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Publikationer i urvalet

10 träffar

Bibliografisk träff 2020-05-05

p62/SQSTM1, a Central but Unexploited Target: Advances in Its Physiological/Pathogenic Functions and Small Molecular Modulators.

Chen Y, Li Q, Li Q, Xing S, Liu Y, Liu Y, Chen Y, Liu W, Feng F, Sun H.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jmedchem.9b02038

Bibliografisk träff 2013-04-09

Structure-based identification of OATP1B1/3 inhibitors.

De Bruyn T, van Westen GJ, Ijzerman AP, Stieger B, de Witte P, Augustijns PF, Annaert PP.

Mol Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1124/mol.112.084152

Bibliografisk träff 2012-05-14

Liver-stage malaria parasites vulnerable to diverse chemical scaffolds.

Derbyshire ER, Prudêncio M, Mota MM, Clardy J.

Proc Natl Acad Sci U S A · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1073/pnas.1118370109

Bibliografisk träff 2010-10-21

Identification of clinically used drugs that activate pregnane X receptors.

Shukla SJ, Sakamuru S, Huang R, Moeller TA, Shinn P, Vanleer D, Auld DS, Austin CP, Xia M.

Drug Metab Dispos · research support, n.i.h., intramural; research-article; journal article · DOI 10.1124/dmd.110.035105

Bibliografisk träff 2009-09-06

Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Yuan J, Johnson RL, Huang R, Wichterman J, Jiang H, Hayton K, Fidock DA, Wellems TE, Inglese J, Austin CP, Su XZ.

Nat Chem Biol · research support, n.i.h., intramural; research-article; journal article; research support, n.i.h., extramural · DOI 10.1038/nchembio.215

Bibliografisk träff 2007-04-08

Chemical genetics reveals a complex functional ground state of neural stem cells.

Diamandis P, Wildenhain J, Clarke ID, Sacher AG, Graham J, Bellows DS, Ling EK, Ward RJ, Jamieson LG, Tyers M, Dirks PB.

Nat Chem Biol · research support, non-u.s. gov't; journal article · DOI 10.1038/nchembio873

Bibliografisk träff 1987-02-01

Molecular modification of anticholinergics as probes for muscarinic receptors. 1. Amino esters of alpha-substituted phenylacetic acid and related analogues.

Lu MC, Wung WE, Shih LB, Callejas S, Gearien JE, Thompson EB.

J Med Chem · comparative study; journal article · DOI 10.1021/jm00385a008

Bibliografisk träff 1982-06-01

Inhibitors of hepatic mixed-function oxidases. 4. Effects of benzimidazole and related compounds on aryl hydrocarbon hydroxylase activity from phenobarbitone and 3-methylcholanthrene induced rats.

Little PJ, Ryan AJ.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm00348a003

Bibliografisk träff 1977-11-01

Hypolipidemic analogues of ethyl 4-benzyloxybenzoate.

Baggaley KH, Fears R, Hindley RM, Morgan B, Murrell E, Thorne DE.

J Med Chem · journal article · DOI 10.1021/jm00221a007

Bibliografisk träff 1977-09-01

Inhibitors of hepatic mixed function oxidase. 3. Inhibition of hepatic microsomal aniline hydroxylase and aminopyrine demethylase by 2,6- and 2,4-dihydroxyphenyl alkyl ketones and related compounds.

Bobik A, Holder GM, Ryan AJ.

J Med Chem · journal article · DOI 10.1021/jm00219a017