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Publikationer i urvalet

8 träffar

Bibliografisk träff 2021-11-01

Discovery of the Triazolo[1,5-<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance.

Wang S, Wang SQ, Teng QX, Lei ZN, Chen ZS, Chen XB, Liu HM, Yu B.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jmedchem.1c01498

Bibliografisk träff 2021-03-17

Discovery of Encequidar, First-in-Class Intestine Specific P-glycoprotein Inhibitor.

Smolinski MP, Urgaonkar S, Pitzonka L, Cutler M, Lee G, Suh KH, Lau JYN.

J Med Chem · journal article · DOI 10.1021/acs.jmedchem.0c01826

Bibliografisk träff 2019-10-19

Green chemistry appended synthesis, metabolic stability and pharmacokinetic assessment of medicinally important chromene dihydropyrimidinones.

Dash AK, Mukherjee D, Dhulap A, Haider S, Kumar D.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2019.126750

Bibliografisk träff 2019-02-11

Pharmacokinetic evaluation of medicinally important synthetic N,N' diindolylmethane glucoside: Improved synthesis and metabolic stability.

Magotra A, Gour A, Sharma DK, Dash AK, Singh G, Mukherjee D, Nandi U.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2019.02.010

Bibliografisk träff 2018-01-23

Comprehensive Synthesis of Amino Acid-Derived Thiazole Peptidomimetic Analogues to Understand the Enigmatic Drug/Substrate-Binding Site of P-Glycoprotein.

Patel BA, Abel B, Barbuti AM, Velagapudi UK, Chen ZS, Ambudkar SV, Talele TT.

J Med Chem · research support, non-u.s. gov't; research-article; journal article · DOI 10.1021/acs.jmedchem.7b01340

Bibliografisk träff 2017-12-28

Inhibit or Evade Multidrug Resistance P-Glycoprotein in Cancer Treatment.

Waghray D, Zhang Q.

J Med Chem · research-article; review; journal article; research support, n.i.h., extramural · DOI 10.1021/acs.jmedchem.7b01457

Bibliografisk träff 2012-03-27

Structure-activity relationships, ligand efficiency, and lipophilic efficiency profiles of benzophenone-type inhibitors of the multidrug transporter P-glycoprotein.

Jabeen I, Pleban K, Rinner U, Chiba P, Ecker GF.

J Med Chem · research support, non-u.s. gov't; research-article; journal article · DOI 10.1021/jm201705f

Bibliografisk träff 2008-11-01

Bis-pyranobenzoquinones as a new family of reversal agents of the multidrug resistance phenotype mediated by P-glycoprotein in mammalian cells and the protozoan parasite Leishmania.

Jiménez-Alonso S, Pérez-Lomas AL, Estévez-Braun A, Muñoz Martinez F, Chávez Orellana H, Ravelo AG, Gamarro F, Castanys S, López M.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm800403b