Imaging probes of tau pathology.
Rosse G.
ACS Med Chem Lett · editorial; journal article · DOI 10.1021/ml400276w PUBLIKATIONSREGISTRET
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Publikationer i urvalet
23 träffarContributions of academic laboratories to the discovery and development of chemical biology tools.
Huryn DM, Resnick LO, Wipf P.
J Med Chem · research-article; review; journal article; research support, n.i.h., extramural · DOI 10.1021/jm400132dProgress and developments in tau aggregation inhibitors for Alzheimer disease.
Bulic B, Pickhardt M, Mandelkow E.
J Med Chem · research support, non-u.s. gov't; review; journal article · DOI 10.1021/jm3017317¹⁸F-labeled 2-phenylquinoxaline derivatives as potential positron emission tomography probes for in vivo imaging of β-amyloid plaques.
Yu P, Cui M, Wang X, Zhang X, Li Z, Yang Y, Jia J, Zhang J, Ono M, Saji H, Jia H, Liu B.
Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2012.08.031The β-Amyloid Hypothesis in Alzheimer's Disease: Seeing Is Believing.
Kung HF.
ACS Med Chem Lett · editorial; journal article · DOI 10.1021/ml300058mMultidentate (18)F-polypegylated styrylpyridines as imaging agents for Aβ plaques in cerebral amyloid angiopathy (CAA).
Zha Z, Choi SR, Ploessl K, Lieberman BP, Qu W, Hefti F, Mintun M, Skovronsky D, Kung HF.
J Med Chem · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/jm2009106Synthesis and evaluation of 1-(4-[¹⁸F]fluoroethyl)-7-(4'-methyl)curcumin with improved brain permeability for β-amyloid plaque imaging.
Lee I, Yang J, Lee JH, Choe YS.
Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2011.08.003A Novel (18)F-Labeled Imidazo[2,1-b]benzothiazole (IBT) for High-Contrast PET Imaging of β-Amyloid Plaques.
Yousefi BH, Drzezga A, von Reutern B, Manook A, Schwaiger M, Wester HJ, Henriksen G.
ACS Med Chem Lett · rapid-communication; journal article · DOI 10.1021/ml200123w2-Arylimidazo[2,1-b]benzothiazoles: a new family of amyloid binding agents with potential for PET and SPECT imaging of Alzheimer's brain.
Alagille D, DaCosta H, Baldwin RM, Tamagnan GD.
Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2011.03.052Synthesis and evaluation of 11C-labeled imidazo[2,1-b]benzothiazoles (IBTs) as PET tracers for imaging β-amyloid plaques in Alzheimer's disease.
Yousefi BH, Manook A, Drzezga A, von Reutern B, Schwaiger M, Wester HJ, Henriksen G.
J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm101129a[(11)C]Dimebon, radiosynthesis and lipophilicity of a new potential PET agent for imaging of Alzheimer's disease and Huntington's disease.
Gao M, Wang M, Hutchins GD, Zheng QH.
Bioorg Med Chem Lett · research support, non-u.s. gov't; research support, u.s. gov't, non-p.h.s.; journal article · DOI 10.1016/j.bmcl.2010.02.09418F stilbenes and styrylpyridines for PET imaging of A beta plaques in Alzheimer's disease: a miniperspective.
Kung HF, Choi SR, Qu W, Zhang W, Skovronsky D.
J Med Chem · research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/jm901039zNovel anilinophthalimide derivatives as potential probes for beta-amyloid plaque in the brain.
Duan XH, Qiao JP, Yang Y, Cui MC, Zhou JN, Liu BL.
Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2009.12.023Synthesis and evaluation of three 18F-labeled aminophenylbenzothiazoles as amyloid imaging agents.
Serdons K, Van Laere K, Janssen P, Kung HF, Bormans G, Verbruggen A.
J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm900871vPush-pull benzothiazole derivatives as probes for detecting beta-amyloid plaques in Alzheimer's brains.
Ono M, Hayashi S, Kimura H, Kawashima H, Nakayama M, Saji H.
Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2009.08.032Synthesis and evaluation of 18F-labeled 2-phenylbenzothiazoles as positron emission tomography imaging agents for amyloid plaques in Alzheimer's disease.
Serdons K, Terwinghe C, Vermaelen P, Van Laere K, Kung H, Mortelmans L, Bormans G, Verbruggen A.
J Med Chem · journal article · DOI 10.1021/jm8013376Synthesis of 18F-labelled 2-(4'-fluorophenyl)-1,3-benzothiazole and evaluation as amyloid imaging agent in comparison with [11C]PIB.
Serdons K, Verduyckt T, Vanderghinste D, Cleynhens J, Borghgraef P, Vermaelen P, Terwinghe C, Van Leuven F, Van Laere K, Kung H, Bormans G, Verbruggen A.
Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2008.12.069[(18)F]-labeled isoindol-1-one and isoindol-1,3-dione derivatives as potential PET imaging agents for detection of beta-amyloid fibrils.
Lee JH, Byeon SR, Kim Y, Lim SJ, Oh SJ, Moon DH, Yoo KH, Chung BY, Kim DJ.
Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2008.05.019Synthesis and evaluation of stilbenylbenzoxazole and stilbenylbenzothiazole derivatives for detecting beta-amyloid fibrils.
Lee JH, Byeon SR, Lim SJ, Oh SJ, Moon DH, Yoo KH, Chung BY, Kim DJ.
Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2007.10.004Ferulic acid and benzothiazole dimer derivatives with high binding affinity to beta-amyloid fibrils.
Byeon SR, Jin YJ, Lim SJ, Lee JH, Yoo KH, Shin KJ, Oh SJ, Kim DJ.
Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2007.04.079Dibenzothiazoles as novel amyloid-imaging agents.
Wu C, Wei J, Gao K, Wang Y.
Bioorg Med Chem · research support, non-u.s. gov't; journal article; research support, n.i.h., extramural · DOI 10.1016/j.bmc.2006.11.022Novel benzofuran derivatives for PET imaging of beta-amyloid plaques in Alzheimer's disease brains.
Ono M, Kawashima H, Nonaka A, Kawai T, Haratake M, Mori H, Kung MP, Kung HF, Saji H, Nakayama M.
J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm051176kSynthesis and evaluation of two 18F-labeled imidazo[1,2-a]pyridine analogues as potential agents for imaging beta-amyloid in Alzheimer's disease.
Zeng F, Southerland JA, Voll RJ, Votaw JR, Williams L, Ciliax BJ, Levey AI, Goodman MM.
Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2006.02.055