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Publikationer i urvalet

28 träffar

Bibliografisk träff 2014-01-22

A photocleavable masked nuclear-receptor ligand enables temporal control of C. elegans development.

Judkins JC, Mahanti P, Hoffman JB, Yim I, Antebi A, Schroeder FC.

Angew Chem Int Ed Engl · research-article; journal article; research support, n.i.h., extramural · DOI 10.1002/anie.201307465

Bibliografisk träff 2014-01-01

Comparative metabolomics reveals endogenous ligands of DAF-12, a nuclear hormone receptor, regulating C. elegans development and lifespan.

Mahanti P, Bose N, Bethke A, Judkins JC, Wollam J, Dumas KJ, Zimmerman AM, Campbell SL, Hu PJ, Antebi A, Schroeder FC.

Cell Metab · comparative study; research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.cmet.2013.11.024

Bibliografisk träff 2013-10-10

Chemical signals synchronize the life cycles of a plant-parasitic nematode and its vector beetle.

Zhao L, Zhang S, Wei W, Hao H, Zhang B, Butcher RA, Sun J.

Curr Biol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.cub.2013.08.041

Bibliografisk träff 2013-09-19

Absolute quantification of a steroid hormone that regulates development in Caenorhabditis elegans.

Li TM, Chen J, Li X, Ding XJ, Wu Y, Zhao LF, Chen S, Lei X, Dong MQ.

Anal Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/ac402025c

Bibliografisk träff 2012-05-10

The Caenorhabditis elegans DAF-12 nuclear receptor: structure, dynamics, and interaction with ligands.

Alvarez LD, Mañez PA, Estrin DA, Burton G.

Proteins · research support, non-u.s. gov't; journal article · DOI 10.1002/prot.24076

Bibliografisk träff 2012-04-10

A novel 3-hydroxysteroid dehydrogenase that regulates reproductive development and longevity.

Wollam J, Magner DB, Magomedova L, Rass E, Shen Y, Rottiers V, Habermann B, Cummins CL, Antebi A.

PLoS Biol · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1371/journal.pbio.1001305

Bibliografisk träff 2012-04-10

Hormonal signal amplification mediates environmental conditions during development and controls an irreversible commitment to adulthood.

Schaedel ON, Gerisch B, Antebi A, Sternberg PW.

PLoS Biol · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1371/journal.pbio.1001306

Bibliografisk träff 2012-04-10

Steroids as central regulators of organismal development and lifespan.

Lee SS, Schroeder FC.

PLoS Biol · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1371/journal.pbio.1001307

Bibliografisk träff 2012-03-21

Stereoselective synthesis and hormonal activity of novel dafachronic acids and naturally occurring steroids isolated from corals.

Saini R, Boland S, Kataeva O, Schmidt AW, Kurzchalia TV, Knölker HJ.

Org Biomol Chem · research support, non-u.s. gov't; journal article · DOI 10.1039/c2ob25394a

Bibliografisk träff 2011-12-14

Structural conservation of ligand binding reveals a bile acid-like signaling pathway in nematodes.

Zhi X, Zhou XE, Melcher K, Motola DL, Gelmedin V, Hawdon J, Kliewer SA, Mangelsdorf DJ, Xu HE.

J Biol Chem · research-article; journal article; research support, n.i.h., extramural · DOI 10.1074/jbc.m111.315242

Bibliografisk träff 2011-08-07

The Rieske oxygenase DAF-36 functions as a cholesterol 7-desaturase in steroidogenic pathways governing longevity.

Wollam J, Magomedova L, Magner DB, Shen Y, Rottiers V, Motola DL, Mangelsdorf DJ, Cummins CL, Antebi A.

Aging Cell · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1111/j.1474-9726.2011.00733.x

Bibliografisk träff 2010-06-30

Co-option of the hormone-signalling module dafachronic acid-DAF-12 in nematode evolution.

Bento G, Ogawa A, Sommer RJ.

Nature · journal article · DOI 10.1038/nature09164

Bibliografisk träff 2010-05-01

Lipid transport and signaling in Caenorhabditis elegans.

Branicky R, Desjardins D, Liu JL, Hekimi S.

Dev Dyn · research support, non-u.s. gov't; review; journal article · DOI 10.1002/dvdy.22234

Bibliografisk träff 2010-02-21

Functional divergence of dafachronic acid pathways in the control of C. elegans development and lifespan.

Dumas KJ, Guo C, Wang X, Burkhart KB, Adams EJ, Alam H, Hu PJ.

Dev Biol · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.ydbio.2010.02.022

Bibliografisk träff 2009-12-03

Steroid hormones controlling the life cycle of the nematode Caenorhabditis elegans: stereoselective synthesis and biology.

