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Publikationer i urvalet

16 träffar

Bibliografisk träff 2017-02-06

Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells.

Keller AN, Eckle SB, Xu W, Liu L, Hughes VA, Mak JY, Meehan BS, Pediongco T, Birkinshaw RW, Chen Z, Wang H, D'Souza C, Kjer-Nielsen L, Gherardin NA, Godfrey DI, Kostenko L, Corbett AJ, Purcell AW, Fairlie DP, McCluskey J, Rossjohn J.

Nat Immunol · research support, non-u.s. gov't; journal article · DOI 10.1038/ni.3679

Bibliografisk träff 2012-01-01

Increase in covalent binding of 5-hydroxydiclofenac to hepatic tissues in rats co-treated with lipopolysaccharide and diclofenac: involvement in the onset of diclofenac-induced idiosyncratic hepatotoxicity.

Kishida T, Onozato T, Kanazawa T, Tanaka S, Kuroda J.

J Toxicol Sci · journal article · DOI 10.2131/jts.37.1143

Bibliografisk träff 2008-09-01

Oxidation of diclofenac with ozone in aqueous solution.

Sein MM, Zedda M, Tuerk J, Schmidt TC, Golloch A, Von Sonntag C.

Environ Sci Technol · research support, non-u.s. gov't; journal article · DOI 10.1021/es8008612

Bibliografisk träff 2008-06-12

Relationship between CYP2C8 genotypes and diclofenac 5-hydroxylation in healthy Spanish volunteers.

Dorado P, Cavaco I, Cáceres MC, Piedade R, Ribeiro V, Llerena A, Llerena A.

Eur J Clin Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1007/s00228-008-0508-4

Bibliografisk träff 2006-11-10

Investigation of the immunogenicity of diclofenac and diclofenac metabolites.

Naisbitt DJ, Sanderson LS, Meng X, Stachulski AV, Clarke SE, Park BK.

Toxicol Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.toxlet.2006.10.014

Bibliografisk träff 2004-08-01

Diclofenac-induced antibodies against red blood cells are heterogeneous and recognize different epitopes.

Sachs UJ, Santoso S, Röder L, Smart E, Bein G, Kroll H.

Transfusion · research support, non-u.s. gov't; journal article · DOI 10.1111/j.1537-2995.2004.04025.x

Bibliografisk träff 2004-05-01

Syntheses and characterization of the acyl glucuronide and hydroxy metabolites of diclofenac.

Kenny JR, Maggs JL, Meng X, Sinnott D, Clarke SE, Park BK, Stachulski AV.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm030891w

Bibliografisk träff 2003-12-01

Diclofenac induces apoptosis in hepatocytes by alteration of mitochondrial function and generation of ROS.

Gómez-Lechón MJ, Ponsoda X, O'Connor E, Donato T, Castell JV, Jover R.

Biochem Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bcp.2003.08.003

Bibliografisk träff 2003-05-07

CYP2C9 genotypes and diclofenac metabolism in Spanish healthy volunteers.

Dorado P, Berecz R, Norberto MJ, Yasar U, Dahl ML, LLerena A, LLerena A.

Eur J Clin Pharmacol · clinical trial; research support, non-u.s. gov't; journal article · DOI 10.1007/s00228-003-0588-0

Bibliografisk träff 1999-09-01

Hepatic metabolism of diclofenac: role of human CYP in the minor oxidative pathways.

Bort R, Macé K, Boobis A, Gómez-Lechón MJ, Pfeifer A, Castell J.

Biochem Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1016/s0006-2952(99)00167-7

Bibliografisk träff 1999-02-01

Roles of human hepatic cytochrome P450s 2C9 and 3A4 in the metabolic activation of diclofenac.

Tang W, Stearns RA, Wang RW, Chiu SH, Baillie TA.

Chem Res Toxicol · journal article · DOI 10.1021/tx9802217

Bibliografisk träff 1999-02-01

Metabolic activation of diclofenac by human cytochrome P450 3A4: role of 5-hydroxydiclofenac.

Shen S, Marchick MR, Davis MR, Doss GA, Pohl LR.

Chem Res Toxicol · journal article · DOI 10.1021/tx9802365

Bibliografisk träff 1999-01-01

Diclofenac toxicity to hepatocytes: a role for drug metabolism in cell toxicity.

Bort R, Ponsoda X, Jover R, Gómez-Lechón MJ, Castell JV.

J Pharmacol Exp Ther · research support, non-u.s. gov't; journal article · DOI 10.1016/s0022-3565(24)37925-x

Bibliografisk träff 1997-04-01

Oxidation of diclofenac to reactive intermediates by neutrophils, myeloperoxidase, and hypochlorous acid.

Miyamoto G, Zahid N, Uetrecht JP.

Chem Res Toxicol · research support, non-u.s. gov't; journal article · DOI 10.1021/tx960190k

Bibliografisk träff 1995-05-01

Analysis of diclofenac and four of its metabolites in human urine by HPLC.

Sawchuk RJ, Maloney JA, Cartier LL, Rackley RJ, Chan KK, Lau HS.

Pharm Res · journal article · DOI 10.1023/a:1016276012891

Bibliografisk träff 1990-09-01

Synthesis and quantitative structure-activity relationships of diclofenac analogues.

Moser P, Sallmann A, Wiesenberg I.

J Med Chem · journal article · DOI 10.1021/jm00171a008