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Publikationer i urvalet

9 träffar

Bibliografisk träff 2005-07-29

Antiemetic activity of FK1052, a 5-HT3- and 5-HT4-receptor antagonist, in Suncus murinus and ferrets.

Nakayama H, Yamakuni H, Higaki M, Ishikawa H, Imazumi K, Matsuo M, Mutoh S.

J Pharmacol Sci · comparative study; journal article · DOI 10.1254/jphs.fpj05001x

Bibliografisk träff 2001-10-01

Prediction of human hepatic clearance from in vivo animal experiments and in vitro metabolic studies with liver microsomes from animals and humans.

Naritomi Y, Terashita S, Kimura S, Suzuki A, Kagayama A, Sugiyama Y.

Drug Metab Dispos · journal article

Bibliografisk träff 2000-03-01

Probable involvement of the 5-hydroxytryptamine(4) receptor in methotrexate-induced delayed emesis in dogs.

Yamakuni H, Sawai H, Maeda Y, Imazumi K, Sakuma H, Matsuo M, Mutoh S, Seki J.

J Pharmacol Exp Ther · journal article · DOI 10.1016/s0022-3565(24)35382-0

Bibliografisk träff 1996-11-01

Participation of 5-HT3, 5-HT4, and nicotinic receptors in the peristaltic reflex of guinea pig distal colon.

Kadowaki M, Wade PR, Gershon MD.

Am J Physiol · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1152/ajpgi.1996.271.5.g849

Bibliografisk träff 1995-08-01

New 5-HT3 (serotonin-3) receptor antagonists. III. An efficient synthesis of carbon 14-labeled (+)-8,9-dihydro-10-methyl-7-[(5-methyl-1H-imidazol-4- yl)methyl]pyrido[1,2-a]indol-6(7H)-one hydrochloride (FK 1052).

Kato M, Nishino S, Ito K, Takasugi H.

Chem Pharm Bull (Tokyo) · journal article · DOI 10.1248/cpb.43.1346

Bibliografisk träff 1994-12-01

New 5-HT3 (serotonin-3) receptor antagonists. I. Synthesis and structure-activity relationships of pyrido[1,2-a]indoles.

Kato M, Ito K, Nishino S, Yamakuni H, Takasugi H.

Chem Pharm Bull (Tokyo) · journal article · DOI 10.1248/cpb.42.2546

Bibliografisk träff 1994-12-01

New 5-HT3 (serotonin-3) receptor antagonists, II. Synthesis and structure-activity relationships of pyrimido[1,6-a]indoles.

Kato M, Nishino S, Ito K, Yamakuni H, Takasugi H.

Chem Pharm Bull (Tokyo) · journal article · DOI 10.1248/cpb.42.2556

Bibliografisk träff 1993-07-01

Effect of FK1052, a potent 5-hydroxytryptamine3 and 5-hydroxytryptamine4 receptor dual antagonist, on colonic function in vivo.

Kadowaki M, Nagakura Y, Tomoi M, Mori J, Kohsaka M.

J Pharmacol Exp Ther · journal article · DOI 10.1016/s0022-3565(25)38330-8

Bibliografisk träff 1993-05-01

Pharmacological characterization of FK1052, a dihydropyridoindole derivative, as a new serotonin 3 and 4 dual receptor antagonist.

Nagakura Y, Kadowaki M, Tokoro K, Tomoi M, Mori J, Kohsaka M.

J Pharmacol Exp Ther · journal article · DOI 10.1016/s0022-3565(25)38203-0