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Publikationer i urvalet

22 träffar

Bibliografisk träff 2021-01-18

Novel sampangine derivatives as potent inhibitors of Cu<sup>2+</sup>-mediated amyloid-β protein aggregation, oxidative stress and inflammation.

Zou XY, Xie RR, Li W, Su CL, Chen YS, Tang H.

Int J Biol Macromol · journal article · DOI 10.1016/j.ijbiomac.2021.01.091

Bibliografisk träff 2020-07-07

Inhibitory potency of 4- substituted sampangine derivatives toward Cu<sup>2+</sup> mediated aggregation of amyloid β-peptide, oxidative stress, and inflammation in Alzheimer's disease.

Su C, Chen Y, Chen K, Li W, Tang H.

Neurochem Int · research support, non-u.s. gov't; journal article · DOI 10.1016/j.neuint.2020.104794

Bibliografisk träff 2019-05-22

Discovery of Simplified Sampangine Derivatives with Potent Antifungal Activities against Cryptococcal Meningitis.

Li Z, Liu N, Tu J, Ji C, Han G, Sheng C.

ACS Infect Dis · research support, non-u.s. gov't; journal article · DOI 10.1021/acsinfecdis.9b00086

Bibliografisk träff 2019-01-25

Discovery of novel simplified isoxazole derivatives of sampangine as potent anti-cryptococcal agents.

Li Z, Liu N, Tu J, Ji C, Han G, Wang Y, Sheng C.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2019.01.029

Bibliografisk träff 2017-10-24

Novel Cell-Killing Mechanisms of Hydroxyurea and the Implication toward Combination Therapy for the Treatment of Fungal Infections.

Singh A, Agarwal A, Xu YJ.

Antimicrob Agents Chemother · research-article; journal article · DOI 10.1128/aac.00734-17

Bibliografisk träff 2017-10-16

Discovery of simplified sampangine derivatives as novel fungal biofilm inhibitors.

Liu N, Zhong H, Tu J, Jiang Z, Jiang Y, Jiang Y, Jiang Y, Li J, Zhang W, Wang Y, Sheng C.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2017.10.043

Bibliografisk träff 2016-01-01

Structure- and Ligand-Based Approaches to Evaluate Aporphynic Alkaloids from Annonaceae as Multi-Target Agent Against Leishmania donovani.

Lorenzo VP, Lúcio AS, Scotti L, Tavares JF, Filho JM, Lima TK, Rocha JD, Scotti MT.

Curr Pharm Des · research support, non-u.s. gov't; review; journal article · DOI 10.2174/1381612822666160513144853

Bibliografisk träff 2015-12-04

Sampangine (a Copyrine Alkaloid) Exerts Biological Activities through Cellular Redox Cycling of Its Quinone and Semiquinone Intermediates.

Mahdi F, Morgan JB, Liu W, Agarwal AK, Jekabsons MB, Liu Y, Zhou YD, Nagle DG.

J Nat Prod · research support, non-u.s. gov't; journal article; research support, n.i.h., extramural · DOI 10.1021/acs.jnatprod.5b00819

Bibliografisk träff 2015-10-01

The discovery of novel antifungal scaffolds by structural simplification of the natural product sampangine.

Jiang Z, Liu N, Hu D, Dong G, Miao Z, Yao J, He H, Jiang Y, Zhang W, Wang Y, Sheng C.

Chem Commun (Camb) · research support, non-u.s. gov't; journal article · DOI 10.1039/c5cc05699c

Bibliografisk träff 2014-08-01

Scaffold hopping of sampangine: discovery of potent antifungal lead compound against Aspergillus fumigatus and Cryptococcus neoformans.

Jiang Z, Liu N, Dong G, Jiang Y, Liu Y, He X, Huang Y, He S, Chen W, Li Z, Yao J, Miao Z, Zhang W, Sheng C.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2014.07.064

Bibliografisk träff 2013-06-18

Synthesis and antimycobacterial activity of analogues of the bioactive natural products sampangine and cleistopholine.

