Design, synthesis, and physicochemical properties of a novel, conformationally restricted 2,3-dihydro-1,3,4-thiadiazole-containing angiotensin converting enzyme inhibitor which is preferentially eliminated by the biliary route in rats.
Bennion C, Brown RC, Cook AR, Manners CN, Payling DW, Robinson DH.
J Med Chem · comparative study; journal article · DOI 10.1021/jm00105a066