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Publikationer i urvalet

10 träffar

Bibliografisk träff 2013-03-24

Synthesis and biological evaluation of 2-(5-methyl-4-phenyl-2-oxopyrrolidin-1-yl)-acetamide stereoisomers as novel positive allosteric modulators of sigma-1 receptor.

Veinberg G, Vorona M, Zvejniece L, Vilskersts R, Vavers E, Liepinsh E, Kazoka H, Belyakov S, Mishnev A, Kuznecovs J, Vikainis S, Orlova N, Lebedev A, Ponomaryov Y, Dambrova M.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2013.03.016

Bibliografisk träff 2013-02-08

Synthesis and structure-activity relationship studies in serotonin 5-HT(1A) receptor agonists based on fused pyrrolidone scaffolds.

Cappelli A, Manini M, Valenti S, Castriconi F, Giuliani G, Anzini M, Brogi S, Butini S, Gemma S, Campiani G, Giorgi G, Mennuni L, Lanza M, Giordani A, Caselli G, Letari O, Makovec F.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2013.01.044

Bibliografisk träff 2013-01-16

Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells.

Germain AR, Carmody LC, Nag PP, Morgan B, Verplank L, Fernandez C, Donckele E, Feng Y, Perez JR, Dandapani S, Palmer M, Lander ES, Gupta PB, Schreiber SL, Munoz B.

Bioorg Med Chem Lett · journal article; research support, n.i.h., extramural · DOI 10.1016/j.bmcl.2013.01.025

Bibliografisk träff 2009-12-01

5-OHKF and NorKA, depsipeptides from a Hawaiian collection of Bryopsis pennata: binding properties for NorKA to the human neuropeptide Y Y1 receptor.

Gao J, Caballero-George C, Wang B, Rao KV, Shilabin AG, Hamann MT.

J Nat Prod · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/np900287e

Bibliografisk träff 2008-11-01

cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia.

Liu H, Altenbach RJ, Carr TL, Chandran P, Hsieh GC, Lewis LG, Manelli AM, Milicic I, Marsh KC, Miller TR, Strakhova MI, Vortherms TA, Wakefield BD, Wetter JM, Witte DG, Honore P, Esbenshade TA, Brioni JD, Cowart MD.

J Med Chem · journal article · DOI 10.1021/jm8007618

Bibliografisk träff 2008-06-28

Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activity.

Grice CA, Tays KL, Savall BM, Wei J, Butler CR, Axe FU, Bembenek SD, Fourie AM, Dunford PJ, Lundeen K, Coles F, Xue X, Riley JP, Williams KN, Karlsson L, Edwards JP.

J Med Chem · journal article · DOI 10.1021/jm701575k

Bibliografisk träff 2000-03-01

Transport function and hepatocellular localization of mrp6 in rat liver.

Madon J, Hagenbuch B, Landmann L, Meier PJ, Stieger B.

Mol Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1124/mol.57.3.634

Bibliografisk träff 1993-12-01

Endothelin-1 analogues substituted at both position 18 and 19: highly potent endothelin antagonists with no selectivity for either receptor subtype ETA or ETB.

Kikuchi T, Kubo K, Ohtaki T, Suzuki N, Asami T, Shimamoto N, Wakimasu M, Fujino M.

J Med Chem · journal article · DOI 10.1021/jm00077a013

Bibliografisk träff 1992-08-01

Design of a functional hexapeptide antagonist of endothelin.

Cody WL, Doherty AM, He JX, DePue PL, Rapundalo ST, Hingorani GA, Major TC, Panek RL, Dudley DT, Haleen SJ.

J Med Chem · journal article · DOI 10.1021/jm00095a029

Bibliografisk träff 1992-05-01

Endothelin: a new challenge.

Doherty AM.

J Med Chem · review; journal article · DOI 10.1021/jm00087a001