ActiQs / Forskning

PUBLIKATIONSREGISTRET

Gå till forskningen.

Publikationsdata från Europe PMC och PubMed. Följ källhänvisningar från ämnesregistret till originalpublikationerna.

Publikationer som ChEBI hänvisar till för fendiline. Visa hela publikationsregistret

En publikationsträff är inte en slutsats. Publikationslistan visar bibliografiska uppgifter. Eventuella forskningsutdrag visas separat med originalunderlag. En källhänvisning visar inte i sig effekt, dosering eller säkerhet.

Publikationer i urvalet

15 träffar

Bibliografisk träff 2024-01-13

Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnel.

Zhang SM, Paulin CBJ, Shu H, Yagüe-Capilla M, Michel M, Marttila P, Ortis F, Bwanika HC, Dirks C, Venkatram RP, Wiita E, Jemth AS, Almlöf I, Loseva O, Hormann FM, Koolmeister T, Linde E, Lee S, Llona-Minguez S, Haraldsson M, Axelsson H, Strömberg K, Homan EJ, Scobie M, Lundbäck T, Helleday T, Rudd SG.

iScience · research-article; journal article · DOI 10.1016/j.isci.2024.108907

Bibliografisk träff 2023-12-02

M335, a novel small-molecule STING agonist activates the immune response and exerts antitumor effects.

Zhao M, Fan W, Wang Y, Qiang P, Zheng Z, Shan H, Zhang M, Liu P, Wang Y, Li G, Li M, Hong L.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2023.116018

Bibliografisk träff 2023-07-19

A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.

Sutherland JJ, Yonchev D, Fekete A, Urban L.

Nat Commun · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/s41467-023-40064-9

Bibliografisk träff 2021-03-15

Scaffold repurposing of fendiline: Identification of potent KRAS plasma membrane localization inhibitors.

Wang P, van der Hoeven D, Ye N, Chen H, Liu Z, Ma X, Montufar-Solis D, Rehl KM, Cho KJ, Thapa S, Chen W, van der Hoeven R, Frost JA, Hancock JF, Zhou J.

Eur J Med Chem · research-article; journal article · DOI 10.1016/j.ejmech.2021.113381

Bibliografisk träff 2016-03-19

The chemosensitizing agent lubeluzole binds calmodulin and inhibits Ca(2+)/calmodulin-dependent kinase II.

Bruno C, Cavalluzzi MM, Rusciano MR, Lovece A, Carrieri A, Pracella R, Giannuzzi G, Polimeno L, Viale M, Illario M, Franchini C, Lentini G.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2016.03.045

Bibliografisk träff 2013-11-19

Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.

Settimo L, Bellman K, Knegtel RM.

Pharm Res · comparative study; journal article · DOI 10.1007/s11095-013-1232-z

Bibliografisk träff 2013-09-18

Antiprion compounds that reduce PrP(Sc) levels in dividing and stationary-phase cells.

Silber BM, Gever JR, Li Z, Gallardo-Godoy A, Renslo AR, Widjaja K, Irwin JJ, Rao S, Jacobson MP, Ghaemmaghami S, Prusiner SB.

Bioorg Med Chem · research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.bmc.2013.09.022

Bibliografisk träff 2013-01-29

New potent calcimimetics: I. Discovery of a series of novel trisubstituted ureas.

Temal T, Jary H, Auberval M, Lively S, Guédin D, Vevert JP, Deprez P.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2013.01.078

Bibliografisk träff 2012-07-03

Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.

Wiśniowska B, Mendyk A, Fijorek K, Glinka A, Polak S.

J Appl Toxicol · comparative study; research support, non-u.s. gov't; validation study; journal article · DOI 10.1002/jat.2784

Bibliografisk träff 2012-06-11

Chemocentric informatics approach to drug discovery: identification and experimental validation of selective estrogen receptor modulators as ligands of 5-hydroxytryptamine-6 receptors and as potential cognition enhancers.

Hajjo R, Setola V, Roth BL, Tropsha A.

J Med Chem · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/jm2011657

Bibliografisk träff 2012-05-15

Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.

Karlgren M, Vildhede A, Norinder U, Wisniewski JR, Kimoto E, Lai Y, Haglund U, Artursson P.

J Med Chem · research support, non-u.s. gov't; research-article; journal article · DOI 10.1021/jm300212s

Bibliografisk träff 2010-11-01

Development, validation, and use of quantitative structure-activity relationship models of 5-hydroxytryptamine (2B) receptor ligands to identify novel receptor binders and putative valvulopathic compounds among common drugs.

Hajjo R, Grulke CM, Golbraikh A, Setola V, Huang XP, Roth BL, Tropsha A.

J Med Chem · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/jm100600y

Bibliografisk träff 2010-06-17

LuxR-dependent quorum sensing: computer aided discovery of new inhibitors structurally unrelated to N-acylhomoserine lactones.

Soulère L, Sabbah M, Fontaine F, Queneau Y, Doutheau A.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2010.06.081

Bibliografisk träff 2008-05-06

Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).

Pedersen JM, Matsson P, Bergström CA, Norinder U, Hoogstraate J, Artursson P.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm7015683

Bibliografisk träff 2007-11-21

Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.

Kornhuber J, Tripal P, Reichel M, Terfloth L, Bleich S, Wiltfang J, Gulbins E.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm070524a