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Publikationer i urvalet

9 träffar

Bibliografisk träff 2021-08-18

X-ray Crystallography-Guided Design, Antitumor Efficacy, and QSAR Analysis of Metabolically Stable Cyclopenta-Pyrimidinyl Dihydroquinoxalinone as a Potent Tubulin Polymerization Inhibitor.

Banerjee S, Mahmud F, Deng S, Ma L, Yun MK, Fakayode SO, Arnst KE, Yang L, Chen H, Wu Z, Lukka PB, Parmar K, Meibohm B, White SW, Wang Y, Li W, Miller DD.

J Med Chem · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/acs.jmedchem.1c01202

Bibliografisk träff 2021-02-12

Potential of substituted quinazolines to interact with multiple targets in the treatment of cancer.

Choudhary S, Doshi A, Luckett-Chastain L, Ihnat M, Hamel E, Mooberry SL, Gangjee A.

Bioorg Med Chem · research support, non-u.s. gov't; research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1016/j.bmc.2021.116061

Bibliografisk träff 2018-08-01

Evaluation of 4-phenylamino-substituted naphthalene-1,2-diones as tubulin polymerization inhibitors.

Yang H, An B, Li X, Zeng W.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2018.07.047

Bibliografisk träff 2018-04-12

Synthesis and evaluation of new 2-chloro-4-aminopyrimidine and 2,6-dimethyl-4-aminopyrimidine derivatives as tubulin polymerization inhibitors.

Xu S, An B, Li Y, Luo X, Li X, Jia X.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2018.04.026

Bibliografisk träff 2018-03-06

Synthesis and Biological Evaluation of Selenium-Containing 4-Anilinoquinazoline Derivatives as Novel Antimitotic Agents.

An B, Wang B, Hu J, Xu S, Huang L, Li X, Chan ASC.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jmedchem.8b00128

Bibliografisk träff 2016-06-02

Design, Synthesis, and Evaluation of in Vitro and in Vivo Anticancer Activity of 4-Substituted Coumarins: A Novel Class of Potent Tubulin Polymerization Inhibitors.

Cao D, Liu Y, Yan W, Wang C, Bai P, Wang T, Tang M, Wang X, Yang Z, Ma B, Ma L, Lei L, Wang F, Xu B, Zhou Y, Yang T, Chen L.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jmedchem.6b00158

Bibliografisk träff 2010-02-04

Discovery of N-methyl-4-(4-methoxyanilino)quinazolines as potent apoptosis inducers. Structure-activity relationship of the quinazoline ring.

Sirisoma N, Pervin A, Zhang H, Jiang S, Adam Willardsen J, Anderson MB, Mather G, Pleiman CM, Kasibhatla S, Tseng B, Drewe J, Cai SX.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2010.01.155

Bibliografisk träff 2009-05-05

Discovery of 4-anilino-N-methylthieno[3,2-d]pyrimidines and 4-anilino-N-methylthieno[2,3-d]pyrimidines as potent apoptosis inducers.

Kemnitzer W, Sirisoma N, May C, Tseng B, Drewe J, Cai SX.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2009.04.145

Bibliografisk träff 2009-04-01

Discovery of N-(4-methoxyphenyl)-N,2-dimethylquinazolin-4-amine, a potent apoptosis inducer and efficacious anticancer agent with high blood brain barrier penetration.

Sirisoma N, Pervin A, Zhang H, Jiang S, Willardsen JA, Anderson MB, Mather G, Pleiman CM, Kasibhatla S, Tseng B, Drewe J, Cai SX.

J Med Chem · journal article · DOI 10.1021/jm801315b