Fluorine in anti-HIV drugs approved by FDA from 1981 to 2023.
Han S, Lu Y.
Eur J Med Chem · review; journal article · DOI 10.1016/j.ejmech.2023.115586 PUBLIKATIONSREGISTRET
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Publikationer i urvalet
10 träffarSynthesis, docking, and biological studies of phenanthrene β-diketo acids as novel HIV-1 integrase inhibitors.
Sharma H, Sanchez TW, Neamati N, Detorio M, Schinazi RF, Cheng X, Buolamwini JK.
Bioorg Med Chem Lett · research support, non-u.s. gov't; research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1016/j.bmcl.2013.09.009Tetrazole and triazole as bioisosteres of carboxylic acid: discovery of diketo tetrazoles and diketo triazoles as anti-HCV agents.
Song WH, Liu MM, Zhong DW, Zhu YL, Bosscher M, Zhou L, Ye DY, Yuan ZH.
Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2013.06.045Discovery of a Potent HIV Integrase Inhibitor that Leads to a Prodrug with Significant anti-HIV Activity.
Seo BI, Uchil VR, Okello M, Mishra S, Ma XH, Nishonov M, Shu Q, Chi G, Nair V.
ACS Med Chem Lett · rapid-communication; journal article · DOI 10.1021/ml2001246Synthesis, biological evaluation and 3D-QSAR studies of 3-keto salicylic acid chalcones and related amides as novel HIV-1 integrase inhibitors.
Sharma H, Patil S, Sanchez TW, Neamati N, Schinazi RF, Buolamwini JK.
Bioorg Med Chem · research support, non-u.s. gov't; research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1016/j.bmc.2011.01.047Discovery of raltegravir, a potent, selective orally bioavailable HIV-integrase inhibitor for the treatment of HIV-AIDS infection.
Summa V, Petrocchi A, Bonelli F, Crescenzi B, Donghi M, Ferrara M, Fiore F, Gardelli C, Gonzalez Paz O, Hazuda DJ, Jones P, Kinzel O, Laufer R, Monteagudo E, Muraglia E, Nizi E, Orvieto F, Pace P, Pescatore G, Scarpelli R, Stillmock K, Witmer MV, Rowley M.
J Med Chem · journal article · DOI 10.1021/jm800245z3-Hydroxy-1,5-dihydro-pyrrol-2-one derivatives as advanced inhibitors of HIV integrase.
Kawasuji T, Fuji M, Yoshinaga T, Sato A, Fujiwara T, Kiyama R.
Bioorg Med Chem · journal article · DOI 10.1016/j.bmc.2007.05.052Calculation of binding energy using BLYP/MM for the HIV-1 integrase complexed with the S-1360 and two analogues.
Alves CN, Martí S, Castillo R, Andrés J, Moliner V, Tuñón I, Silla E.
Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2007.03.027Synthesis and biological evaluation of novel 5(H)-phenanthridin-6-ones, 5(H)-phenanthridin-6-one diketo acid, and polycyclic aromatic diketo acid analogs as new HIV-1 integrase inhibitors.
Patil S, Kamath S, Sanchez T, Neamati N, Schinazi RF, Buolamwini JK.
Bioorg Med Chem · research support, non-u.s. gov't; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1016/j.bmc.2006.11.026Synthesis and HIV-integrase strand transfer inhibition activity of 7-hydroxy[1,3]thiazolo[5,4-b]pyridin-5(4H)-ones.
Boros EE, Johns BA, Garvey EP, Koble CS, Miller WH.
Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2006.08.007