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Publikationer i urvalet

18 träffar

Bibliografisk träff 2021-08-06

An Experimental Toolbox for Structure-Based Hit Discovery for P. aeruginosa FabF, a Promising Target for Antibiotics.

Espeland LO, Georgiou C, Klein R, Bhukya H, Haug BE, Underhaug J, Mainkar PS, Brenk R.

ChemMedChem · research support, non-u.s. gov't; research-article; journal article · DOI 10.1002/cmdc.202100302

Bibliografisk träff 2020-06-10

Platensimycin-Encapsulated Liposomes or Micelles as Biosafe Nanoantibiotics Exhibited Strong Antibacterial Activities against Methicillin-Resistant <i>Staphylococcus aureus</i> Infection in Mice.

Wang Z, Liu X, Peng Y, Su M, Zhu S, Pan J, Shen B, Duan Y, Huang Y.

Mol Pharm · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.molpharmaceut.0c00194

Bibliografisk träff 2019-07-23

Characterization and Crystal Structure of a Nonheme Diiron Monooxygenase Involved in Platensimycin and Platencin Biosynthesis.

Dong LB, Liu YC, Cepeda AJ, Kalkreuter E, Deng MR, Rudolf JD, Chang C, Joachimiak A, Phillips GN, Shen B.

J Am Chem Soc · research support, non-u.s. gov't; research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1021/jacs.9b06183

Bibliografisk träff 2019-07-02

Late-Stage Functionalization of Platensimycin Leading to Multiple Analogues with Improved Antibacterial Activity in Vitro and in Vivo.

Deng Y, Weng X, Li Y, Su M, Wen Z, Ji X, Ren N, Shen B, Duan Y, Huang Y.

J Med Chem · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/acs.jmedchem.9b00616

Bibliografisk träff 2019-04-01

Stereoselective functionalization of platensimycin and platencin by sulfa-Michael/aldol reactions.

Qiu L, Wen Z, Li Y, Tian K, Deng Y, Shen B, Duan Y, Huang Y.

Org Biomol Chem · research support, non-u.s. gov't; journal article · DOI 10.1039/c9ob00324j

Bibliografisk träff 2019-02-19

Cryptic and Stereospecific Hydroxylation, Oxidation, and Reduction in Platensimycin and Platencin Biosynthesis.

Dong LB, Zhang X, Rudolf JD, Deng MR, Kalkreuter E, Cepeda AJ, Renata H, Shen B.

J Am Chem Soc · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/jacs.8b13452

Bibliografisk träff 2018-12-05

Semisynthesis of Platensimycin Derivatives with Antibiotic Activities in Mice via Suzuki-Miyaura Cross-Coupling Reactions.

Deng Y, Su M, Kang D, Liu X, Wen Z, Li Y, Qiu L, Shen B, Duan Y, Huang Y.

J Med Chem · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/acs.jmedchem.8b01580

Bibliografisk träff 2018-11-29

Semisynthesis and Biological Evaluation of Platensimycin Analogues with Varying Aminobenzoic Acids.

Tian K, Deng Y, Qiu L, Zhu X, Shen B, Duan Y, Huang Y.

ChemistrySelect · research-article; journal article · DOI 10.1002/slct.201802475

Bibliografisk träff 2018-09-18

Cytochrome P450-Catalyzed Hydroxylation Initiating Ether Formation in Platensimycin Biosynthesis.

Rudolf JD, Dong LB, Zhang X, Renata H, Shen B.

J Am Chem Soc · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/jacs.8b08012

Bibliografisk träff 2016-10-03

The Fatty Acid Synthase Inhibitor Platensimycin Improves Insulin Resistance without Inducing Liver Steatosis in Mice and Monkeys.

Singh SB, Kang L, Nawrocki AR, Zhou D, Wu M, Previs S, Miller C, Liu H, Hines CD, Madeira M, Cao J, Herath K, Spears LD, Semenkovich, Wang L, Kelley DE, Li C, Guan HP.

PLoS One · research-article; journal article · DOI 10.1371/journal.pone.0164133

Bibliografisk träff 2016-04-28

Titer improvement and pilot-scale production of platensimycin from Streptomyces platensis SB12026.

Shi J, Pan J, Liu L, Yang D, Lu S, Zhu X, Shen B, Duan Y, Huang Y.

J Ind Microbiol Biotechnol · research-article; journal article · DOI 10.1007/s10295-016-1769-z

Bibliografisk träff 2013-02-11

Stereoselective approach to the racemic oxatetracyclic core of platensimycin.

Horii S, Torihata M, Nagasawa T, Kuwahara S.

J Org Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jo302813y

Bibliografisk träff 2011-09-14

Platensimycin and platencin: promising antibiotics for future application in human medicine.

Martens E, Demain AL.

J Antibiot (Tokyo) · review; journal article · DOI 10.1038/ja.2011.80

Bibliografisk träff 2011-08-02

Platensimycin and its relatives: a recent story in the struggle to develop new naturally derived antibiotics.

Saleem M, Hussain H, Hussain H, Ahmed I, van Ree T, Krohn K.

Nat Prod Rep · review; journal article · DOI 10.1039/c1np00010a

Bibliografisk träff 2011-01-07

Platensimycin and platencin congeners from Streptomyces platensis.

Zhang C, Ondeyka J, Herath K, Jayasuriya H, Guan Z, Zink DL, Dietrich L, Burgess B, Ha SN, Wang J, Singh SB.

J Nat Prod · journal article · DOI 10.1021/np100635f

Bibliografisk träff 2010-01-01

Recent advances on platensimycin: a potential antimicrobial agent.

Lu X, You Q.

Curr Med Chem · research support, non-u.s. gov't; review; journal article · DOI 10.2174/092986710790827852

Bibliografisk träff 2009-06-17

Isolation, enzyme-bound structure and antibacterial activity of platencin A1 from Streptomyces platensis.

Singh SB, Ondeyka JG, Herath KB, Zhang C, Jayasuriya H, Zink DL, Parthasarathy G, Becker JW, Wang J, Soisson SM.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2009.06.061

Bibliografisk träff 2006-05-01

Platensimycin is a selective FabF inhibitor with potent antibiotic properties.

Wang J, Soisson SM, Young K, Shoop W, Kodali S, Galgoci A, Painter R, Parthasarathy G, Tang YS, Cummings R, Ha S, Dorso K, Motyl M, Jayasuriya H, Ondeyka J, Herath K, Zhang C, Hernandez L, Allocco J, Basilio A, Tormo JR, Genilloud O, Vicente F, Pelaez F, Colwell L, Lee SH, Michael B, Felcetto T, Gill C, Silver LL, Hermes JD, Bartizal K, Barrett J, Schmatz D, Becker JW, Cully D, Singh SB.

Nature · research support, non-u.s. gov't; journal article · DOI 10.1038/nature04784