Non-canonical amino acids uncover the significant impact of Tyr671 on Taq DNA polymerase catalytic activity.
Chen W, Chen B, Li X, Xu G, Yang L, Wu J, Yu H.
FEBS J · journal article · DOI 10.1111/febs.17091 PUBLIKATIONSREGISTRET
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Publikationer i urvalet
16 träffarUnnatural activities and mechanistic insights of cytochrome P450 PikC gained from site-specific mutagenesis by non-canonical amino acids.
Pan Y, Li G, Liu R, Guo J, Liu Y, Liu M, Zhang X, Chi L, Xu K, Wu R, Zhang Y, Li Y, Gao X, Li S.
Nat Commun · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/s41467-023-37288-0A linear DNA template-based framework for site-specific unnatural amino acid incorporation.
Chen X, Liu Y, Hou J, Lu Y.
Synth Syst Biotechnol · research-article; journal article · DOI 10.1016/j.synbio.2021.07.003<i>In vitro</i>-Constructed Ribosomes Enable Multi-site Incorporation of Noncanonical Amino Acids into Proteins.
Liu Y, Davis RG, Thomas PM, Kelleher NL, Jewett MC.
Biochemistry · research support, non-u.s. gov't; research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1021/acs.biochem.0c00829Site-specific antibody fragment conjugates for targeted imaging.
Maloney R, Buuh ZY, Zhao Y, Wang RE.
Methods Enzymol · research support, non-u.s. gov't; research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1016/bs.mie.2020.02.023A Highly Productive, One-Pot Cell-Free Protein Synthesis Platform Based on Genomically Recoded Escherichia coli.
Des Soye BJ, Gerbasi VR, Thomas PM, Kelleher NL, Jewett MC.
Cell Chem Biol · research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1016/j.chembiol.2019.10.008Programmable Protein-DNA Cross-Linking for the Direct Capture and Quantification of 5-Formylcytosine.
Gieß M, Muñoz-López Á, Buchmuller B, Kubik G, Summerer D.
J Am Chem Soc · research support, non-u.s. gov't; journal article · DOI 10.1021/jacs.9b01432Active Targeting of Cancer Cells by Nanobody Decorated Polypeptide Micelle with Bio-orthogonally Conjugated Drug.
Costa SA, Mozhdehi D, Dzuricky MJ, Isaacs FJ, Brustad EM, Chilkoti A.
Nano Lett · research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/acs.nanolett.8b03837Metabolism of an Oxime-Linked Antibody Drug Conjugate, AGS62P1, and Characterization of Its Identified Metabolite.
Snyder JT, Malinao MC, Dugal-Tessier J, Atkinson JE, Anand BS, Okada A, Mendelsohn BA.
Mol Pharm · journal article · DOI 10.1021/acs.molpharmaceut.8b00225Cell-free protein synthesis from genomically recoded bacteria enables multisite incorporation of noncanonical amino acids.
Martin RW, Des Soye BJ, Kwon YC, Kay J, Davis RG, Thomas PM, Majewska NI, Chen CX, Marcum RD, Weiss MG, Stoddart AE, Amiram M, Ranji Charna AK, Patel JR, Isaacs FJ, Kelleher NL, Hong SH, Jewett MC.
Nat Commun · research support, non-u.s. gov't; research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1038/s41467-018-03469-5A Switchable Site-Specific Antibody Conjugate.
Lyu Z, Kang L, Buuh ZY, Jiang D, McGuth JC, Du J, Wissler HL, Cai W, Wang RE.
ACS Chem Biol · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/acschembio.8b00107Bioorthogonal fluorescent labeling of functional G-protein-coupled receptors.
Tian H, Naganathan S, Kazmi MA, Schwartz TW, Sakmar TP, Huber T.
Chembiochem · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1002/cbic.201402193Ketoxime coupling of p-acetylphenylalanine at neutral pH for site-directed spin labeling of human sulfite oxidase.
Hahn A, Reschke S, Leimkühler S, Risse T.
J Phys Chem B · research support, non-u.s. gov't; journal article · DOI 10.1021/jp503471jBispecific small molecule-antibody conjugate targeting prostate cancer.
Kim CH, Axup JY, Lawson BR, Yun H, Tardif V, Choi SH, Zhou Q, Dubrovska A, Biroc SL, Marsden R, Pinstaff J, Smider VV, Schultz PG.
Proc Natl Acad Sci U S A · research-article; journal article; research support, n.i.h., extramural · DOI 10.1073/pnas.1316026110Synthesis of site-specific antibody-drug conjugates using unnatural amino acids.
Axup JY, Bajjuri KM, Ritland M, Hutchins BM, Kim CH, Kazane SA, Halder R, Forsyth JS, Santidrian AF, Stafin K, Lu Y, Tran H, Seller AJ, Biroc SL, Szydlik A, Pinkstaff JK, Tian F, Sinha SC, Felding-Habermann B, Smider VV, Schultz PG.
Proc Natl Acad Sci U S A · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1073/pnas.1211023109Rational design of aminoacyl-tRNA synthetase specific for p-acetyl-L-phenylalanine.
Sun R, Zheng H, Fang Z, Yao W.
Biochem Biophys Res Commun · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bbrc.2009.11.125