Martin R, Entchev EV, Kurzchalia TV, Knölker HJ.

Org Biomol Chem · journal article · DOI 10.1039/b918488k

Bibliografisk träff 2009-06-02

Identification of the nuclear receptor DAF-12 as a therapeutic target in parasitic nematodes.

Wang Z, Zhou XE, Motola DL, Gao X, Suino-Powell K, Conneely A, Ogata C, Sharma KK, Auchus RJ, Lok JB, Hawdon JM, Kliewer SA, Xu HE, Mangelsdorf DJ.

Proc Natl Acad Sci U S A · research support, non-u.s. gov't; research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1073/pnas.0904064106

Bibliografisk träff 2009-06-01

Methylation of the sterol nucleus by STRM-1 regulates dauer larva formation in Caenorhabditis elegans.

Hannich JT, Entchev EV, Mende F, Boytchev H, Martin R, Zagoriy V, Theumer G, Riezman I, Riezman H, Knölker HJ, Kurzchalia TV.

Dev Cell · research support, non-u.s. gov't; journal article · DOI 10.1016/j.devcel.2009.04.012

Bibliografisk träff 2009-02-05

Synthesis and activity of dafachronic acid ligands for the C. elegans DAF-12 nuclear hormone receptor.

Sharma KK, Wang Z, Motola DL, Cummins CL, Mangelsdorf DJ, Auchus RJ.

Mol Endocrinol · research support, non-u.s. gov't; research-article; journal article · DOI 10.1210/me.2008-0415

Bibliografisk träff 2008-12-24

A conserved endocrine mechanism controls the formation of dauer and infective larvae in nematodes.

Ogawa A, Streit A, Antebi A, Sommer RJ.

Curr Biol · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.cub.2008.11.063

Bibliografisk träff 2008-10-17

Stereoselective synthesis of the hormonally active (25S)-delta7-dafachronic acid, (25S)-Delta4-dafachronic acid, (25S)-dafachronic acid, and (25S)-cholestenoic acid.

Martin R, Däbritz F, Entchev EV, Kurzchalia TV, Knölker HJ.

Org Biomol Chem · journal article · DOI 10.1039/b815064h

Bibliografisk träff 2008-07-19

Syntheses and biological evaluation of B-ring-modified analogues of dafachronic acid A.

Giroux S, Bethke A, Fielenbach N, Antebi A, Corey EJ.

Org Lett · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/ol801425v

Bibliografisk träff 2008-05-21

Genetic identification of HSD-1, a conserved steroidogenic enzyme that directs larval development in Caenorhabditis elegans.

Patel DS, Fang LL, Svy DK, Ruvkun G, Li W.

Development · research support, non-u.s. gov't; journal article; research support, n.i.h., extramural · DOI 10.1242/dev.016972

Bibliografisk träff 2008-02-05

An efficient, stereocontrolled synthesis of the 25-(R)-diastereomer of dafachronic acid A from beta-ergosterol.

Giroux S, Corey EJ.

Org Lett · research support, non-u.s. gov't; journal article · DOI 10.1021/ol702936f

Bibliografisk träff 2007-07-21

Stereocontrolled synthesis of dafachronic acid A, the ligand for the DAF-12 nuclear receptor of Caenorhabditis elegans.

Giroux S, Corey EJ.

J Am Chem Soc · research support, non-u.s. gov't; journal article · DOI 10.1021/ja074306i

Bibliografisk träff 2007-03-14

A bile acid-like steroid modulates Caenorhabditis elegans lifespan through nuclear receptor signaling.

Gerisch B, Rottiers V, Li D, Motola DL, Cummins CL, Lehrach H, Mangelsdorf DJ, Antebi A.

Proc Natl Acad Sci U S A · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1073/pnas.0700847104

Bibliografisk träff 2006-05-01

Small molecule signaling in Caenorhabditis elegans.

Schroeder FC.

ACS Chem Biol · review; journal article · DOI 10.1021/cb600173t

Bibliografisk träff 2006-03-09

Identification of ligands for DAF-12 that govern dauer formation and reproduction in C. elegans.

Motola DL, Cummins CL, Rottiers V, Sharma KK, Li T, Li Y, Suino-Powell K, Xu HE, Auchus RJ, Antebi A, Mangelsdorf DJ.

Cell · research support, non-u.s. gov't; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1016/j.cell.2006.01.037

Bibliografisk träff 2006-03-01

Indicted: worms caught using steroids.

Beckstead RB, Thummel CS.

Cell · review; journal article · DOI 10.1016/j.cell.2006.03.001