ActiQs / Forskning

PUBLIKATIONSREGISTRET

Gå till forskningen.

Publikationsdata från Europe PMC och PubMed. Följ källhänvisningar från ämnesregistret till originalpublikationerna.

Publikationer som ChEBI hänvisar till för Iproniazid. Visa hela publikationsregistret

En publikationsträff är inte en slutsats. Publikationslistan visar bibliografiska uppgifter. Eventuella forskningsutdrag visas separat med originalunderlag. En källhänvisning visar inte i sig effekt, dosering eller säkerhet.

Publikationer i urvalet

50 träffar

Bibliografisk träff 2015-03-20

Multi-target tacrine-coumarin hybrids: cholinesterase and monoamine oxidase B inhibition properties against Alzheimer's disease.

Xie SS, Wang X, Jiang N, Yu W, Wang KD, Lan JS, Li ZR, Kong LY.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2015.03.040

Bibliografisk träff 2014-05-14

New coumarin derivatives: design, synthesis and use as inhibitors of hMAO.

He X, Chen YY, Shi JB, Tang WJ, Pan ZX, Dong ZQ, Song BA, Li J, Liu XH.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2014.05.002

Bibliografisk träff 2014-04-29

Design, synthesis and biological evaluation of novel isoniazid derivatives with potent antitubercular activity.

Martins F, Santos S, Ventura C, Elvas-Leitão R, Santos L, Vitorino S, Reis M, Miranda V, Correia HF, Aires-de-Sousa J, Kovalishyn V, Latino DA, Ramos J, Viveiros M.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2014.04.077

Bibliografisk träff 2014-04-23

New 2H-chromene-3-carboxamide derivatives: design, synthesis and use as inhibitors of hMAO.

Pan ZX, He X, Chen YY, Tang WJ, Shi JB, Tang YL, Song BA, Li J, Liu XH.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2014.04.060

Bibliografisk träff 2014-04-05

Identification of the stereochemical requirements in the 4-aryl-2-cycloalkylidenhydrazinylthiazole scaffold for the design of selective human monoamine oxidase B inhibitors.

D'Ascenzio M, Carradori S, Secci D, Mannina L, Sobolev AP, De Monte C, Cirilli R, Yáñez M, Alcaro S, Ortuso F.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2014.03.042

Bibliografisk träff 2013-10-23

Comparison of Multiple Linear Regressions and Neural Networks based QSAR models for the design of new antitubercular compounds.

Ventura C, Latino DA, Martins F.

Eur J Med Chem · comparative study; research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2013.10.029

Bibliografisk träff 2013-08-16

A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.

Morgan RE, van Staden CJ, Chen Y, Kalyanaraman N, Kalanzi J, Dunn RT, Afshari CA, Hamadeh HK.

Toxicol Sci · journal article · DOI 10.1093/toxsci/kft176

Bibliografisk träff 2013-07-23

Design, synthesis, and in vitro hMAO-B inhibitory evaluation of some 1-methyl-3,5-diphenyl-4,5-dihydro-1H-pyrazoles.

Fioravanti R, Desideri N, Biava M, Proietti Monaco L, Grammatica L, Yáñez M.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2013.07.035

Bibliografisk träff 2013-02-16

Novel (coumarin-3-yl)carbamates as selective MAO-B inhibitors: synthesis, in vitro and in vivo assays, theoretical evaluation of ADME properties and docking study.

Matos MJ, Vilar S, Gonzalez-Franco RM, Uriarte E, Santana L, Friedman C, Tatonetti NP, Viña D, Fontenla JA.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2013.02.009

Bibliografisk träff 2012-11-30

Synthesis of new 7-oxycoumarin derivatives as potent and selective monoamine oxidase A inhibitors.

Abdelhafez OM, Amin KM, Ali HI, Abdalla MM, Batran RZ.

J Med Chem · journal article · DOI 10.1021/jm301014y

Bibliografisk träff 2012-11-15

1,5-Diphenylpenta-2,4-dien-1-ones as potent and selective monoamine oxidase-B inhibitors.

Desideri N, Fioravanti R, Proietti Monaco L, Biava M, Yáñez M, Ortuso F, Alcaro S.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2012.11.006

Bibliografisk träff 2012-10-26

Recent advances in the development of selective human MAO-B inhibitors: (hetero)arylidene-(4-substituted-thiazol-2-yl)hydrazines.

Secci D, Bolasco A, Carradori S, D'Ascenzio M, Nescatelli R, Yáñez M.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2012.10.032

Bibliografisk träff 2012-09-19

Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.

Sakatis MZ, Reese MJ, Harrell AW, Taylor MA, Baines IA, Chen L, Bloomer JC, Yang EY, Ellens HM, Ambroso JL, Lovatt CA, Ayrton AD, Clarke SE.

Chem Res Toxicol · journal article · DOI 10.1021/tx300075j

Bibliografisk träff 2012-09-07

Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.

