review; journal article · DOI 10.1039/d1md00066gThe race to treat COVID-19: Potential therapeutic agents for the prevention and treatment of SARS-CoV-2.
Shagufta, Ahmad I.
Eur J Med Chem · review-article; review; journal article · DOI 10.1016/j.ejmech.2021.113157Design, Synthesis, and Biological Evaluation of a Series of Oxazolone Carboxamides as a Novel Class of Acid Ceramidase Inhibitors.
Caputo S, Di Martino S, Cilibrasi V, Tardia P, Mazzonna M, Russo D, Penna I, Summa M, Bertozzi SM, Realini N, Margaroli N, Migliore M, Ottonello G, Liu M, Lansbury P, Armirotti A, Bertorelli R, Ray SS, Skerlj R, Scarpelli R.
J Med Chem · research support, non-u.s. gov't; research-article; journal article · DOI 10.1021/acs.jmedchem.0c01561Protease targeted COVID-19 drug discovery and its challenges: Insight into viral main protease (Mpro) and papain-like protease (PLpro) inhibitors.
Amin SA, Banerjee S, Ghosh K, Gayen S, Jha T.
Bioorg Med Chem · research support, non-u.s. gov't; research-article; review; journal article · DOI 10.1016/j.bmc.2020.115860COVID-19 therapy: What weapons do we bring into battle?
de Almeida SMV, Santos Soares JC, Dos Santos KL, Alves JEF, Ribeiro AG, Jacob ÍTT, da Silva Ferreira CJ, Dos Santos JC, de Oliveira JF, de Carvalho Junior LB, de Lima MDCA.
Bioorg Med Chem · research support, non-u.s. gov't; research-article; journal article · DOI 10.1016/j.bmc.2020.115757COVID-19: Drug Targets and Potential Treatments.
Gil C, Ginex T, Maestro I, Nozal V, Barrado-Gil L, Cuesta-Geijo MÁ, Urquiza J, Ramírez D, Alonso C, Campillo NE, Martinez A.
J Med Chem · research support, non-u.s. gov't; review; journal article · DOI 10.1021/acs.jmedchem.0c00606Fight against novel coronavirus: A perspective of medicinal chemists.
Amin SA, Jha T.
Eur J Med Chem · review-article; review; journal article · DOI 10.1016/j.ejmech.2020.112559A perspective review on fatty acid amide hydrolase (FAAH) inhibitors as potential therapeutic agents.
Tripathi RKP.
Eur J Med Chem · review; journal article · DOI 10.1016/j.ejmech.2019.111953Pharmacophore Identification and Scaffold Exploration to Discover Novel, Potent, and Chemically Stable Inhibitors of Acid Ceramidase in Melanoma Cells.
Ortega JA, Arencibia JM, La Sala G, Borgogno M, Bauer I, Bono L, Braccia C, Armirotti A, Girotto S, Ganesan A, De Vivo M.
J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jmedchem.7b00472Discovery of a new class of highly potent inhibitors of acid ceramidase: synthesis and structure-activity relationship (SAR).
Pizzirani D, Pagliuca C, Realini N, Branduardi D, Bottegoni G, Mor M, Bertozzi F, Scarpelli R, Piomelli D, Bandiera T.
J Med Chem · journal article · DOI 10.1021/jm301879gStructure-based identification of OATP1B1/3 inhibitors.
De Bruyn T, van Westen GJ, Ijzerman AP, Stieger B, de Witte P, Augustijns PF, Annaert PP.
Mol Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1124/mol.112.084152Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Santana L, González-Díaz H, Quezada E, Uriarte E, Yáñez M, Viña D, Orallo F.
J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm800656v