Selective acetylcholinesterase inhibitors derived from muscle relaxant dantrolene.
Aoyama H, Doura T.
Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2019.126888 PUBLIKATIONSREGISTRET
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Eur J Med Chem · research support, non-u.s. gov't; journal article; research support, n.i.h., extramural · DOI 10.1016/j.ejmech.2012.06.051Tacrine-ferulic acid-nitric oxide (NO) donor trihybrids as potent, multifunctional acetyl- and butyrylcholinesterase inhibitors.
Chen Y, Sun J, Fang L, Liu M, Peng S, Liao H, Lehmann J, Zhang Y.
J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm300106zBenzofurans from Styrax agrestis as acetylcholinesterase inhibitors: structure-activity relationships and molecular modeling studies.
Liu J, Dumontet V, Simonin AL, Iorga BI, Guerineau V, Litaudon M, Nguyen VH, Gueritte F.
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Luo W, Li YP, He Y, Huang SL, Li D, Gu LQ, Huang ZS.
Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2011.03.058Design, synthesis and structure-activity relationship (SAR) studies of 2,4-disubstituted pyrimidine derivatives: dual activity as cholinesterase and Aβ-aggregation inhibitors.
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Goh CW, Aw CC, Lee JH, Chen CP, Browne ER.
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Nat Chem Biol · research support, n.i.h., intramural; research-article; journal article; research support, n.i.h., extramural · DOI 10.1038/nchembio.215Novel donepezil-based inhibitors of acetyl- and butyrylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation.
Camps P, Formosa X, Galdeano C, Gómez T, Muñoz-Torrero D, Scarpellini M, Viayna E, Badia A, Clos MV, Camins A, Pallàs M, Bartolini M, Mancini F, Andrisano V, Estelrich J, Lizondo M, Bidon-Chanal A, Luque FJ.
J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm8001313First gallamine-tacrine hybrid: design and characterization at cholinesterases and the M2 muscarinic receptor.
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J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm0496741Synthesis, in vitro pharmacology, and molecular modeling of syn-huprines as acetylcholinesterase inhibitors.
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J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm010949bHeterodimeric tacrine-based acetylcholinesterase inhibitors: investigating ligand-peripheral site interactions.
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J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm990224w