ActiQs / Forskning

PUBLIKATIONSREGISTRET

Gå till forskningen.

Publikationsdata från Europe PMC och PubMed. Följ källhänvisningar från ämnesregistret till originalpublikationerna.

Publikationer som ChEBI hänvisar till för Grepafloxacin. Visa hela publikationsregistret

En publikationsträff är inte en slutsats. Publikationslistan visar bibliografiska uppgifter. Eventuella forskningsutdrag visas separat med originalunderlag. En källhänvisning visar inte i sig effekt, dosering eller säkerhet.

Publikationer i urvalet

35 träffar

Bibliografisk träff 2023-07-19

A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.

Sutherland JJ, Yonchev D, Fekete A, Urban L.

Nat Commun · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/s41467-023-40064-9

Bibliografisk träff 2022-12-21

Current scenario of quinolone hybrids with potential antibacterial activity against ESKAPE pathogens.

Gao J, Hou H, Gao F.

Eur J Med Chem · review; journal article · DOI 10.1016/j.ejmech.2022.115026

Bibliografisk träff 2020-06-04

Synthesis of Novel Ciprofloxacin-Based Hybrid Molecules toward Potent Antimalarial Activity.

Dana S, Valissery P, Kumar S, Gurung SK, Mondal N, Dhar SK, Mukhopadhyay P.

ACS Med Chem Lett · rapid-communication; journal article · DOI 10.1021/acsmedchemlett.0c00196

Bibliografisk träff 2019-06-28

Quinolone antibiotics.

Pham TDM, Ziora ZM, Blaskovich MAT.

Medchemcomm · review-article; review; journal article · DOI 10.1039/c9md00120d

Bibliografisk träff 2018-01-16

Antiplasmodial and antimalarial activities of quinolone derivatives: An overview.

Fan YL, Cheng XW, Wu JB, Liu M, Zhang FZ, Xu Z, Feng LS.

Eur J Med Chem · review; journal article · DOI 10.1016/j.ejmech.2018.01.039

Bibliografisk träff 2014-03-06

Emergence of pyrido quinoxalines as new family of antimalarial agents.

Chandra Shekhar A, Shanthan Rao P, Narsaiah B, Allanki AD, Sijwali PS.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2014.03.010

Bibliografisk träff 2013-05-07

The synergic modeling for the binding of fluoroquinolone antibiotics to the hERG potassium channel.

Ryu S, Imai YN, Oiki S.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2013.04.074

Bibliografisk träff 2011-12-21

Targeting the liver stage of malaria parasites: a yet unmet goal.

Rodrigues T, Prudêncio M, Moreira R, Mota MM, Lopes F.

J Med Chem · research support, non-u.s. gov't; review; journal article · DOI 10.1021/jm201095h

Bibliografisk träff 2011-12-15

Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Liu Z, Shi Q, Ding D, Kelly R, Fang H, Tong W.

PLoS Comput Biol · research support, u.s. gov't, p.h.s.; research-article; journal article · DOI 10.1371/journal.pcbi.1002310

Bibliografisk träff 2010-12-08

Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.

Sinha N, Sen S.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2010.11.042

Bibliografisk träff 2010-09-15

A predictive ligand-based Bayesian model for human drug-induced liver injury.

Ekins S, Williams AJ, Xu JJ.

Drug Metab Dispos · journal article · DOI 10.1124/dmd.110.035113

Bibliografisk träff 2010-07-01

Developing structure-activity relationships for the prediction of hepatotoxicity.

Greene N, Fisk L, Naven RT, Note RR, Patel ML, Pelletier DJ.

Chem Res Toxicol · journal article · DOI 10.1021/tx1000865

Bibliografisk träff 2009-12-01

Enhancement of the antimalarial activity of ciprofloxacin using a double prodrug/bioorganometallic approach.

Dubar F, Anquetin G, Pradines B, Dive D, Khalife J, Biot C.

J Med Chem · journal article · DOI 10.1021/jm901357n

Bibliografisk träff 2009-10-12

Relative contributions of active mediated transport and passive diffusion of fluoroquinolones with various lipophilicities in a Calu-3 lung epithelial cell model.

Brillault J, De Castro WV, Couet W.

Antimicrob Agents Chemother · comparative study; research-article; journal article · DOI 10.1128/aac.00733-09

Bibliografisk träff 2009-10-05

Prevalence and clonal characterization of Streptococcus pyogenes clinical isolates with reduced fluoroquinolone susceptibility in Spain.

Montes M, Tamayo E, Orden B, Larruskain J, Perez-Trallero E.

