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Publikationer i urvalet

14 träffar

Bibliografisk träff 2023-07-19

A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.

Sutherland JJ, Yonchev D, Fekete A, Urban L.

Nat Commun · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/s41467-023-40064-9

Bibliografisk träff 2020-06-10

SAR of non-hydrolysable analogs of pyridoxal 5'-phosphate against low molecular weight protein tyrosine phosphatase isoforms.

DeSouza SR, Olson MC, Tinucci SL, Sinner EK, Flynn RS, Marshall QF, Jakubowski HV, McIntee EJ.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2020.127342

Bibliografisk träff 2018-08-31

The synthesis and kinetic evaluation of aryl α-aminophosphonates as novel inhibitors of T. cruzi trans-sialidase.

Chen Z, Marcé P, Resende R, Alzari PM, Frasch AC, van den Elsen JMH, Crennell SJ, Watts AG.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2018.08.089

Bibliografisk träff 2014-08-07

Design, synthesis and enzymatic evaluation of 3-O-substituted aryl β-D-galactopyranosides as inhibitors of Trypanosoma cruzi trans-sialidase.

Silva BL, S Filho JD, Andrade P, Carvalho I, Alves RJ.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2014.07.088

Bibliografisk träff 2013-08-27

Identification of new inhibitors for low molecular weight protein tyrosine phosphatase isoform B.

Seiler CL, Richards KA, Jakubowski HV, McIntee EJ.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2013.08.079

Bibliografisk träff 2013-02-22

Synthesis and structure-activity relationships of carboxylic acid derivatives of pyridoxal as P2X receptor antagonists.

Jung KY, Cho JH, Lee JS, Kim HJ, Kim YC.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2013.01.073

Bibliografisk träff 2011-09-05

Vitamin B6s inhibit oxidative stress caused by Alzheimer's disease-related Cu(II)-β-amyloid complexes-cooperative action of phospho-moiety.

Hashim A, Wang L, Juneja K, Ye Y, Zhao Y, Ming LJ.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2011.08.123

Bibliografisk träff 2010-03-02

'Click chemistry' synthesis of a library of 1,2,3-triazole-substituted galactose derivatives and their evaluation against Trypanosoma cruzi and its cell surface trans-sialidase.

Carvalho I, Andrade P, Campo VL, Guedes PM, Sesti-Costa R, Silva JS, Schenkman S, Dedola S, Hill L, Rejzek M, Nepogodiev SA, Field RA.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2010.02.053

Bibliografisk träff 2010-01-01

Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.

Fourches D, Barnes JC, Day NC, Bradley P, Reed JZ, Tropsha A.

Chem Res Toxicol · research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1021/tx900326k

Bibliografisk träff 2008-12-24

Discovery of novel inhibitors of Trypanosoma cruzi trans-sialidase from in silico screening.

Neres J, Brewer ML, Ratier L, Botti H, Buschiazzo A, Edwards PN, Mortenson PN, Charlton MH, Alzari PM, Frasch AC, Bryce RA, Douglas KT.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2008.12.065

Bibliografisk träff 2004-09-01

Pyridoxine as a template for the design of antiplatelet agents.

Zhang W, Yao J, Pham V, Whitney T, Froese D, Friesen A, Stang L, Xu C, Shuaib A, Diakur JM, Haque W.

Bioorg Med Chem Lett · comparative study; journal article · DOI 10.1016/j.bmcl.2004.06.079

Bibliografisk träff 2003-08-01

Design and synthesis of novel pyridoxine 5'-phosphonates as potential antiischemic agents.

Pham V, Zhang W, Chen V, Whitney T, Yao J, Froese D, Friesen AD, Diakur JM, Haque W.

J Med Chem · journal article · DOI 10.1021/jm0300678

Bibliografisk träff 2002-09-01

Purine and pyrimidine (P2) receptors as drug targets.

Jacobson KA, Jarvis MF, Williams M.

J Med Chem · research support, u.s. gov't, p.h.s.; research-article; review; journal article · DOI 10.1021/jm020046y

Bibliografisk träff 1983-04-01

Phosphonate analogues of pyridoxal phosphate with shortened side chains.

Han CN, Iwata C, Metzler DE.

J Med Chem · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm00358a027