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Publikationer som ChEBI hänvisar till för pafuramidine. Visa hela publikationsregistret

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Publikationer i urvalet

15 träffar

Bibliografisk träff 2016-12-23

Synthesis, biological characterisation and structure activity relationships of aromatic bisamidines active against Plasmodium falciparum.

Sauer B, Skinner-Adams TS, Bouchut A, Chua MJ, Pierrot C, Erdmann F, Robaa D, Schmidt M, Khalife J, Andrews KT, Sippl W.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2016.12.041

Bibliografisk träff 2016-03-03

DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.

Chen M, Suzuki A, Thakkar S, Yu K, Hu C, Tong W.

Drug Discov Today · review; journal article · DOI 10.1016/j.drudis.2016.02.015

Bibliografisk träff 2013-08-13

Synthesis and antiprotozoal activity of dicationic 2,6-diphenylpyrazines and aza-analogues.

Hu L, Patel A, Bondada L, Yang S, Wang MZ, Munde M, Wilson WD, Wenzler T, Brun R, Boykin DW.

Bioorg Med Chem · research-article; journal article · DOI 10.1016/j.bmc.2013.08.006

Bibliografisk träff 2011-12-15

Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Liu Z, Shi Q, Ding D, Kelly R, Fang H, Tong W.

PLoS Comput Biol · research support, u.s. gov't, p.h.s.; research-article; journal article · DOI 10.1371/journal.pcbi.1002310

Bibliografisk träff 2011-05-20

FDA-approved drug labeling for the study of drug-induced liver injury.

Chen M, Vijay V, Shi Q, Liu Z, Fang H, Tong W.

Drug Discov Today · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1016/j.drudis.2011.05.007

Bibliografisk träff 2010-03-27

Synthesis and antiprotozoal activity of 2,5-bis[amidinoaryl]thiazoles.

Branowska D, Farahat AA, Kumar A, Wenzler T, Brun R, Liu Y, Wilson WD, Boykin DW.

Bioorg Med Chem · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.bmc.2010.03.058

Bibliografisk träff 2010-01-01

Synthesis and antiprotozoal activity of cationic 1,4-diphenyl-1H-1,2,3-triazoles.

Bakunov SA, Bakunova SM, Wenzler T, Ghebru M, Werbovetz KA, Brun R, Tidwell RR.

J Med Chem · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/jm901178d

Bibliografisk träff 2009-07-20

New treatment option for second-stage African sleeping sickness: in vitro and in vivo efficacy of aza analogs of DB289.

Wenzler T, Boykin DW, Ismail MA, Hall JE, Tidwell RR, Brun R.

Antimicrob Agents Chemother · research support, non-u.s. gov't; research-article; journal article · DOI 10.1128/aac.00225-09

Bibliografisk träff 2008-12-08

Efficacy of the novel diamidine compound 2,5-Bis(4-amidinophenyl)- furan-bis-O-Methlylamidoxime (Pafuramidine, DB289) against Trypanosoma brucei rhodesiense infection in vervet monkeys after oral administration.

Mdachi RE, Thuita JK, Kagira JM, Ngotho JM, Murilla GA, Ndung'u JM, Tidwell RR, Hall JE, Brun R.

Antimicrob Agents Chemother · research support, non-u.s. gov't; research-article; journal article · DOI 10.1128/aac.00831-08

Bibliografisk träff 2007-10-18

Synthesis and antiprotozoal activity of novel bis-benzamidino imidazo[1,2-a]pyridines and 5,6,7,8-tetrahydro-imidazo[1,2-a]pyridines.

Ismail MA, Arafa RK, Wenzler T, Brun R, Tanious FA, Wilson WD, Boykin DW.

Bioorg Med Chem · research support, non-u.s. gov't; journal article; research support, n.i.h., extramural · DOI 10.1016/j.bmc.2007.10.042

Bibliografisk träff 2007-04-03

Carbamate prodrugs of N-alkylfuramidines.

Rahmathullah SM, Tidwell RR, Jones SK, Hall JE, Boykin DW.

Eur J Med Chem · journal article; research support, n.i.h., extramural · DOI 10.1016/j.ejmech.2007.03.009

Bibliografisk träff 2006-08-01

Synthesis, DNA affinity, and antiprotozoal activity of linear dications: Terphenyl diamidines and analogues.

Ismail MA, Arafa RK, Brun R, Wenzler T, Miao Y, Wilson WD, Generaux C, Bridges A, Hall JE, Boykin DW.

J Med Chem · research support, non-u.s. gov't; journal article; research support, n.i.h., extramural · DOI 10.1021/jm060470p

Bibliografisk träff 2004-08-01

O-alkoxyamidine prodrugs of furamidine: in vitro transport and microsomal metabolism as indicators of in vivo efficacy in a mouse model of Trypanosoma brucei rhodesiense infection.

Ansede JH, Anbazhagan M, Brun R, Easterbrook JD, Hall JE, Boykin DW.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm030604o

Bibliografisk träff 2004-07-01

Novel dicationic imidazo[1,2-a]pyridines and 5,6,7,8-tetrahydro-imidazo[1,2-a]pyridines as antiprotozoal agents.

Ismail MA, Brun R, Wenzler T, Tanious FA, Wilson WD, Boykin DW.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm0400092

Bibliografisk träff 2003-10-01

Synthesis and antiprotozoal activity of aza-analogues of furamidine.

Ismail MA, Brun R, Easterbrook JD, Tanious FA, Wilson WD, Boykin DW.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm0302602