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Publikationer som ChEBI hänvisar till för linaclotide. Visa hela publikationsregistret

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Publikationer i urvalet

22 träffar

Bibliografisk träff 2012-11-01

Linaclotide for irritable bowel syndrome with constipation: a 26-week, randomized, double-blind, placebo-controlled trial to evaluate efficacy and safety.

Chey WD, Lembo AJ, Lavins BJ, Shiff SJ, Kurtz CB, Currie MG, MacDougall JE, Jia XD, Shao JZ, Fitch DA, Baird MJ, Schneier HA, Johnston JM.

Am J Gastroenterol · clinical trial, phase iii; research support, non-u.s. gov't; randomized controlled trial; journal article · DOI 10.1038/ajg.2012.254

Bibliografisk träff 2012-11-01

A 12-week, randomized, controlled trial with a 4-week randomized withdrawal period to evaluate the efficacy and safety of linaclotide in irritable bowel syndrome with constipation.

Rao S, Lembo AJ, Shiff SJ, Lavins BJ, Currie MG, Jia XD, Shi K, MacDougall JE, Shao JZ, Eng P, Fox SM, Schneier HA, Kurtz CB, Johnston JM.

Am J Gastroenterol · clinical trial, phase iii; research-article; multicenter study; randomized controlled trial; journal article · DOI 10.1038/ajg.2012.255

Bibliografisk träff 2012-08-24

Pharmacodynamic and clinical endpoints for functional colonic disorders: statistical considerations.

Zinsmeister AR, Burton D, Camilleri M.

Dig Dis Sci · meta-analysis; research-article; journal article · DOI 10.1007/s10620-012-2369-z

Bibliografisk träff 2012-06-25

Linaclotide: evidence for its potential use in irritable bowel syndrome and chronic constipation.

Lee N, Wald A.

Core Evid · review-article; journal article · DOI 10.2147/ce.s25240

Bibliografisk träff 2012-05-03

Contrasting effects of linaclotide and lubiprostone on restitution of epithelial cell barrier properties and cellular homeostasis after exposure to cell stressors.

Cuppoletti J, Blikslager AT, Chakrabarti J, Nighot PK, Malinowska DH.

BMC Pharmacol · research support, non-u.s. gov't; research-article; journal article · DOI 10.1186/1471-2210-12-3

Bibliografisk träff 2012-03-01

Linaclotide in the management of gastrointestinal tract disorders.

Lacy BE, Levenick JM, Crowell MD.

Drugs Today (Barc) · review; journal article · DOI 10.1358/dot.2012.48.3.1745228

Bibliografisk träff 2012-02-01

Clarification of trial end points presented in a recent review of linaclotide.

Johnston JM, Schneier HA.

Expert Rev Gastroenterol Hepatol · letter; comment · DOI 10.1586/egh.11.89

Bibliografisk träff 2011-11-01

Linaclotide: a novel approach to the treatment of irritable bowel syndrome.

Wensel TM, Luthin DR.

Ann Pharmacother · review; journal article · DOI 10.1345/aph.1q428

Bibliografisk träff 2011-10-01

Chronic constipation: current treatment options.

Liu LW.

Can J Gastroenterol · research-article; review; journal article · DOI 10.1155/2011/360463

Bibliografisk träff 2011-10-01

The approach to diagnosis and treatment of chronic constipation: suggestions for a general practitioner.

Pare P.

Can J Gastroenterol · research-article; journal article · DOI 10.1155/2011/368189

Bibliografisk träff 2011-08-01

Two randomized trials of linaclotide for chronic constipation.

Lembo AJ, Schneier HA, Shiff SJ, Kurtz CB, MacDougall JE, Jia XD, Shao JZ, Lavins BJ, Currie MG, Fitch DA, Jeglinski BI, Eng P, Fox SM, Johnston JM.

N Engl J Med · clinical trial, phase iii; research support, non-u.s. gov't; multicenter study; randomized controlled trial; journal article · DOI 10.1056/nejmoa1010863

Bibliografisk träff 2011-06-01

Linaclotide, a synthetic guanylate cyclase C agonist, for the treatment of functional gastrointestinal disorders associated with constipation.

Vazquez Roque M, Camilleri M.

Expert Rev Gastroenterol Hepatol · review; journal article · DOI 10.1586/egh.11.30

Bibliografisk träff 2011-05-01

Diagnosis and treatment of irritable bowel syndrome.

Suares NC, Ford AC.

Discov Med · review; journal article

Bibliografisk träff 2011-03-30

The pharmacokinetics, pharmacodynamics, clinical efficacy, safety and tolerability of linaclotide.

Lee N, Wald A.

Expert Opin Drug Metab Toxicol · review; journal article · DOI 10.1517/17425255.2011.572875

Bibliografisk träff 2011-02-01

Effect of laxatives and pharmacological therapies in chronic idiopathic constipation: systematic review and meta-analysis.

Ford AC, Suares NC.

Gut · meta-analysis; systematic review; journal article · DOI 10.1136/gut.2010.227132

Bibliografisk träff 2011-02-01

Current and future therapies for chronic constipation.

Tack J.

Best Pract Res Clin Gastroenterol · review; journal article · DOI 10.1016/j.bpg.2011.01.005

Bibliografisk träff 2010-12-24

Regulation and therapeutic targeting of peptide-activated receptor guanylyl cyclases.

Potter LR.

Pharmacol Ther · research-article; review; journal article; research support, n.i.h., extramural · DOI 10.1016/j.pharmthera.2010.12.005

Bibliografisk träff 2010-09-20

Linaclotide, through activation of guanylate cyclase C, acts locally in the gastrointestinal tract to elicit enhanced intestinal secretion and transit.

Busby RW, Bryant AP, Bartolini WP, Cordero EA, Hannig G, Kessler MM, Mahajan-Miklos S, Pierce CM, Solinga RM, Sun LJ, Tobin JV, Kurtz CB, Currie MG.

Eur J Pharmacol · journal article · DOI 10.1016/j.ejphar.2010.09.019

Bibliografisk träff 2010-08-21

Optimized Fmoc solid-phase synthesis of the cysteine-rich peptide linaclotide.

Góngora-Benítez M, Tulla-Puche J, Paradís-Bas M, Werbitzky O, Giraud M, Albericio F.

Biopolymers · research support, non-u.s. gov't; journal article · DOI 10.1002/bip.21480

Bibliografisk träff 2010-03-20

Linaclotide is a potent and selective guanylate cyclase C agonist that elicits pharmacological effects locally in the gastrointestinal tract.

Bryant AP, Busby RW, Bartolini WP, Cordero EA, Hannig G, Kessler MM, Pierce CM, Solinga RM, Tobin JV, Mahajan-Miklos S, Cohen MB, Kurtz CB, Currie MG.

Life Sci · journal article · DOI 10.1016/j.lfs.2010.03.015

Bibliografisk träff 2010-03-01

Linaclotide - a secretagogue and antihyperalgesic agent - what next?

Bharucha AE, Linden DR.

Neurogastroenterol Motil · research-article; review; journal article; research support, n.i.h., extramural · DOI 10.1111/j.1365-2982.2009.01465.x

Bibliografisk träff 2009-08-25

Guanylate cyclase C-mediated antinociceptive effects of linaclotide in rodent models of visceral pain.

Eutamene H, Bradesi S, Larauche M, Theodorou V, Beaufrand C, Ohning G, Fioramonti J, Cohen M, Bryant AP, Kurtz C, Currie MG, Mayer EA, Bueno L.

Neurogastroenterol Motil · journal article · DOI 10.1111/j.1365-2982.2009.01385.x