Trichostatin A mitigates radiation-induced teratogenesis in C57Bl/6 mice.
Haritwal T, Goyal N, Gupta N, Parvez S, Agrawala PK.
Mutagenesis · research support, non-u.s. gov't; journal article · DOI 10.1093/mutage/geab018 PUBLIKATIONSREGISTRET
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Publikationer i urvalet
13 träffarDifferential effects of trichostatin A on mouse embryogenesis and development.
Peng C, Lv Z, Hai T, Dai X, Zhou Q.
Reproduction · research support, non-u.s. gov't; journal article · DOI 10.1530/rep-21-0020Binding of inhibitors to active-site mutants of CD1, the enigmatic catalytic domain of histone deacetylase 6.
Osko JD, Christianson DW.
Acta Crystallogr F Struct Biol Commun · research-article; journal article · DOI 10.1107/s2053230x20010250Structural Basis of Catalysis and Inhibition of HDAC6 CD1, the Enigmatic Catalytic Domain of Histone Deacetylase 6.
Osko JD, Christianson DW.
Biochemistry · research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1021/acs.biochem.9b00934Structural Basis of Sirtuin 6 Inhibition by the Hydroxamate Trichostatin A: Implications for Protein Deacylase Drug Development.
You W, Steegborn C.
J Med Chem · journal article · DOI 10.1021/acs.jmedchem.8b01455Structural insights into HDAC6 tubulin deacetylation and its selective inhibition.
Miyake Y, Keusch JJ, Wang L, Saito M, Hess D, Wang X, Melancon BJ, Helquist P, Gut H, Matthias P.
Nat Chem Biol · research support, non-u.s. gov't; journal article; research support, n.i.h., extramural · DOI 10.1038/nchembio.2140Compromised structure and function of HDAC8 mutants identified in Cornelia de Lange Syndrome spectrum disorders.
Decroos C, Bowman CM, Moser JA, Christianson KE, Deardorff MA, Christianson DW.
ACS Chem Biol · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/cb5003762Microbial transformation of trichostatin A to 2,3-dihydrotrichostatin A.
Park JW, Park SR, Han AR, Ban YH, Yoo YJ, Kim EJ, Kim E, Yoon YJ.
J Nat Prod · research support, non-u.s. gov't; journal article · DOI 10.1021/np1006718An HDAC inhibitor, trichostatin A, induces a delay at G2/M transition, slippage of spindle checkpoint, and cell death in a transcription-dependent manner.
Noh EJ, Lim DS, Jeong G, Lee JS.
Biochem Biophys Res Commun · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bbrc.2008.11.057Human HDAC7 harbors a class IIa histone deacetylase-specific zinc binding motif and cryptic deacetylase activity.
Schuetz A, Min J, Allali-Hassani A, Schapira M, Shuen M, Loppnau P, Mazitschek R, Kwiatkowski NP, Lewis TA, Maglathin RL, McLean TH, Bochkarev A, Plotnikov AN, Vedadi M, Arrowsmith CH.
J Biol Chem · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1074/jbc.m707362200Induction of apoptosis by trichostatin A, a histone deacetylase inhibitor, is associated with inhibition of cyclooxygenase-2 activity in human non-small cell lung cancer cells.
Choi YH.
Int J Oncol · comparative study; research support, non-u.s. gov't; journal article · DOI 10.3892/ijo.27.2.473Trichostatin A extends the lifespan of Drosophila melanogaster by elevating hsp22 expression.
Tao D, Lu J, Sun H, Zhao YM, Yuan ZG, Li XX, Huang BQ.
Acta Biochim Biophys Sin (Shanghai) · research support, non-u.s. gov't; journal article · DOI 10.1093/abbs/36.9.618Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors.
Finnin MS, Donigian JR, Cohen A, Richon VM, Rifkind RA, Marks PA, Breslow R, Pavletich NP.
Nature · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1038/43710