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Publikationer i urvalet

10 träffar

Bibliografisk träff 2015-05-15

Design, synthesis and biological evaluation of a novel series of peripheral-selective noradrenaline reuptake inhibitor.

Fujimori I, Yukawa T, Kamei T, Nakada Y, Sakauchi N, Yamada M, Ohba Y, Takiguchi M, Kuno M, Kamo I, Nakagawa H, Hamada T, Igari T, Okuda T, Yamamoto S, Tsukamoto T, Ishichi Y, Ueno H.

Bioorg Med Chem · journal article · DOI 10.1016/j.bmc.2015.05.017

Bibliografisk träff 2012-12-22

A novel class of 3-(phenoxy-phenyl-methyl)-pyrrolidines as potent and balanced norepinephrine and serotonin reuptake inhibitors: synthesis and structure-activity relationships.

Van Orden LJ, Van Dyke PM, Saito DR, Church TJ, Chang R, Smith JA, Martin WJ, Jaw-Tsai S, Stangeland EL.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2012.12.061

Bibliografisk träff 2009-09-18

Dual acting norepinephrine reuptake inhibitors and 5-HT(2A) receptor antagonists: Identification, synthesis and activity of novel 4-aminoethyl-3-(phenylsulfonyl)-1H-indoles.

Heffernan GD, Coghlan RD, Manas ES, McDevitt RE, Li Y, Mahaney PE, Robichaud AJ, Huselton C, Alfinito P, Bray JA, Cosmi SA, Johnston GH, Kenney T, Koury E, Winneker RC, Deecher DC, Trybulski EJ.

Bioorg Med Chem · journal article · DOI 10.1016/j.bmc.2009.09.023

Bibliografisk träff 2009-09-01

1- or 3-(3-Amino-2-hydroxy-1-phenyl propyl)-1,3-dihydro-2H-benzimidazol-2-ones: potent, selective, and orally efficacious norepinephrine reuptake inhibitors.

Zhang P, Terefenko EA, Bray J, Deecher D, Fensome A, Harrison J, Kim C, Koury E, Mark L, McComas CC, Mugford CA, Trybulski EJ, Vu AT, Whiteside GT, Mahaney PE.

J Med Chem · journal article · DOI 10.1021/jm900888c

Bibliografisk träff 2009-01-01

Synthesis, radiosynthesis, and biological evaluation of carbon-11 and fluorine-18 labeled reboxetine analogues: potential positron emission tomography radioligands for in vivo imaging of the norepinephrine transporter.

Zeng F, Mun J, Jarkas N, Stehouwer JS, Voll RJ, Tamagnan GD, Howell L, Votaw JR, Kilts CD, Nemeroff CB, Goodman MM.

J Med Chem · research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1021/jm800817h

Bibliografisk träff 2008-12-16

Molecular properties of psychopharmacological drugs determining non-competitive inhibition of 5-HT3A receptors.

Kornhuber J, Terfloth L, Bleich S, Wiltfang J, Rupprecht R.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2008.12.003

Bibliografisk träff 2008-07-17

Structure-activity relationships of chiral selective norepinephrine reuptake inhibitors (sNRI) with increased oxidative stability.

Hudson S, Kiankarimi M, Eccles W, Dwight W, Mostofi YS, Genicot MJ, Fleck BA, Gogas K, Aparicio A, Wang H, Wen J, Wade WS.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2008.07.049

Bibliografisk träff 2008-05-23

Studies on the structure-activity relationship of bicifadine analogs as monoamine transporter inhibitors.

Zhang M, Jovic F, Vickers T, Dyck B, Tamiya J, Grey J, Tran JA, Fleck BA, Pick R, Foster AC, Chen C.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2008.05.077

Bibliografisk träff 2007-11-21

Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.

Kornhuber J, Tripal P, Reichel M, Terfloth L, Bleich S, Wiltfang J, Gulbins E.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm070524a

Bibliografisk träff 2005-02-01

Discovery and structure-activity relationships of novel selective norepinephrine and dual serotonin/norepinephrine reuptake inhibitors.

Boot J, Cases M, Clark BP, Findlay J, Gallagher PT, Hayhurst L, Man T, Montalbetti C, Rathmell RE, Rudyk H, Walter MW, Whatton M, Wood V.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2004.11.025