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Publikationer i urvalet

40 träffar

Bibliografisk träff 2023-07-19

A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.

Sutherland JJ, Yonchev D, Fekete A, Urban L.

Nat Commun · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/s41467-023-40064-9

Bibliografisk träff 2019-04-30

Synthetic small-molecule RNA ligands: future prospects as therapeutic agents.

Di Giorgio A, Duca M.

Medchemcomm · review-article; review; journal article · DOI 10.1039/c9md00195f

Bibliografisk träff 2019-04-25

Synthesis, ribosomal selectivity, and antibacterial activity of netilmicin 4'-derivatives.

Sonousi A, Shcherbakov D, Vasella A, Böttger EC, Crich D.

Medchemcomm · research-article; journal article · DOI 10.1039/c9md00153k

Bibliografisk träff 2016-09-20

Tyrosyl-DNA phosphodiesterase inhibitors: Progress and potential.

Laev SS, Salakhutdinov NF, Lavrik OI.

Bioorg Med Chem · research support, non-u.s. gov't; review; journal article · DOI 10.1016/j.bmc.2016.09.045

Bibliografisk träff 2015-09-30

Synthesis and Biological Activity of Mono- and Di-N-acylated Aminoglycosides.

Thamban Chandrika N, Green KD, Houghton JL, Garneau-Tsodikova S.

ACS Med Chem Lett · rapid-communication; journal article · DOI 10.1021/acsmedchemlett.5b00255

Bibliografisk träff 2011-12-30

Pre-microRNA binding aminoglycosides and antitumor drugs as inhibitors of Dicer catalyzed microRNA processing.

Maiti M, Nauwelaerts K, Herdewijn P.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2011.12.103

Bibliografisk träff 2010-11-09

Prediction of drug intestinal absorption by new linear and non-linear QSPR.

Talevi A, Goodarzi M, Ortiz EV, Duchowicz PR, Bellera CL, Pesce G, Castro EA, Bruno-Blanch LE.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2010.11.005

Bibliografisk träff 2010-09-10

Predicting phospholipidosis using machine learning.

Lowe R, Glen RC, Mitchell JB.

Mol Pharm · research support, non-u.s. gov't; research-article; journal article · DOI 10.1021/mp100103e

Bibliografisk träff 2010-06-28

In vitro antimicrobial activity and mutant prevention concentration of colistin against Acinetobacter baumannii.

Cai Y, Li R, Liang B, Bai N, Liu Y, Wang R.

Antimicrob Agents Chemother · research support, non-u.s. gov't; research-article; journal article · DOI 10.1128/aac.00264-10

Bibliografisk träff 2010-03-22

Homozygous triplicate mutations in three 16S rRNA genes responsible for high-level aminoglycoside resistance in Nocardia farcinica clinical isolates from a Canada-wide bovine mastitis epizootic.

Kogure T, Shimada R, Ishikawa J, Yazawa K, Brown JM, Mikami Y, Gonoi T.

Antimicrob Agents Chemother · research support, non-u.s. gov't; research-article; journal article · DOI 10.1128/aac.00021-10

Bibliografisk träff 2010-02-09

Mutant APH(2'')-IIa enzymes with increased activity against amikacin and isepamicin.

Toth M, Frase H, Chow JW, Smith C, Vakulenko SB.

Antimicrob Agents Chemother · research-article; journal article; research support, n.i.h., extramural · DOI 10.1128/aac.01444-09

Bibliografisk träff 2010-01-01

Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.

Fourches D, Barnes JC, Day NC, Bradley P, Reed JZ, Tropsha A.

Chem Res Toxicol · research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1021/tx900326k

Bibliografisk träff 2009-11-02

First isolation of the blaOXA-23 carbapenemase gene from an environmental Acinetobacter baumannii isolate.

Girlich D, Poirel L, Nordmann P.

Antimicrob Agents Chemother · letter; research support, non-u.s. gov't · DOI 10.1128/aac.00861-09

Bibliografisk träff 2009-11-02

Screening and quantification of the expression of antibiotic resistance genes in Acinetobacter baumannii with a microarray.

Coyne S, Guigon G, Courvalin P, Périchon B.

Antimicrob Agents Chemother · research support, non-u.s. gov't; research-article; journal article · DOI 10.1128/aac.01037-09

Bibliografisk träff 2009-08-01

Physicochemical determinants of human renal clearance.

Varma MV, Feng B, Obach RS, Troutman MD, Chupka J, Miller HR, El-Kattan A.

J Med Chem · journal article · DOI 10.1021/jm900403j

Bibliografisk träff 2009-07-27

In vivo antibacterial activity of vertilmicin, a new aminoglycoside antibiotic.

You XF, Li CR, Yang XY, Yuan M, Zhang WX, Lou RH, Wang YM, Li GQ, Chen HZ, Song DQ, Sun CH, Cen S, Yu LY, Zhao LX, Jiang JD.

