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Publikationer i urvalet

21 träffar

Bibliografisk träff 2018-06-20

Discovery of Novel Topoisomerase II Inhibitors by Medicinal Chemistry Approaches.

Hu W, Huang XS, Wu JF, Yang L, Zheng YT, Shen YM, Li ZY, Li X.

J Med Chem · research support, non-u.s. gov't; review; journal article · DOI 10.1021/acs.jmedchem.7b01202

Bibliografisk träff 2017-03-11

Indenocinnoline derivatives as G-quadruplex binders, topoisomerase IIα inhibitors and antiproliferative agents.

Zoidis G, Sosic A, Da Ros S, Gatto B, Sissi C, Palluotto F, Carotti A, Catto M.

Bioorg Med Chem · journal article · DOI 10.1016/j.bmc.2017.03.019

Bibliografisk träff 2016-07-28

Quinolino[3,4-b]quinoxalines and pyridazino[4,3-c]quinoline derivatives: Synthesis, inhibition of topoisomerase IIα, G-quadruplex binding and cytotoxic properties.

Palluotto F, Sosic A, Pinato O, Zoidis G, Catto M, Sissi C, Gatto B, Carotti A.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2016.07.063

Bibliografisk träff 2008-10-04

Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.

Santana L, González-Díaz H, Quezada E, Uriarte E, Yáñez M, Viña D, Orallo F.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm800656v

Bibliografisk träff 2007-10-10

Synthesis, DNA binding, and cytotoxicity of 1,4-bis(2-amino-ethylamino)anthraquinone-amino acid conjugates.

Hsin LW, Wang HP, Kao PH, Lee O, Chen WR, Chen HW, Guh JH, Chan YL, His CP, Yang MS, Li TK, Lee CH.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2007.10.012

Bibliografisk träff 1999-09-01

8,11-dihydroxy-6-[(aminoalkyl)amino]-7H-benzo[e]perimidin-7-ones with activity in multidrug-resistant cell lines: synthesis and antitumor evaluation.

Stefańska B, Dzieduszycka M, Bontemps-Gracz MM, Borowski E, Martelli S, Supino R, Pratesi G, De Cesare M, Zunino F, Kuśnierczyk H, Radzikowski C.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm980682p

Bibliografisk träff 1996-08-01

Peptidyl anthraquinones as potential antineoplastic drugs: synthesis, DNA binding, redox cycling, and biological activity.

Gatto B, Zagotto G, Sissi C, Cera C, Uriarte E, Palù G, Capranico G, Palumbo M.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm950924a

Bibliografisk träff 1995-02-01

Chromophore-modified antitumor anthracenediones: synthesis, DNA binding, and cytotoxic activity of 1,4-bis[(aminoalkyl)amino]benzo[g]-phthalazine-5,10-diones.

Gandolfi CA, Beggiolin G, Menta E, Palumbo M, Sissi C, Spinelli S, Johnson F.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm00003a015

Bibliografisk träff 1994-03-01

6,9-Bis[(aminoalkyl)amino]benzo[g]isoquinoline-5,10-diones. A novel class of chromophore-modified antitumor anthracene-9,10-diones: synthesis and antitumor evaluations.

Krapcho AP, Petry ME, Getahun Z, Landi JJ, Stallman J, Polsenberg JF, Gallagher CE, Maresch MJ, Hacker MP, Giuliani FC.

J Med Chem · comparative study; journal article · DOI 10.1021/jm00032a018

Bibliografisk träff 1993-01-01

6-[(aminoalkyl)amino]-substituted 7H-benzo[e]perimidin-7-ones as novel antineoplastic agents. Synthesis and biological evaluation.

Stefańska B, Dzieduszycka M, Martelli S, Tarasiuk J, Bontemps-Gracz M, Borowski E.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm00053a005

Bibliografisk träff 1992-01-01

Chromophore-modified antineoplastic imidazoacridinones. Synthesis and activity against murine leukemias.

Cholody WM, Martelli S, Konopa J.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm00080a026

Bibliografisk träff 1991-08-01

Synthesis and antitumor evaluations of symmetrically and unsymmetrically substituted 1,4-bis[(aminoalkyl)amino]anthracene-9,10-diones and 1,4-bis[(aminoalkyl)amino]-5,8-dihydroxyanthracene-9,10-diones.

Krapcho AP, Getahun Z, Avery KL, Vargas KJ, Hacker MP, Spinelli S, Pezzoni G, Manzotti C.

J Med Chem · comparative study; journal article · DOI 10.1021/jm00112a009

Bibliografisk träff 1991-02-01

Synthesis, peroxidating ability, and antineoplastic evaluation of 1-[(aminoalkyl)amino]-4-hydroxy-10-imino-9-anthracenones.

Dzieduszycka M, Martelli S, Tarasiuk J, Paradziej-Lukowicz J, Borowski E.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm00106a009

Bibliografisk träff 1990-10-01

8-Substituted 5-[(aminoalkyl)amino]-6H-v-triazolo[4,5,1-de]acridin-6-ones as potential antineoplastic agents. Synthesis and biological activity.

Cholody WM, Martelli S, Konopa J.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm00172a028

Bibliografisk träff 1990-09-01

Heterosubstituted anthracene-9,10-dione analogues. The synthesis and antitumor evaluation of 5,8-bis[(aminoalkyl)amino]naphtho[2,3-b] thiophene-4,9-diones.

Krapcho AP, Petry ME, Hacker MP.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm00171a048

Bibliografisk träff 1989-08-01

Synthesis of unsymmetrically substituted 1,4-bis[(aminoalkyl)amino]anthracene-9,10-diones as potential antileukemic agents.

Stefanska B, Dzieduszycka M, Martelli S, Borowski E.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm00128a009

Bibliografisk träff 1988-10-01

Synthesis and antineoplastic evaluation of 1,4-bis(aminoalkanamido)-9,10-anthracenediones.

Martelli S, Dzieduszycka M, Stefanska B, Bontemps-Gracz M, Borowski E.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm00118a015

Bibliografisk träff 1984-04-01

Interactions of antitumor drugs with natural DNA: 1H NMR study of binding mode and kinetics.

Feigon J, Denny WA, Leupin W, Kearns DR.

J Med Chem · comparative study; research support, non-u.s. gov't; journal article · DOI 10.1021/jm00370a007

Bibliografisk träff 1979-09-01

Antitumor agents. 1. 1,4-Bis[(aminoalkyl)amino]-9,10-anthracenediones.

Murdock KC, Child RG, Fabio PF, Angier RB, Wallace RE, Durr FE, Citarella RV.

J Med Chem · journal article · DOI 10.1021/jm00195a002

Bibliografisk träff 1979-05-01

Structural modification study of bis(substituted aminoalkylamino)anthraquinones. An evaluation of the relationship of the [2-[(2-hydroxyethyl)amino]ethyl]amino side chain with antineoplastic activity.

Zee-Cheng RK, Podrebarac EG, Menon CS, Cheng CC.

J Med Chem · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm00191a008

Bibliografisk träff 1978-03-01

Antineoplastic agents. Structure-activity relationship study of bis(substituted aminoalkylamino)anthraquinones.

Zee-Cheng RK, Cheng CC.

J Med Chem · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm00201a012