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Publikationer i urvalet

15 träffar

Bibliografisk träff 2023-07-19

A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.

Sutherland JJ, Yonchev D, Fekete A, Urban L.

Nat Commun · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/s41467-023-40064-9

Bibliografisk träff 2022-04-06

Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators.

Zattoni IF, Delabio LC, Dutra JP, Kita DH, Scheiffer G, Hembecker M, Pereira GDS, Moure VR, Valdameri G.

Eur J Med Chem · review; journal article · DOI 10.1016/j.ejmech.2022.114346

Bibliografisk träff 2020-10-24

Development of novel benzimidazole-derived neddylation inhibitors for suppressing tumor growth invitro and invivo.

Chen X, Yang X, Mao F, Wei J, Xu Y, Li B, Zhu J, Ni S, Jia L, Li J.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2020.112964

Bibliografisk träff 2020-03-26

Identification and development of non-cytotoxic cell death modulators: Impact of sartans and derivatives on PPARγ activation and on growth of imatinib-resistant chronic myelogenous leukemia cells.

Schoepf AM, Salcher S, Obexer P, Gust R.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2020.112258

Bibliografisk träff 2019-11-04

Discovery of candesartan cilexetic as a novel neddylation inhibitor for suppressing tumor growth.

Ni S, Chen X, Yu Q, Xu Y, Hu Z, Zhang J, Zhang W, Li B, Yang X, Mao F, Huang J, Sun Y, Li J, Jia L.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2019.111848

Bibliografisk träff 2016-07-19

Targeting the Translesion Synthesis Pathway for the Development of Anti-Cancer Chemotherapeutics.

Korzhnev DM, Hadden MK.

J Med Chem · review; journal article · DOI 10.1021/acs.jmedchem.6b00596

Bibliografisk träff 2013-04-09

Structure-based identification of OATP1B1/3 inhibitors.

De Bruyn T, van Westen GJ, Ijzerman AP, Stieger B, de Witte P, Augustijns PF, Annaert PP.

Mol Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1124/mol.112.084152

Bibliografisk träff 2013-03-29

Inhibitors for the hepatitis C virus RNA polymerase explored by SAR with advanced machine learning methods.

Weidlich IE, Filippov IV, Brown J, Kaushik-Basu N, Krishnan R, Nicklaus MC, Thorpe IF.

Bioorg Med Chem · research support, n.i.h., intramural; research support, non-u.s. gov't; research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1016/j.bmc.2013.03.032

Bibliografisk träff 2010-11-09

Angiotensin II receptor type 1 (AT1) selective nonpeptidic antagonists--a perspective.

Naik P, Murumkar P, Giridhar R, Yadav MR.

Bioorg Med Chem · review; journal article · DOI 10.1016/j.bmc.2010.10.043

Bibliografisk träff 2010-05-01

Colloid formation by drugs in simulated intestinal fluid.

Doak AK, Wille H, Prusiner SB, Shoichet BK.

J Med Chem · research support, american recovery and reinvestment act; research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/jm100254w

Bibliografisk träff 2010-01-01

Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.

Fourches D, Barnes JC, Day NC, Bradley P, Reed JZ, Tropsha A.

Chem Res Toxicol · research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1021/tx900326k

Bibliografisk träff 2003-06-01

Angiotensin II AT1 receptor antagonists. Clinical implications of active metabolites.

Schmidt B, Schieffer B.

J Med Chem · research support, non-u.s. gov't; review; journal article · DOI 10.1021/jm0204237

Bibliografisk träff 2002-02-01

Interaction of digoxin with antihypertensive drugs via MDR1.

Takara K, Kakumoto M, Tanigawara Y, Funakoshi J, Sakaeda T, Okumura K.

Life Sci · journal article · DOI 10.1016/s0024-3205(01)01494-1

Bibliografisk träff 1996-02-01

Nonpeptide angiotensin II receptor antagonists: the next generation in antihypertensive therapy.

Wexler RR, Greenlee WJ, Irvin JD, Goldberg MR, Prendergast K, Smith RD, Timmermans PB.

J Med Chem · review; journal article · DOI 10.1021/jm9504722

Bibliografisk träff 1993-08-01

Nonpeptide angiotensin II receptor antagonists. Synthesis and biological activity of potential prodrugs of benzimidazole-7-carboxylic acids.

Kubo K, Kohara Y, Yoshimura Y, Inada Y, Shibouta Y, Furukawa Y, Kato T, Nishikawa K, Naka T.

J Med Chem · journal article · DOI 10.1021/jm00068a011