Physicochemical determinants of human renal clearance.
Varma MV, Feng B, Obach RS, Troutman MD, Chupka J, Miller HR, El-Kattan A.
J Med Chem · journal article · DOI 10.1021/jm900403j PUBLIKATIONSREGISTRET
Gå till forskningen.
Publikationsdata från Europe PMC och PubMed. Följ källhänvisningar från ämnesregistret till originalpublikationerna.
Publikationer som ChEBI hänvisar till för tomopenem. Visa hela publikationsregistret
En publikationsträff är inte en slutsats. Publikationslistan visar bibliografiska uppgifter. Eventuella forskningsutdrag visas separat med originalunderlag. En källhänvisning visar inte i sig effekt, dosering eller säkerhet.
Publikationer i urvalet
8 träffarAffinity of Tomopenem (CS-023) for penicillin-binding proteins in Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa.
Koga T, Sugihara C, Kakuta M, Masuda N, Namba E, Fukuoka T.
Antimicrob Agents Chemother · research-article; journal article · DOI 10.1128/aac.01433-08In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria.
Tanaka K, Mikamo H, Nakao K, Ichiishi T, Goto T, Yamagishi Y, Watanabe K.
Antimicrob Agents Chemother · research-article; journal article · DOI 10.1128/aac.00595-08Potent in vitro activity of tomopenem (CS-023) against methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa.
Koga T, Masuda N, Kakuta M, Namba E, Sugihara C, Fukuoka T.
Antimicrob Agents Chemother · research-article; journal article · DOI 10.1128/aac.00413-08Effect of impaired renal function on the pharmacokinetics of tomopenem (RO4908463/CS-023), a novel carbapenem.
Mallalieu NL, Lennon S, Liu M, Kirkpatrick C, Robson R, Luedin E, Davies BE.
Antimicrob Agents Chemother · clinical trial; research support, non-u.s. gov't; research-article; multicenter study; journal article · DOI 10.1128/aac.01249-07Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Obach RS, Lombardo F, Waters NJ.
Drug Metab Dispos · journal article · DOI 10.1124/dmd.108.020479Pharmacodynamics of the antibacterial effect and emergence of resistance to tomopenem, formerly RO4908463/CS-023, in an in vitro pharmacokinetic model of Staphylococcus aureus infection.
MacGowan AP, Bowker KE, Noel AR.
Antimicrob Agents Chemother · research-article; journal article · DOI 10.1128/aac.01153-07Pharmacokinetics and disposition of CS-023 (RO4908463), a novel parenteral carbapenem, in animals.
Shibayama T, Matsushita Y, Kawai K, Hirota T, Ikeda T, Kuwahara S.
Antimicrob Agents Chemother · research-article; journal article · DOI 10.1128/aac.00459-06