Acridine-O<sup>6</sup>-benzylguanine hybrids: Synthesis, DNA binding, MGMT inhibition and antiproliferative activity.
Franco Pinto J, Fillion A, Duchambon P, Bombard S, Granzhan A.
Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2021.113909 PUBLIKATIONSREGISTRET
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Zhu R, Liu MC, Luo MZ, Penketh PG, Baumann RP, Shyam K, Sartorelli AC.
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Okamoto M, Saito N, Kojima H, Okabe T, Takeda K, Ichijo H, Furuya T, Nagano T.
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Nelson ME, Loktionova NA, Pegg AE, Moschel RC.
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Gibson AE, Arris CE, Bentley J, Boyle FT, Curtin NJ, Davies TG, Endicott JA, Golding BT, Grant S, Griffin RJ, Jewsbury P, Johnson LN, Mesguiche V, Newell DR, Noble ME, Tucker JA, Whitfield HJ.
J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm020056zMonosaccharide-linked inhibitors of O(6)-methylguanine-DNA methyltransferase (MGMT): synthesis, molecular modeling, and structure-activity relationships.
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