Natural Product-Inspired Dopamine Receptor Ligands.
Dorogan M, Namballa HK, Harding WW.
J Med Chem · review-article; review; journal article · DOI 10.1021/acs.jmedchem.4c00537 PUBLIKATIONSREGISTRET
Gå till forskningen.
Publikationsdata från Europe PMC och PubMed. Följ källhänvisningar från ämnesregistret till originalpublikationerna.
Publikationer som ChEBI hänvisar till för ecopipam. Visa hela publikationsregistret
En publikationsträff är inte en slutsats. Publikationslistan visar bibliografiska uppgifter. Eventuella forskningsutdrag visas separat med originalunderlag. En källhänvisning visar inte i sig effekt, dosering eller säkerhet.
Publikationer i urvalet
9 träffarSynthesis and pharmacological evaluation of 11-(1,6-dimethyl-1,2,3,6-tetrahydropyridin-4-yl)-5H-dibenzo[b,e][1,4]diazepines with clozapine-like receptor occupancy at dopamine D<sub>1</sub>/D<sub>2</sub> receptor.
Watanabe H, Ishida K, Yamamoto M, Horiguchi M, Isobe Y.
Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2020.127563Discovery of new SCH 39166 analogs as potent and selective dopamine D1 receptor antagonists.
Qiang L, Sasikumar TK, Burnett DA, Su J, Tang H, Ye Y, Mazzola RD, Zhu Z, McKittrick BA, Greenlee WJ, Fawzi A, Smith M, Zhang H, Lachowicz JE.
Bioorg Med Chem Lett · comparative study; journal article · DOI 10.1016/j.bmcl.2009.12.100Remote functionalization of SCH 39166: discovery of potent and selective benzazepine dopamine D1 receptor antagonists.
Sasikumar TK, Burnett DA, Greenlee WJ, Smith M, Fawzi A, Zhang H, Lachowicz JE.
Bioorg Med Chem Lett · comparative study; journal article · DOI 10.1016/j.bmcl.2009.12.094Dopamine D1/D5 receptor antagonists with improved pharmacokinetics: design, synthesis, and biological evaluation of phenol bioisosteric analogues of benzazepine D1/D5 antagonists.
Wu WL, Burnett DA, Spring R, Greenlee WJ, Smith M, Favreau L, Fawzi A, Zhang H, Lachowicz JE.
J Med Chem · journal article · DOI 10.1021/jm030614pHuman UDP-glucuronosyltransferases: metabolism, expression, and disease.
Tukey RH, Strassburg CP.
Annu Rev Pharmacol Toxicol · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; review; journal article · DOI 10.1146/annurev.pharmtox.40.1.581A study on the contribution of the 1-phenyl substituent to the molecular electrostatic potentials of some benzazepines in relation to selective dopamine D-1 receptor activity.
Pettersson I, Gundertofte K, Palm J, Liljefors T.
J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm00081a010Conformational analysis and structure-activity relationships of selective dopamine D-1 receptor agonists and antagonists of the benzazepine series.
Pettersson I, Liljefors T, Bøgesø K.
J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm00170a025Synthesis and receptor affinities of some conformationally restricted analogues of the dopamine D1 selective ligand (5R)-8-chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl- 1H-3-benzazepin-7-ol.
Berger JG, Chang WK, Clader JW, Hou D, Chipkin RE, McPhail AT.
J Med Chem · journal article · DOI 10.1021/jm00128a038