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Publikationer i urvalet

6 träffar

Bibliografisk träff 2022-08-27

Chemical similarities and differences among inhibitors of nitric oxide synthase, arginase and dimethylarginine dimethylaminohydrolase-1: Implications for the design of novel enzyme inhibitors modulating the nitric oxide pathway.

Doman AJ, Tommasi S, Perkins MV, McKinnon RA, Mangoni AA, Nair PC.

Bioorg Med Chem · review; journal article · DOI 10.1016/j.bmc.2022.116970

Bibliografisk träff 2011-05-30

Novel nanomolar imidazo[4,5-b]pyridines as selective nitric oxide synthase (iNOS) inhibitors: SAR and structural insights.

Grädler U, Fuchss T, Ulrich WR, Boer R, Strub A, Hesslinger C, Anézo C, Diederichs K, Zaliani A.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2011.05.073

Bibliografisk träff 2011-03-21

Heteroalicyclic carboxamidines as inhibitors of inducible nitric oxide synthase; the identification of (2R)-2-pyrrolidinecarboxamidine as a potent and selective haem-co-ordinating inhibitor.

Young RJ, Alderton W, Angell AD, Beswick PJ, Brown D, Chambers CL, Crowe MC, Dawson J, Hamlett CC, Hodgson ST, Kleanthous S, Knowles RG, Russell LJ, Stocker R, Woolven JM.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2011.03.038

Bibliografisk träff 2007-10-25

Discovery of a series of aminopiperidines as novel iNOS inhibitors.

Le Bourdonnec B, Leister LK, Ajello CA, Cassel JA, Seida PR, O'Hare H, Gu M, Chu GH, Tuthill PA, DeHaven RN, Dolle RE.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2007.10.073

Bibliografisk träff 2004-06-01

2-aminopyridines as highly selective inducible nitric oxide synthase inhibitors. Differential binding modes dependent on nitrogen substitution.

Connolly S, Aberg A, Arvai A, Beaton HG, Cheshire DR, Cook AR, Cooper S, Cox D, Hamley P, Mallinder P, Millichip I, Nicholls DJ, Rosenfeld RJ, St-Gallay SA, Tainer J, Tinker AC, Wallace AV.

J Med Chem · journal article · DOI 10.1021/jm031035n

Bibliografisk träff 2000-03-01

Inhibition of inducible nitric oxide synthase by acetamidine derivatives of hetero-substituted lysine and homolysine.

Young RJ, Beams RM, Carter K, Clark HA, Coe DM, Chambers CL, Davies PI, Dawson J, Drysdale MJ, Franzman KW, French C, Hodgson ST, Hodson HF, Kleanthous S, Rider P, Sanders D, Sawyer DA, Scott KJ, Shearer BG, Stocker R, Smith S, Tackley MC, Knowles RG.

Bioorg Med Chem Lett · journal article · DOI 10.1016/s0960-894x(00)00055-x