Warner DJ, Chen H, Cantin LD, Kenna JG, Stahl S, Walker CL, Noeske T.

Drug Metab Dispos · journal article · DOI 10.1124/dmd.112.047068

Bibliografisk träff 2011-12-24

Synthesis and biological assessment of novel 2-thiazolylhydrazones and computational analysis of their recognition by monoamine oxidase B.

Distinto S, Yáñez M, Alcaro S, Cardia MC, Gaspari M, Sanna ML, Meleddu R, Ortuso F, Kirchmair J, Markt P, Bolasco A, Wolber G, Secci D, Maccioni E.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2011.12.027

Bibliografisk träff 2011-12-15

Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Liu Z, Shi Q, Ding D, Kelly R, Fang H, Tong W.

PLoS Comput Biol · research support, u.s. gov't, p.h.s.; research-article; journal article · DOI 10.1371/journal.pcbi.1002310

Bibliografisk träff 2011-11-11

Hydroxycoumarins as selective MAO-B inhibitors.

Serra S, Ferino G, Matos MJ, Vázquez-Rodríguez S, Delogu G, Viña D, Cadoni E, Santana L, Uriarte E.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2011.11.020

Bibliografisk träff 2011-10-01

2D MI-DRAGON: a new predictor for protein-ligands interactions and theoretic-experimental studies of US FDA drug-target network, oxoisoaporphine inhibitors for MAO-A and human parasite proteins.

Prado-Prado F, García-Mera X, Escobar M, Sobarzo-Sánchez E, Yañez M, Riera-Fernandez P, González-Díaz H.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2011.09.045

Bibliografisk träff 2011-09-30

In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.

Dawson S, Stahl S, Paul N, Barber J, Kenna JG.

Drug Metab Dispos · comparative study; journal article · DOI 10.1124/dmd.111.040758

Bibliografisk träff 2011-09-29

Synthesis and study of a series of 3-arylcoumarins as potent and selective monoamine oxidase B inhibitors.

Matos MJ, Terán C, Pérez-Castillo Y, Uriarte E, Santana L, Viña D.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm200716y

Bibliografisk träff 2011-07-19

Synthesis and selective human monoamine oxidase inhibition of 3-carbonyl, 3-acyl, and 3-carboxyhydrazido coumarin derivatives.

Secci D, Carradori S, Bolasco A, Chimenti P, Yáñez M, Ortuso F, Alcaro S.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2011.07.017

Bibliografisk träff 2011-07-01

Chromone, a privileged scaffold for the development of monoamine oxidase inhibitors.

Gaspar A, Silva T, Yáñez M, Vina D, Orallo F, Ortuso F, Uriarte E, Alcaro S, Borges F.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm2004267

Bibliografisk träff 2011-05-30

MAO inhibitory activity modulation: 3-Phenylcoumarins versus 3-benzoylcoumarins.

Matos MJ, Vazquez-Rodriguez S, Uriarte E, Santana L, Viña D.

Bioorg Med Chem Lett · comparative study; research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2011.05.074

Bibliografisk träff 2011-05-20

FDA-approved drug labeling for the study of drug-induced liver injury.

Chen M, Vijay V, Shi Q, Liu Z, Fang H, Tong W.

Drug Discov Today · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1016/j.drudis.2011.05.007

Bibliografisk träff 2011-03-15

Homoisoflavonoids: natural scaffolds with potent and selective monoamine oxidase-B inhibition properties.

Desideri N, Bolasco A, Fioravanti R, Monaco LP, Orallo F, Yáñez M, Ortuso F, Alcaro S.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm1013709

Bibliografisk träff 2011-01-28

Synthesis, human monoamine oxidase inhibitory activity and molecular docking studies of 3-heteroarylcoumarin derivatives.

Delogu G, Picciau C, Ferino G, Quezada E, Podda G, Uriarte E, Viña D.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2011.01.033

Bibliografisk träff 2010-12-05

Chromone 3-phenylcarboxamides as potent and selective MAO-B inhibitors.

Gaspar A, Reis J, Fonseca A, Milhazes N, Viña D, Uriarte E, Borges F.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2010.11.128

Bibliografisk träff 2010-09-17

Synthesis and molecular modelling studies of prenylated pyrazolines as MAO-B inhibitors.

Fioravanti R, Bolasco A, Manna F, Rossi F, Orallo F, Yáñez M, Vitali A, Ortuso F, Alcaro S.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2010.09.061

Bibliografisk träff 2010-09-15

A predictive ligand-based Bayesian model for human drug-induced liver injury.

Ekins S, Williams AJ, Xu JJ.

Drug Metab Dispos · journal article · DOI 10.1124/dmd.110.035113

Bibliografisk träff 2010-09-09

Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.

Morgan RE, Trauner M, van Staden CJ, Lee PH, Ramachandran B, Eschenberg M, Afshari CA, Qualls CW, Lightfoot-Dunn R, Hamadeh HK.

Toxicol Sci · journal article · DOI 10.1093/toxsci/kfq269