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Publikationer i urvalet

8 träffar

Bibliografisk träff 2009-12-02

1-tert-butyl-3-[6-(3,5-dimethoxy-phenyl)-2-(4-diethylamino-butylamino)-pyrido[2,3-d]pyrimidin-7-yl]-urea (PD173074), a selective tyrosine kinase inhibitor of fibroblast growth factor receptor-3 (FGFR3), inhibits cell proliferation of bladder cancer carrying the FGFR3 gene mutation along with up-regulation of p27/Kip1 and G1/G0 arrest.

Miyake M, Ishii M, Koyama N, Kawashima K, Kodama T, Anai S, Fujimoto K, Hirao Y, Sugano K.

J Pharmacol Exp Ther · research support, non-u.s. gov't; journal article · DOI 10.1124/jpet.109.162768

Bibliografisk träff 2009-11-10

The fibroblast growth factor receptor inhibitor PD173074 blocks small cell lung cancer growth in vitro and in vivo.

Pardo OE, Latigo J, Jeffery RE, Nye E, Poulsom R, Spencer-Dene B, Lemoine NR, Stamp GW, Aboagye EO, Seckl MJ.

Cancer Res · research support, non-u.s. gov't; journal article · DOI 10.1158/0008-5472.can-09-1576

Bibliografisk träff 2009-04-02

Glioblastoma cell growth is suppressed by disruption of Fibroblast Growth Factor pathway signaling.

Loilome W, Joshi AD, ap Rhys CM, Piccirillo S, Vescovi AL, Gallia GL, Riggins GJ.

J Neurooncol · research support, non-u.s. gov't; journal article; research support, n.i.h., extramural · DOI 10.1007/s11060-009-9885-5

Bibliografisk träff 2007-02-01

Target therapy using a small molecule inhibitor against angiogenic receptors in pancreatic cancer.

Büchler P, Reber HA, Roth MM, Shiroishi M, Friess H, Hines OJ.

Neoplasia · research-article; journal article · DOI 10.1593/neo.06616

Bibliografisk träff 2006-02-01

Differential phosphoprotein mapping in cancer cells using protein microarrays produced from 2-D liquid fractionation.

Pal M, Moffa A, Sreekumar A, Ethier SP, Barder TJ, Chinnaiyan A, Lubman DM.

Anal Chem · research support, non-u.s. gov't; journal article; research support, n.i.h., extramural · DOI 10.1021/ac0511243

Bibliografisk träff 2004-02-11

Cooperation between sonic hedgehog and fibroblast growth factor/MAPK signalling pathways in neocortical precursors.

Kessaris N, Jamen F, Rubin LL, Richardson WD.

Development · research support, non-u.s. gov't; journal article · DOI 10.1242/dev.01027

Bibliografisk träff 2004-01-08

Inhibition of fibroblast growth factor receptor 3 induces differentiation and apoptosis in t(4;14) myeloma.

Trudel S, Ely S, Farooqi Y, Affer M, Robbiani DF, Chesi M, Bergsagel PL.

Blood · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1182/blood-2003-10-3650

Bibliografisk träff 2003-11-01

Specific inhibitor of FGF receptor signaling: FGF-2-mediated effects on proliferation, differentiation, and MAPK activation are inhibited by PD173074 in oligodendrocyte-lineage cells.

Bansal R, Magge S, Winkler S.

J Neurosci Res · comparative study; research support, u.s. gov't, p.h.s.; journal article · DOI 10.1002/jnr.10773