Recent advance on carbamate-based cholinesterase inhibitors as potential multifunctional agents against Alzheimer's disease.
Zhang H, Wang Y, Wang Y, Li X, Wang S, Wang Z.
Eur J Med Chem · review; journal article · DOI 10.1016/j.ejmech.2022.114606 PUBLIKATIONSREGISTRET
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9 träffarFatty Acid Amide Hydrolase (FAAH), Acetylcholinesterase (AChE), and Butyrylcholinesterase (BuChE): Networked Targets for the Development of Carbamates as Potential Anti-Alzheimer's Disease Agents.
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Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2011.02.071Novel carbamates as orally active acetylcholinesterase inhibitors found to improve scopolamine-induced cognition impairment: pharmacophore-based virtual screening, synthesis, and pharmacology.
Chaudhaery SS, Roy KK, Shakya N, Saxena G, Sammi SR, Nazir A, Nazir A, Nath C, Saxena AK.
J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm100573qInhibition of human acetyl- and butyrylcholinesterase by novel carbamates of (-)- and (+)-tetrahydrofurobenzofuran and methanobenzodioxepine.
Luo W, Yu QS, Kulkarni SS, Parrish DA, Holloway HW, Tweedie D, Shafferman A, Lahiri DK, Brossi A, Greig NH.
J Med Chem · research support, n.i.h., intramural; research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/jm050578pNovel anticholinesterases based on the molecular skeletons of furobenzofuran and methanobenzodioxepine.
Luo W, Yu QS, Zhan M, Parrish D, Deschamps JR, Kulkarni SS, Holloway HW, Alley GM, Lahiri DK, Brossi A, Greig NH.
J Med Chem · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm049309+Anticholinesterase activity of compounds related to geneserine tautomers. N-Oxides and 1,2-oxazines.
Yu QS, Zhu X, Holloway HW, Whittaker NF, Brossi A, Greig NH.
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Chen YL, Liston D, Nielsen J, Chapin D, Dunaiskis A, Hedberg K, Ives J, Johnson J, Jones S.
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