Claes P, Cappoen D, Mbala BM, Jacobs J, Mertens B, Mathys V, Verschaeve L, Huygen K, De Kimpe N.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2013.06.010

Bibliografisk träff 2011-09-09

Sampangine inhibits heme biosynthesis in both yeast and human.

Huang Z, Chen K, Xu T, Zhang J, Li Y, Li W, Agarwal AK, Clark AM, Phillips JD, Pan X.

Eukaryot Cell · research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1128/ec.05170-11

Bibliografisk träff 2011-08-22

Azaphenanthrene alkaloids with antitumoral activity from Anaxagorea dolichocarpa Sprague & Sandwith (Annonaceae).

Lúcio AS, Almeida JR, Barbosa-Filho JM, Pita JC, Branco MV, Diniz Mde F, Agra Mde F, da-Cunha EV, da Silva MS, Tavares JF.

Molecules · research support, non-u.s. gov't; research-article; journal article · DOI 10.3390/molecules16087125

Bibliografisk träff 2011-04-19

Isolation and synthesis of antiproliferative eupolauridine alkaloids of Ambavia gerrardii from the Madagascar Dry Forest.

Pan E, Cao S, Brodie PJ, Callmander MW, Randrianaivo R, Rakotonandrasana S, Rakotobe E, Rasamison VE, TenDyke K, Shen Y, Suh EM, Kingston DG.

J Nat Prod · research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1021/np200093n

Bibliografisk träff 2007-12-21

Role of heme in the antifungal activity of the azaoxoaporphine alkaloid sampangine.

Agarwal AK, Xu T, Jacob MR, Feng Q, Lorenz MC, Walker LA, Clark AM.

Eukaryot Cell · research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1128/ec.00323-07

Bibliografisk träff 2007-08-01

Hetero analogues of the antimicrobial alkaloids cleistopholine and sampangine.

Mink K, Bracher F.

Arch Pharm (Weinheim) · journal article · DOI 10.1002/ardp.200700064

Bibliografisk träff 2005-11-11

Induction of apoptosis by the plant alkaloid sampangine in human HL-60 leukemia cells is mediated by reactive oxygen species.

Kluza J, Mazinghien R, Degardin K, Lansiaux A, Bailly C.

Eur J Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejphar.2005.09.050

Bibliografisk träff 2003-12-01

Apoptosis induced by the alkaloid sampangine in HL-60 leukemia cells: correlation between the effects on the cell cycle progression and changes of mitochondrial potential.

Kluza J, Clark AM, Bailly C.

Ann N Y Acad Sci · journal article · DOI 10.1196/annals.1299.059

Bibliografisk träff 2001-05-01

Antimalarial, cytotoxic, and antifungal alkaloids from Duguetia hadrantha.

Muhammad I, Dunbar DC, Takamatsu S, Walker LA, Clark AM.

J Nat Prod · research support, non-u.s. gov't; research support, u.s. gov't, non-p.h.s.; journal article · DOI 10.1021/np000436s

Bibliografisk träff 2000-05-01

Characterization of the major metabolite of sampangine in rats.

Orabi KY, Walker LA, Clark AM, Hufford CD.

J Nat Prod · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/np990552z

Bibliografisk träff 1999-07-01

Microbial transformation of sampangine.

Orabi KY, Li E, Clark AM, Hufford CD.

J Nat Prod · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/np980457a

Bibliografisk träff 1992-10-01

Copyrine alkaloids: synthesis, spectroscopic characterization, and antimycotic/antimycobacterial activity of A- and B-ring-functionalized sampangines.

Peterson JR, Zjawiony JK, Liu S, Hufford CD, Clark AM, Rogers RD.

J Med Chem · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; research support, u.s. gov't, non-p.h.s.; journal article · DOI 10.1021/jm00100a012