Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Rana P, Will Y, Nadanaciva S, Jones LH.
Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2016.06.088 PUBLIKATIONSREGISTRET
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8 träffarDILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Chen M, Suzuki A, Thakkar S, Yu K, Hu C, Tong W.
Drug Discov Today · review; journal article · DOI 10.1016/j.drudis.2016.02.015Attenuating Staphylococcus aureus virulence gene regulation: a medicinal chemistry perspective.
Gordon CP, Williams P, Chan WC.
J Med Chem · research support, non-u.s. gov't; review-article; journal article · DOI 10.1021/jm3014635Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Liu Z, Shi Q, Ding D, Kelly R, Fang H, Tong W.
PLoS Comput Biol · research support, u.s. gov't, p.h.s.; research-article; journal article · DOI 10.1371/journal.pcbi.1002310FDA-approved drug labeling for the study of drug-induced liver injury.
Chen M, Vijay V, Shi Q, Liu Z, Fang H, Tong W.
Drug Discov Today · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1016/j.drudis.2011.05.007Developing potent human uric acid transporter 1 (hURAT1) inhibitors.
Wempe MF, Jutabha P, Quade B, Iwen TJ, Frick MM, Ross IR, Rice PJ, Anzai N, Endou H.
J Med Chem · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/jm1015022Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Fourches D, Barnes JC, Day NC, Bradley P, Reed JZ, Tropsha A.
Chem Res Toxicol · research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1021/tx900326k[Drug-induced liver injury; fourteenth updated edition of the bibliographic database of liver injuries and related drugs].
Biour M, Ben Salem C, Chazouillères O, Grangé JD, Serfaty L, Poupon R.
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