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Publikationer i urvalet

18 träffar

Bibliografisk träff 2014-07-28

Diastereoselective synthesis of fused lactone-pyrrolidinones; application to a formal synthesis of (-)-salinosporamide A.

Logan AW, Sprague SJ, Foster RW, Marx LB, Garzya V, Hallside MS, Thompson AL, Burton JW.

Org Lett · research support, non-u.s. gov't; journal article · DOI 10.1021/ol501662t

Bibliografisk träff 2014-04-15

Antileukemic activity and mechanism of drug resistance to the marine Salinispora tropica proteasome inhibitor salinosporamide A (Marizomib).

Niewerth D, Jansen G, Riethoff LF, van Meerloo J, Kale AJ, Moore BS, Assaraf YG, Anderl JL, Zweegman S, Kaspers GJ, Cloos J.

Mol Pharmacol · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1124/mol.114.092114

Bibliografisk träff 2012-04-01

Inactivation of conserved C. elegans genes engages pathogen- and xenobiotic-associated defenses.

Melo JA, Ruvkun G.

Cell · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.cell.2012.02.050

Bibliografisk träff 2011-12-01

Synthesis of salinosporamide A and its analogs as 20S proteasome inhibitors and SAR summarization.

Ma Y, Qu L, Liu Z, Zhang L, Yang Z, Zhang L.

Curr Top Med Chem · research support, non-u.s. gov't; review; journal article · DOI 10.2174/156802611798281302

Bibliografisk träff 2011-12-01

Selective overproduction of the proteasome inhibitor salinosporamide A via precursor pathway regulation.

Lechner A, Eustáquio AS, Gulder TA, Hafner M, Moore BS.

Chem Biol · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.chembiol.2011.10.014

Bibliografisk träff 2011-05-17

Total synthesis of (-)-salinosporamide A.

Satoh N, Yokoshima S, Fukuyama T.

Org Lett · research support, non-u.s. gov't; journal article · DOI 10.1021/ol200886j

Bibliografisk träff 2011-03-01

Marizomib, a proteasome inhibitor for all seasons: preclinical profile and a framework for clinical trials.

Potts BC, Albitar MX, Anderson KC, Baritaki S, Berkers C, Bonavida B, Chandra J, Chauhan D, Cusack JC, Fenical W, Ghobrial IM, Groll M, Jensen PR, Lam KS, Lloyd GK, McBride W, McConkey DJ, Miller CP, Neuteboom ST, Oki Y, Ovaa H, Pajonk F, Richardson PG, Roccaro AM, Sloss CM, Spear MA, Valashi E, Younes A, Palladino MA.

Curr Cancer Drug Targets · research-article; review; journal article; research support, n.i.h., extramural · DOI 10.2174/156800911794519716

Bibliografisk träff 2011-02-08

Proteasome regulator marizomib (NPI-0052) exhibits prolonged inhibition, attenuated efflux, and greater cytotoxicity than its reversible analogs.

Obaidat A, Weiss J, Wahlgren B, Manam RR, Macherla VR, McArthur K, Chao TH, Palladino MA, Lloyd GK, Potts BC, Enna SJ, Neuteboom ST, Hagenbuch B.

J Pharmacol Exp Ther · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1124/jpet.110.177824

Bibliografisk träff 2011-01-01

Total synthesis of (-)-salinosporamide A.

Kaiya Y, Hasegawa J, Momose T, Sato T, Chida N.

Chem Asian J · research support, non-u.s. gov't; journal article · DOI 10.1002/asia.201000602

Bibliografisk träff 2010-03-25

Generating a generation of proteasome inhibitors: from microbial fermentation to total synthesis of salinosporamide a (marizomib) and other salinosporamides.

Potts BC, Lam KS.

Mar Drugs · review-article; review; journal article · DOI 10.3390/md8040835

Bibliografisk träff 2009-02-01

Antiprotealide is a natural product.

Manam RR, Macherla VR, Tsueng G, Dring CW, Weiss J, Neuteboom ST, Lam KS, Potts BC.

J Nat Prod · journal article · DOI 10.1021/np800578e

Bibliografisk träff 2008-11-05

Discovery and development of the anticancer agent salinosporamide A (NPI-0052).

Fenical W, Jensen PR, Palladino MA, Lam KS, Lloyd GK, Potts BC.

Bioorg Med Chem · research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.bmc.2008.10.075

Bibliografisk träff 2008-10-22

Leaving groups prolong the duration of 20S proteasome inhibition and enhance the potency of salinosporamides.

Manam RR, McArthur KA, Chao TH, Weiss J, Ali JA, Palombella VJ, Groll M, Lloyd GK, Palladino MA, Neuteboom ST, Macherla VR, Potts BC.

J Med Chem · journal article · DOI 10.1021/jm800548b

Bibliografisk träff 2007-07-03

Salinosporamide A (NPI-0052) potentiates apoptosis, suppresses osteoclastogenesis, and inhibits invasion through down-modulation of NF-kappaB regulated gene products.

Ahn KS, Sethi G, Chao TH, Neuteboom ST, Chaturvedi MM, Palladino MA, Younes A, Aggarwal BB.

Blood · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1182/blood-2007-04-084996

Bibliografisk träff 2007-05-12

Enantioselective total synthesis of (-)-Salinosporamide A (NPI-0052).

Ling T, Macherla VR, Manam RR, McArthur KA, Potts BC.

Org Lett · journal article · DOI 10.1021/ol0706051

Bibliografisk träff 2006-11-01

NPI-0052 enhances tumoricidal response to conventional cancer therapy in a colon cancer model.

Cusack JC, Liu R, Xia L, Chao TH, Pien C, Niu W, Palombella VJ, Neuteboom ST, Palladino MA.

Clin Cancer Res · comparative study; evaluation study; journal article; research support, n.i.h., extramural · DOI 10.1158/1078-0432.ccr-06-1151

Bibliografisk träff 2005-06-01

Structure-activity relationship studies of salinosporamide A (NPI-0052), a novel marine derived proteasome inhibitor.

Macherla VR, Mitchell SS, Manam RR, Reed KA, Chao TH, Nicholson B, Deyanat-Yazdi G, Mai B, Jensen PR, Fenical WF, Neuteboom ST, Lam KS, Palladino MA, Potts BC.

J Med Chem · journal article · DOI 10.1021/jm048995+

Bibliografisk träff 2003-01-01

Salinosporamide A: a highly cytotoxic proteasome inhibitor from a novel microbial source, a marine bacterium of the new genus salinospora.

Feling RH, Buchanan GO, Mincer TJ, Kauffman CA, Jensen PR, Fenical W.

Angew Chem Int Ed Engl · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1002/anie.200390115