The 2014 Philip S. Portoghese Medicinal Chemistry Lectureship: The "Phenylalkylaminome" with a Focus on Selected Drugs of Abuse.
Glennon RA.
J Med Chem · research-article; journal article · DOI 10.1021/acs.jmedchem.7b00085 PUBLIKATIONSREGISTRET
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Publikationer i urvalet
16 träffarAn analysis of the synthetic tryptamines AMT and 5-MeO-DALT: emerging 'Novel Psychoactive Drugs'.
Arunotayanun W, Dalley JW, Huang XP, Setola V, Treble R, Iversen L, Roth BL, Gibbons S.
Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article; research support, n.i.h., extramural · DOI 10.1016/j.bmcl.2013.03.066Synthesis and serotonin transporter activity of 1,3-bis(aryl)-2-nitro-1-propenes as a new class of anticancer agents.
McNamara YM, Cloonan SM, Knox AJ, Keating JJ, Butler SG, Peters GH, Meegan MJ, Williams DC.
Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2010.11.054Synthesis and in vitro toxicity of 4-MTA, its characteristic clandestine synthesis byproducts and related sulfur substituted alpha-alkylthioamphetamines.
Cloonan SM, Keating JJ, Corrigan D, O'Brien JE, Kavanagh PV, Williams DC, Meegan MJ.
Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2010.04.022Synthesis and serotonin transporter activity of sulphur-substituted alpha-alkyl phenethylamines as a new class of anticancer agents.
Cloonan SM, Keating JJ, Butler SG, Knox AJ, Jørgensen AM, Peters GH, Rai D, Corrigan D, Lloyd DG, Williams DC, Meegan MJ.
Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2009.07.027The frontier orbital phase angles: novel QSAR descriptors for benzene derivatives, applied to phenylalkylamine hallucinogens.
Clare BW.
J Med Chem · journal article · DOI 10.1021/jm980144cSynthesis and pharmacological evaluation of ring-methylated derivatives of 3,4-(methylenedioxy)amphetamine (MDA).
Parker MA, Marona-Lewicka D, Kurrasch D, Shulgin AT, Nichols DE.
J Med Chem · comparative study; research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm9705925Synthesis and pharmacological examination of benzofuran, indan, and tetralin analogues of 3,4-(methylenedioxy)amphetamine.
Monte AP, Marona-Lewicka D, Cozzi NV, Nichols DE.
J Med Chem · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm00075a027Binding of phenylalkylamine derivatives at 5-HT1C and 5-HT2 serotonin receptors: evidence for a lack of selectivity.
Glennon RA, Raghupathi R, Bartyzel P, Teitler M, Leonhardt S.
J Med Chem · comparative study; journal article · DOI 10.1021/jm00082a014Structure-activity correlations for psychotomimetics. 1. Phenylalkylamines: electronic, volume, and hydrophobicity parameters.
Clare BW.
J Med Chem · comparative study; journal article · DOI 10.1021/jm00164a036Derivatives of 1-(1,3-benzodioxol-5-yl)-2-butanamine: representatives of a novel therapeutic class.
Nichols DE, Hoffman AJ, Oberlender RA, Jacob P, Shulgin AT.
J Med Chem · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm00160a035Photoelectron spectra of psychotropic drugs. 6. Relationships between the physical properties and pharmacological actions of amphetamine analogues.
Domelsmith LN, Eaton TA, Houk KN, Anderson GM, Glennon RA, Shulgin AT, Castagnoli N, Kollman PA.
J Med Chem · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm00144a009Serotonin receptor affinities of psychoactive phenalkylamine analogues.
Glennon RA, Liebowitz SM, Anderson GM.
J Med Chem · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm00177a017Steric effects of substituents on phenethylamine hallucinogens. 3,4-(Methylenedioxy)amphetamine analogues alkylated on the dioxole ring.
Nichols DE, Kostuba LJ.
J Med Chem · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm00196a022Serotonin receptor binding affinities of several hallucinogenic phenylalkylamine and N,N-dimethyltryptamine analogues.
Glennon RA, Liebowitz SM, Mack EC.
J Med Chem · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm00206a022Structure-activity studies on hallucinogenic amphetamines using molecular connectivity.
Kier LB, Hall LH.
J Med Chem · journal article · DOI 10.1021/jm00222a019