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Publikationer i urvalet

21 träffar

Bibliografisk träff 2023-07-19

A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.

Sutherland JJ, Yonchev D, Fekete A, Urban L.

Nat Commun · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/s41467-023-40064-9

Bibliografisk träff 2021-04-30

A new sulfated triterpene glycoside from the sea cucumber Colochirus quadrangularis, and evaluation of its antifungal, antitumor and immunomodulatory activities.

Yang WS, Qi XR, Xu QZ, Yuan CH, Yi YH, Tang HF, Shen L, Han H.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2021.116188

Bibliografisk träff 2020-07-16

Fluoropyrimidin-2,4-dihydroxy-5-isopropylbenzamides as antitumor agents against CRC and NSCLC cancer cells.

Wu WC, Liu YM, Liao YH, Hsu KC, Lien ST, Chen IC, Lai MJ, Li YH, Pan SL, Chen MC, Liou JP.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2020.112540

Bibliografisk träff 2010-01-01

Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.

Fourches D, Barnes JC, Day NC, Bradley P, Reed JZ, Tropsha A.

Chem Res Toxicol · research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1021/tx900326k

Bibliografisk träff 2008-10-04

Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.

Santana L, González-Díaz H, Quezada E, Uriarte E, Yáñez M, Viña D, Orallo F.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm800656v

Bibliografisk träff 2007-12-29

Novel prodrugs of tegafur that display improved anticancer activity and antiangiogenic properties.

Engel D, Nudelman A, Tarasenko N, Levovich I, Makarovsky I, Sochotnikov S, Tarasenko I, Rephaeli A.

J Med Chem · journal article · DOI 10.1021/jm7009827

Bibliografisk träff 2007-04-24

Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.

Abraham MH, Ibrahim A, Acree WE.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2007.04.002

Bibliografisk träff 2007-01-04

Synthesis and cytotoxicity of novel fatty acid-nucleoside conjugates.

Zhang YX, Dai GF, Wang L, Tao JC.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2006.12.092

Bibliografisk träff 2004-08-01

[Drug-induced liver injury; fourteenth updated edition of the bibliographic database of liver injuries and related drugs].

Biour M, Ben Salem C, Chazouillères O, Grangé JD, Serfaty L, Poupon R.

Gastroenterol Clin Biol · bibliography; journal article · DOI 10.1016/s0399-8320(04)95062-2

Bibliografisk träff 1996-06-01

Thermodynamic aspects of hydrophobicity and the blood-brain barrier permeability studied with a gel filtration chromatography.

Kai J, Nakamura K, Masuda T, Ueda I, Fujiwara H.

J Med Chem · journal article · DOI 10.1021/jm960068i

Bibliografisk träff 1987-12-01

N-substituted oxopyrimidines and nucleosides: structure-activity relationship for hypnotic activity as central nervous system depressant.

Yamamoto I, Kimura T, Tateoka Y, Watanabe K, Ho IK.

J Med Chem · journal article · DOI 10.1021/jm00395a009

Bibliografisk träff 1986-01-01

(o- and p-Nitrobenzyloxycarbonyl)-5-fluorouracil derivatives as potential conjugated bioreductive alkylating agents.

Lin TS, Wang L, Antonini I, Cosby LA, Shiba DA, Kirkpatrick DL, Sartorelli AC.

J Med Chem · comparative study; research support, non-u.s. gov't; journal article · DOI 10.1021/jm00151a014

Bibliografisk träff 1985-02-01

Synthesis and antitumor activity of a series of ftorafur analogues: the effect of varying electronegativity at the 1'-position.

Holshouser MH, Shipp AM, Ferguson PW.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm00380a016

Bibliografisk träff 1982-10-01

Studies on the synthesis of chemotherapeutics. 12. Synthesis and antitumor activity of N-phthalidyl-5-fluorouracil derivatives.

Kametani T, Kigasawa K, Hiiragi M, Wakisaka K, Nakazato K, Ichikawa K, Fukawa K, Irino O, Nishimura N, Okada T.

J Med Chem · journal article · DOI 10.1021/jm00352a024

Bibliografisk träff 1982-05-01

Synthesis and biological evaluation of novel pyrimidine nucleoside analogues of 1,4-oxathiane, 1,4-dithiane, and 1,4-dioxane.

Hronowski LJ, Szarek WA.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm00347a008

Bibliografisk träff 1980-12-01

Studies on the synthesis of chemotherapeutics. 10. Synthesis and antitumor activity of N-acyl- and N-(alkoxycarbonyl)-5-fluorouracil derivatives.

Kametani T, Kigasawa K, Hiiragi M, Wakisaka K, Haga S, Nagamatsu Y, Sugi H, Fukawa K, Irino O, Yamamoto T, Nishimura N, Taguchi A, Okada T, Nakayama M.

J Med Chem · journal article · DOI 10.1021/jm00186a008

Bibliografisk träff 1980-08-01

Fluorinated pyrimidine nucleosides. 4. Synthesis and antitumor testing of a series of 2',5'-dideoxy- and 2',3',5'-trideoxynucleosides of 5-fluorouracil.

Cook AF, Holman MJ, Kramer MJ.

J Med Chem · journal article · DOI 10.1021/jm00182a008

Bibliografisk träff 1980-06-01

Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability.

Levin VA.

J Med Chem · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm00180a022

Bibliografisk träff 1979-09-01

Synthesis and biological activities of ftorafur metabolites. 3'- and 4'-hydroxyftorafur.

Lin AJ, Benjamin RS, Rao PN, Loo TL.

J Med Chem · journal article · DOI 10.1021/jm00195a017

Bibliografisk träff 1978-08-01

Studies on antitumor agents, 2. Syntheses and antitumor activities of 1-(tetrahydro-2-furanyl)-5-fluorouracil and 1,3-bis(tetrahydro-2-furanyl)-5-fluorouracil.

Yasumoto M, Yamawaki I, Marunaka T, Hashimoto S.

J Med Chem · journal article · DOI 10.1021/jm00206a004

Bibliografisk träff 1977-12-01

Studies of antitumor agents. 1. Resolution of racemic 1-(tetrahydro-2-furanyl)-k-fluorouracil into the R and S isomers and examination of the biological activities of the isomers.

Yasumoto M, Moriyama A, Unemi N, Hashimoto S, Suzue T.

J Med Chem · journal article · DOI 10.1021/jm00222a011