Antimicrob Agents Chemother · research support, non-u.s. gov't; research-article; journal article · DOI 10.1128/aac.00223-09

Bibliografisk träff 2009-04-06

AAC(6')-Iaf, a novel aminoglycoside 6'-N-acetyltransferase from multidrug-resistant Pseudomonas aeruginosa clinical isolates.

Kitao T, Miyoshi-Akiyama T, Kirikae T.

Antimicrob Agents Chemother · research support, non-u.s. gov't; research-article; journal article · DOI 10.1128/aac.01360-08

Bibliografisk träff 2008-10-06

Plasmid-mediated 16S rRNA methylases among extended-spectrum beta-lactamase-producing Enterobacteriaceae isolates.

Berçot B, Poirel L, Nordmann P.

Antimicrob Agents Chemother · letter; research support, non-u.s. gov't · DOI 10.1128/aac.00882-08

Bibliografisk träff 2008-10-04

Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.

Santana L, González-Díaz H, Quezada E, Uriarte E, Yáñez M, Viña D, Orallo F.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm800656v

Bibliografisk träff 2008-08-18

In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme.

Li CR, Yang XY, Lou RH, Zhang WX, Wang YM, Yuan M, Li Y, Chen HZ, Hong B, Sun CH, Zhao LX, Li ZR, Jiang JD, You XF.

Antimicrob Agents Chemother · research support, non-u.s. gov't; research-article; journal article · DOI 10.1128/aac.01400-07

Bibliografisk träff 2008-07-21

Plasmid-mediated quinolone resistance pump QepA2 in an Escherichia coli isolate from France.

Cattoir V, Poirel L, Nordmann P.

Antimicrob Agents Chemother · research support, non-u.s. gov't; research-article; journal article · DOI 10.1128/aac.00638-08

Bibliografisk träff 2008-06-02

Spread of OXA-48-positive carbapenem-resistant Klebsiella pneumoniae isolates in Istanbul, Turkey.

Carrër A, Poirel L, Eraksoy H, Cagatay AA, Badur S, Nordmann P.

Antimicrob Agents Chemother · research support, non-u.s. gov't; research-article; journal article · DOI 10.1128/aac.01672-07

Bibliografisk träff 2008-04-21

Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.

Obach RS, Lombardo F, Waters NJ.

Drug Metab Dispos · journal article · DOI 10.1124/dmd.108.020479

Bibliografisk träff 2008-01-01

Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.

Kruhlak NL, Choi SS, Contrera JF, Weaver JL, Willard JM, Hastings KL, Sancilio LF.

Toxicol Mech Methods · journal article · DOI 10.1080/15376510701857262

Bibliografisk träff 2007-09-17

Novel plasmid-mediated 16S rRNA m1A1408 methyltransferase, NpmA, found in a clinically isolated Escherichia coli strain resistant to structurally diverse aminoglycosides.

Wachino J, Shibayama K, Kurokawa H, Kimura K, Yamane K, Suzuki S, Shibata N, Ike Y, Arakawa Y.

Antimicrob Agents Chemother · research support, non-u.s. gov't; research-article; journal article · DOI 10.1128/aac.00926-07

Bibliografisk träff 2007-08-06

Pseudomonas aeruginosa may accumulate drug resistance mechanisms without losing its ability to cause bloodstream infections.

Hocquet D, Berthelot P, Roussel-Delvallez M, Favre R, Jeannot K, Bajolet O, Marty N, Grattard F, Mariani-Kurkdjian P, Bingen E, Husson MO, Couetdic G, Plésiat P.

Antimicrob Agents Chemother · research support, non-u.s. gov't; research-article; journal article · DOI 10.1128/aac.00503-07

Bibliografisk träff 2007-04-30

Transferable resistance to aminoglycosides by methylation of G1405 in 16S rRNA and to hydrophilic fluoroquinolones by QepA-mediated efflux in Escherichia coli.

Périchon B, Courvalin P, Galimand M.

Antimicrob Agents Chemother · research-article; journal article · DOI 10.1128/aac.00143-07

Bibliografisk träff 2007-04-30

Characterization of an integron carrying blaIMP-1 and a new aminoglycoside resistance gene, aac(6')-31, and its dissemination among genetically unrelated clinical isolates in a Brazilian hospital.

Mendes RE, Castanheira M, Toleman MA, Sader HS, Jones RN, Walsh TR.

Antimicrob Agents Chemother · research-article; journal article · DOI 10.1128/aac.00838-06

Bibliografisk träff 2007-04-12

Evaluation of a published in silico model and construction of a novel Bayesian model for predicting phospholipidosis inducing potential.

Pelletier DJ, Gehlhaar D, Tilloy-Ellul A, Johnson TO, Greene N.

J Chem Inf Model · journal article · DOI 10.1021/ci6004542

Bibliografisk träff 2007-03-19

High-level gentamicin resistance mediated by a Tn4001-like transposon in seven nonclonal hospital isolates of Streptococcus pasteurianus.

Chow VC, Hawkey PM, Chan EW, Chin ML, Au TK, Fung DK, Chan RC.

Antimicrob Agents Chemother · research-article; journal article · DOI 10.1128/aac.00603-06