Recent advances and challenges of revolutionizing drug-resistant tuberculosis treatment.
Wei X, Yue L, Zhao B, Jiang N, Lei H, Zhai X.
Eur J Med Chem · review; journal article · DOI 10.1016/j.ejmech.2024.116785 PUBLIKATIONSREGISTRET
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16 träffarRecent advances in the exploration of oxazolidinone scaffolds from compound development to antibacterial agents and other bioactivities.
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J Med Chem · research support, non-u.s. gov't; review; journal article · DOI 10.1021/acs.jmedchem.3c01040Oxazolidinone: A promising scaffold for the development of antibacterial drugs.
Yuan S, Shen DD, Bai YR, Zhang M, Zhou T, Sun C, Zhou L, Wang SQ, Liu HM.
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Fernandes GFS, Thompson AM, Castagnolo D, Denny WA, Dos Santos JL.
J Med Chem · research support, non-u.s. gov't; review; journal article · DOI 10.1021/acs.jmedchem.2c00227Tuberculosis drug discovery: Progression and future interventions in the wake of emerging resistance.
Perveen S, Kumari D, Singh K, Sharma R.
Eur J Med Chem · review; journal article · DOI 10.1016/j.ejmech.2021.114066Discovery of a Conformationally Constrained Oxazolidinone with Improved Safety and Efficacy Profiles for the Treatment of Multidrug-Resistant Tuberculosis.
Zhao H, Wang B, Fu L, Li G, Lu H, Liu Y, Sheng L, Li Y, Zhang B, Lu Y, Ma C, Huang H, Zhang D, Lu Y.
J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jmedchem.0c00500Molecule Property Analyses of Active Compounds for <i>Mycobacterium tuberculosis</i>.
Makarov V, Salina E, Reynolds RC, Kyaw Zin PP, Ekins S.
J Med Chem · research support, non-u.s. gov't; research-article; review; journal article; research support, n.i.h., extramural · DOI 10.1021/acs.jmedchem.9b02075Effective Application of Metabolite Profiling in Drug Design and Discovery.
Cerny MA, Kalgutkar AS, Obach RS, Sharma R, Spracklin DK, Walker GS.
J Med Chem · journal article · DOI 10.1021/acs.jmedchem.9b01840Drug development against tuberculosis: Impact of alkaloids.
Mishra SK, Tripathi G, Kishore N, Singh RK, Singh A, Tiwari VK.
Eur J Med Chem · review; journal article · DOI 10.1016/j.ejmech.2017.06.005SAR analysis of new anti-TB drugs currently in pre-clinical and clinical development.
Poce G, Cocozza M, Consalvi S, Biava M.
Eur J Med Chem · review; journal article · DOI 10.1016/j.ejmech.2014.08.066Tuberculosis: the drug development pipeline at a glance.
Villemagne B, Crauste C, Flipo M, Baulard AR, Déprez B, Willand N.
Eur J Med Chem · review; journal article · DOI 10.1016/j.ejmech.2012.02.033Linezolid (ZYVOX), the first member of a completely new class of antibacterial agents for treatment of serious gram-positive infections.
Brickner SJ, Barbachyn MR, Hutchinson DK, Manninen PR.
J Med Chem · review; journal article · DOI 10.1021/jm800038gNew small-molecule synthetic antimycobacterials.
Ballell L, Field RA, Duncan K, Young RJ.
Antimicrob Agents Chemother · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; review-article; review; journal article · DOI 10.1128/aac.49.6.2153-2163.2005Synthesis and in vitro antimycobacterial activity of novel 3-(1H-pyrrol-1-yl)-2-oxazolidinone analogues of PNU-100480.
Sbardella G, Mai A, Artico M, Loddo R, Setzu MG, La Colla P.
Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2004.01.010Identification of a novel oxazolidinone (U-100480) with potent antimycobacterial activity.
Barbachyn MR, Hutchinson DK, Brickner SJ, Cynamon MH, Kilburn JO, Klemens SP, Glickman SE, Grega KC, Hendges SK, Toops DS, Ford CW, Zurenko GE.
J Med Chem · journal article · DOI 10.1021/jm950956y