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Publikationer i urvalet

10 träffar

Bibliografisk träff 2023-07-19

A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.

Sutherland JJ, Yonchev D, Fekete A, Urban L.

Nat Commun · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/s41467-023-40064-9

Bibliografisk träff 2020-11-23

Stabilization Strategies for Linear Minigastrin Analogues: Further Improvements <i>via</i> the Inclusion of Proline into the Peptide Sequence.

Klingler M, Hörmann AA, Rangger C, Desrues L, Castel H, Gandolfo P, von Guggenberg E.

J Med Chem · research support, non-u.s. gov't; research-article; journal article · DOI 10.1021/acs.jmedchem.0c01233

Bibliografisk träff 2016-03-03

DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.

Chen M, Suzuki A, Thakkar S, Yu K, Hu C, Tong W.

Drug Discov Today · review; journal article · DOI 10.1016/j.drudis.2016.02.015

Bibliografisk träff 2010-01-01

Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.

Fourches D, Barnes JC, Day NC, Bradley P, Reed JZ, Tropsha A.

Chem Res Toxicol · research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1021/tx900326k

Bibliografisk träff 2001-04-01

Nonpeptide cholecystokinin-2 receptor agonists.

Kalindjian SB, Dunstone DJ, Low CM, Pether MJ, Roberts SP, Tozer MJ, Watt GF, Shankley NP.

J Med Chem · journal article · DOI 10.1021/jm0010668

Bibliografisk träff 1993-03-01

Cholecystokinin dipeptoid antagonists: design, synthesis, and anxiolytic profile of some novel CCK-A and CCK-B selective and "mixed" CCK-A/CCK-B antagonists.

Boden PR, Higginbottom M, Hill DR, Horwell DC, Hughes J, Rees DC, Roberts E, Singh L, Suman-Chauhan N, Woodruff GN.

J Med Chem · journal article · DOI 10.1021/jm00057a005

Bibliografisk träff 1992-07-01

Rationally designed "dipeptoid" analogues of CCK. Acid mimics of the potent and selective non-peptide CCK-B receptor antagonist CI-988.

Drysdale MJ, Pritchard MC, Horwell DC.

J Med Chem · journal article · DOI 10.1021/jm00092a007

Bibliografisk träff 1992-01-01

Structure-antigastrin activity relationships of new (R)-4-benzamido-5-oxopentanoic acid derivatives.

Makovec F, Peris W, Revel L, Giovanetti R, Mennuni L, Rovati LC.

J Med Chem · journal article · DOI 10.1021/jm00079a003

Bibliografisk träff 1991-01-01

Rationally designed "dipeptoid" analogues of CCK. alpha-Methyltryptophan derivatives as highly selective and orally active gastrin and CCK-B antagonists with potent anxiolytic properties.

Horwell DC, Hughes J, Hunter JC, Pritchard MC, Richardson RS, Roberts E, Woodruff GN.

J Med Chem · comparative study; journal article · DOI 10.1021/jm00105a062

Bibliografisk träff 1987-04-01

Synthesis and binding affinities of analogues of cholecystokinin-(30-33) as probes for central nervous system cholecystokinin receptors.

Horwell DC, Beeby A, Clark CR, Hughes J.

J Med Chem · comparative study; journal article · DOI 10.1021/jm00387a027