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Publikationer i urvalet

12 träffar

Bibliografisk träff 2022-01-19

In Vitro and In Vivo Inhibition of the <i>Mycobacterium tuberculosis</i> Phosphopantetheinyl Transferase PptT by Amidinoureas.

Ottavi S, Scarry SM, Mosior J, Ling Y, Roberts J, Singh A, Zhang D, Goullieux L, Roubert C, Bacqué E, Lagiakos HR, Vendome J, Moraca F, Li K, Perkowski AJ, Ramesh R, Bowler MM, Tracy W, Feher VA, Sacchettini JC, Gold BS, Nathan CF, Aubé J.

J Med Chem · research support, non-u.s. gov't; research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1021/acs.jmedchem.1c01565

Bibliografisk träff 2021-04-28

Design, synthesis and evaluation of novel 9-arylalkyl-10-methylacridinium derivatives as highly potent FtsZ-targeting antibacterial agents.

Song D, Zhang N, Zhang P, Zhang N, Chen W, Zhang L, Guo T, Gu X, Ma S.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2021.113480

Bibliografisk träff 2020-02-12

The synthesis and biological evaluation of sanguinarine derivatives as anti-non-small cell lung cancer agents.

Jiang L, Wang X, Wang Y, Xu F, Zhang Z, Ding K, Lu X.

RSC Med Chem · research-article; journal article · DOI 10.1039/c9md00494g

Bibliografisk träff 2018-04-07

Novel 5-methyl-2-phenylphenanthridium derivatives as FtsZ-targeting antibacterial agents from structural simplification of natural product sanguinarine.

Liu J, Ma R, Bi F, Zhang F, Hu C, Venter H, Semple SJ, Ma S.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2018.04.015

Bibliografisk träff 2017-06-03

Drug development against tuberculosis: Impact of alkaloids.

Mishra SK, Tripathi G, Kishore N, Singh RK, Singh A, Tiwari VK.

Eur J Med Chem · review; journal article · DOI 10.1016/j.ejmech.2017.06.005

Bibliografisk träff 2014-04-19

Synthesis of 5-methyl phenanthridium derivatives: a new class of human DOPA decarboxylase inhibitors.

Cheng P, Zhou J, Qing Z, Kang W, Liu S, Liu W, Xie H, Zeng J.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2014.04.047

Bibliografisk träff 2012-10-02

Antibacterial activity of substituted 5-methylbenzo[c]phenanthridinium derivatives.

Parhi A, Kelley C, Kaul M, Pilch DS, LaVoie EJ.

Bioorg Med Chem Lett · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.bmcl.2012.09.097

Bibliografisk träff 2009-09-06

Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Yuan J, Johnson RL, Huang R, Wichterman J, Jiang H, Hayton K, Fidock DA, Wellems TE, Inglese J, Austin CP, Su XZ.

Nat Chem Biol · research support, n.i.h., intramural; research-article; journal article; research support, n.i.h., extramural · DOI 10.1038/nchembio.215

Bibliografisk träff 2009-08-13

Structure-activity relationship of isoform selective inhibitors of Rac1/1b GTPase nucleotide binding.

Beausoleil E, Chauvignac C, Taverne T, Lacombe S, Pognante L, Leblond B, Pallares D, Oliveira CD, Bachelot F, Carton R, Peillon H, Coutadeur S, Picard V, Lambeng N, Désiré L, Schweighoffer F.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2009.08.037

Bibliografisk träff 2008-05-06

Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).

Pedersen JM, Matsson P, Bergström CA, Norinder U, Hoogstraate J, Artursson P.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm7015683

Bibliografisk träff 2007-04-08

Chemical genetics reveals a complex functional ground state of neural stem cells.

Diamandis P, Wildenhain J, Clarke ID, Sacher AG, Graham J, Bellows DS, Ling EK, Ward RJ, Jamieson LG, Tyers M, Dirks PB.

Nat Chem Biol · research support, non-u.s. gov't; journal article · DOI 10.1038/nchembio873

Bibliografisk träff 1999-06-01

Structural considerations of NK109, an antitumor benzo[c]phenanthridine alkaloid.

Nakanishi T, Suzuki M, Saimoto A, Kabasawa T.

J Nat Prod · journal article · DOI 10.1021/np990005d