Antimicrob Agents Chemother · research support, non-u.s. gov't; research-article; journal article · DOI 10.1128/aac.00780-09

Bibliografisk träff 2008-11-28

GRIND-based 3D-QSAR and CoMFA to investigate topics dominated by hydrophobic interactions: the case of hERG K+ channel blockers.

Ermondi G, Visentin S, Caron G.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2008.11.009

Bibliografisk träff 2008-04-16

Support vector machines classification of hERG liabilities based on atom types.

Jia L, Sun H.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2008.04.028

Bibliografisk träff 2007-08-06

Contributions of the combined effects of topoisomerase mutations toward fluoroquinolone resistance in Escherichia coli.

Morgan-Linnell SK, Zechiedrich L.

Antimicrob Agents Chemother · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1128/aac.00647-07

Bibliografisk träff 2006-08-22

Inhibitory effect of carboxylic acid group on hERG binding.

Zhu BY, Jia ZJ, Zhang P, Su T, Huang W, Goldman E, Tumas D, Kadambi V, Eddy P, Sinha U, Scarborough RM, Song Y.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2006.08.039

Bibliografisk träff 2005-06-01

A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.

Tobita M, Nishikawa T, Nagashima R.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2005.03.080

Bibliografisk träff 2005-03-01

A two-state homology model of the hERG K+ channel: application to ligand binding.

Rajamani R, Tounge BA, Li J, Reynolds CH.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2005.01.008

Bibliografisk träff 2004-08-01

[Drug-induced liver injury; fourteenth updated edition of the bibliographic database of liver injuries and related drugs].

Biour M, Ben Salem C, Chazouillères O, Grangé JD, Serfaty L, Poupon R.

Gastroenterol Clin Biol · bibliography; journal article · DOI 10.1016/s0399-8320(04)95062-2

Bibliografisk träff 2004-02-01

Effect of cisplatin-induced acute renal failure on bioavailability and intestinal secretion of quinolone antibacterial drugs in rats.

Yamaguchi H, Yano I, Saito H, Inui K.

Pharm Res · comparative study; research support, non-u.s. gov't; journal article · DOI 10.1023/b:pham.0000016247.44589.f1

Bibliografisk träff 2003-08-01

Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.

Keserü GM.

Bioorg Med Chem Lett · comparative study; journal article · DOI 10.1016/s0960-894x(03)00492-x

Bibliografisk träff 2003-05-01

Understanding the structure-activity relationship of the human ether-a-go-go-related gene cardiac K+ channel. A model for bad behavior.

Pearlstein R, Vaz R, Rampe D.

J Med Chem · review; journal article · DOI 10.1021/jm0205651

Bibliografisk träff 2002-08-01

Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers.

Cavalli A, Poluzzi E, De Ponti F, Recanatini M.

J Med Chem · journal article · DOI 10.1021/jm0208875

Bibliografisk träff 2002-07-01

cDNA cloning, functional characterization, and tissue distribution of an alternatively spliced variant of organic cation transporter hOCT2 predominantly expressed in the human kidney.

Urakami Y, Akazawa M, Saito H, Okuda M, Inui K.

J Am Soc Nephrol · research support, non-u.s. gov't; journal article · DOI 10.1097/01.asn.0000019413.78751.46

Bibliografisk träff 2002-03-01

Possible involvement of P-glycoprotein in the biliary excretion of grepafloxacin.

Zhao YL, Cai SH, Wang L, Kitaichi K, Tatsumi Y, Nadai M, Yoshizumi H, Takagi K, Takagi K, Hasegawa T.

Clin Exp Pharmacol Physiol · research support, non-u.s. gov't; journal article · DOI 10.1046/j.1440-1681.2002.03627.x

Bibliografisk träff 2001-05-01

Active intestinal secretion of new quinolone antimicrobials and the partial contribution of P-glycoprotein.

Naruhashi K, Tamai I, Inoue N, Muraoka H, Sai Y, Suzuki N, Tsuji A.

J Pharm Pharmacol · journal article · DOI 10.1211/0022357011775820

Bibliografisk träff 2000-10-01

Limited distribution of new quinolone antibacterial agents into brain caused by multiple efflux transporters at the blood-brain barrier.

Tamai I, Yamashita J, Kido Y, Ohnari A, Sai Y, Shima Y, Naruhashi K, Koizumi S, Tsuji A.

J Pharmacol Exp Ther · research support, non-u.s. gov't; journal article · DOI 10.1016/s0022-3565(24)38880-9