Topical delivery of anthramycin I. Influence of neat solvents.
Haque T, Rahman KM, Thurston DE, Hadgraft J, Lane ME.
Eur J Pharm Sci · journal article · DOI 10.1016/j.ejps.2017.03.043 PUBLIKATIONSREGISTRET
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Publikationer i urvalet
22 träffarFrom Anthramycin to Pyrrolobenzodiazepine (PBD)-Containing Antibody-Drug Conjugates (ADCs).
Mantaj J, Jackson PJ, Rahman KM, Thurston DE.
Angew Chem Int Ed Engl · review-article; review; journal article · DOI 10.1002/anie.201510610A heme peroxidase with a functional role as an L-tyrosine hydroxylase in the biosynthesis of anthramycin.
Connor KL, Colabroy KL, Gerratana B.
Biochemistry · research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/bi201148aReassembly of anthramycin biosynthetic gene cluster by using recombinogenic cassettes.
Hu Y, Phelan VV, Farnet CM, Zazopoulos E, Bachmann BO.
Chembiochem · research support, non-u.s. gov't; journal article · DOI 10.1002/cbic.200800029Benzodiazepine biosynthesis in Streptomyces refuineus.
Hu Y, Phelan V, Ntai I, Farnet CM, Zazopoulos E, Bachmann BO.
Chem Biol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.chembiol.2007.05.009Anthramycin-DNA binding explored by molecular simulations.
Vargiu AV, Ruggerone P, Magistrato A, Carloni P.
J Phys Chem B · research support, non-u.s. gov't; journal article · DOI 10.1021/jp063155nThe cytotoxicity of anthramycin to mutants of Schizosaccharomyces pombe deficient in DNA damage responses.
Hafiz F, Thurston DE, Carr AM, Jones RW.
Biochem Soc Trans · comparative study; research support, non-u.s. gov't; journal article · DOI 10.1042/bst023331sCrystal structure of a covalent DNA-drug adduct: anthramycin bound to C-C-A-A-C-G-T-T-G-G and a molecular explanation of specificity.
Kopka ML, Goodsell DS, Baikalov I, Grzeskowiak K, Cascio D, Dickerson RE.
Biochemistry · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1021/bi00250a011Correlation of DNA sequence specificity of anthramycin and tomaymycin with reaction kinetics and bending of DNA.
Kizu R, Draves PH, Hurley LH.
Biochemistry · comparative study; research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1021/bi00084a043Comparison of sequence preference of tomaymycin- and anthramycin-DNA bonding by exonuclease III and lambda exonuclease digestion and UvrABC nuclease incision analysis.
Pierce JR, Nazimiec M, Tang MS.
Biochemistry · comparative study; research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1021/bi00079a002Lesion selectivity in blockage of lambda exonuclease by DNA damage.
Mattes WB.
Nucleic Acids Res · research support, non-u.s. gov't; research-article; journal article · DOI 10.1093/nar/18.13.3723All atom molecular mechanics simulations on covalent complexes of anthramycin and neothramycin with deoxydecanucleotides.
Rao SN, Remers WA.
J Med Chem · journal article · DOI 10.1021/jm00168a026Two-dimensional NMR studies on the anthramycin-d(ATGCAT)2 adduct.
Krugh TR, Graves DE, Stone MP.
Biochemistry · research support, u.s. gov't, p.h.s.; research support, u.s. gov't, non-p.h.s.; journal article · DOI 10.1021/bi00452a017Cholecystokinin antagonism by anthramycin, a benzodiazepine antibiotic, in the central nervous system in mice.
Kubota K, Sugaya K, Koizumi Y, Toda M.
Brain Res · research support, non-u.s. gov't; journal article · DOI 10.1016/0006-8993(89)90666-5Recognition of the DNA helix stabilizing anthramycin-N2 guanine adduct by UVRABC nuclease.
Walter RB, Pierce J, Case R, Tang MS.
J Mol Biol · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1016/0022-2836(88)90119-2Bicyclic and tricyclic analogues of anthramycin.
Kaneko T, Wong H, Doyle TW, Rose WC, Bradner WT.
J Med Chem · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm00381a020The reaction of anthramycin with DNA. Proton and carbon nuclear magnetic resonance studies on the structure of the anthramycin-DNA adduct.
Graves DE, Pattaroni C, Krishnan BS, Ostrander JM, Hurley LH, Krugh TR.
J Biol Chem · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1016/s0021-9258(17)39714-4Protection against anthramycin-induced toxicity in mice by coenzyme Q10.
Lubawy WC, Dallam RA, Hurley LH.
J Natl Cancer Inst · research support, u.s. gov't, p.h.s.; journal articlePyrrolo[1,4]benzodiazepine antibiotics. Biosynthetic conversion of tyrosine to the C2- and C3-proline moieties of anthramycin, tomaymycin, and sibiromycin.
Hurley LH, Lasswell WL, Ostrander JM, Parry R.
Biochemistry · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/bi00586a030Mutagenic and recombinogenic effects of the antitumor antibiotic anthramycin.
Hannan MA, Hurley LH, Gairola C.
Cancer Res · research support, u.s. gov't, p.h.s.; journal articlePyrrolo(1,4)benzodiazepine antitumor antibiotics. In vitro interaction of anthramycin, sibiromycin and tomaymycin with DNA using specifically radiolabelled molecules.
Hurley LH, Gairola C, Zmijewski M.
Biochim Biophys Acta · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1016/0005-2787(77)90067-3Anthramycin, a new type of DNA-inhibiting antibiotic: reaction with DNA and effect on nucleic acid synthesis in mouse leukemia cells.
Kohn KW, Bono VH, Kann HE.
Biochim Biophys Acta · journal article · DOI 10.1016/0005-2787(68)90342-0